160 related articles for article (PubMed ID: 32252280)
1. Marine-Inspired Bis-indoles Possessing Antiproliferative Activity against Breast Cancer; Design, Synthesis, and Biological Evaluation.
Eldehna WM; Hassan GS; Al-Rashood ST; Alkahtani HM; A Almehizia A; Al-Ansary GH
Mar Drugs; 2020 Apr; 18(4):. PubMed ID: 32252280
[TBL] [Abstract][Full Text] [Related]
2. Synthesis, Biological Evaluation and In Silico Studies of Certain Oxindole-Indole Conjugates as Anticancer CDK Inhibitors.
Al-Warhi T; El Kerdawy AM; Aljaeed N; Ismael OE; Ayyad RR; Eldehna WM; Abdel-Aziz HA; Al-Ansary GH
Molecules; 2020 Apr; 25(9):. PubMed ID: 32349307
[TBL] [Abstract][Full Text] [Related]
3. New thieno[3,2-d]pyrimidine-based derivatives: Design, synthesis and biological evaluation as antiproliferative agents, EGFR and ARO inhibitors inducing apoptosis in breast cancer cells.
Farghaly AM; AboulWafa OM; Baghdadi HH; Abd El Razik HA; Sedra SMY; Shamaa MM
Bioorg Chem; 2021 Oct; 115():105208. PubMed ID: 34365057
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and Preclinical Evaluation of Indole Triazole Conjugates as Microtubule Targeting Agents that are Effective against MCF-7 Breast Cancer Cell Lines.
Yele V; Pindiprolu SKSS; Sana S; Ramamurty DSVNM; Madasi JRK; Vadlamani S
Anticancer Agents Med Chem; 2021; 21(8):1047-1055. PubMed ID: 32981511
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach.
Preti D; Romagnoli R; Rondanin R; Cacciari B; Hamel E; Balzarini J; Liekens S; Schols D; Estévez-Sarmiento F; Quintana J; Estévez F
J Enzyme Inhib Med Chem; 2018 Dec; 33(1):1225-1238. PubMed ID: 30141353
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis and molecular docking study of new pyrimidine-based hydrazones with selective anti-proliferative activity against MCF-7 and MDA-MB-231 human breast cancer cell lines.
Badawi WA; Samir M; Fathy HM; Okda TM; Noureldin MH; Atwa GMK; AboulWafa OM
Bioorg Chem; 2023 Sep; 138():106610. PubMed ID: 37210828
[TBL] [Abstract][Full Text] [Related]
7. Development of isatin-thiazolo[3,2-a]benzimidazole hybrids as novel CDK2 inhibitors with potent in vitro apoptotic anti-proliferative activity: Synthesis, biological and molecular dynamics investigations.
Eldehna WM; El Hassab MA; Abo-Ashour MF; Al-Warhi T; Elaasser MM; Safwat NA; Suliman H; Ahmed MF; Al-Rashood ST; Abdel-Aziz HA; El-Haggar R
Bioorg Chem; 2021 May; 110():104748. PubMed ID: 33684714
[TBL] [Abstract][Full Text] [Related]
8. Analogue-based design, synthesis and biological evaluation of 3-substituted-(methylenehydrazono)indolin-2-ones as anticancer agents.
Dweedar HE; Mahrous H; Ibrahim HS; Abdel-Aziz HA
Eur J Med Chem; 2014 May; 78():275-80. PubMed ID: 24686014
[TBL] [Abstract][Full Text] [Related]
9. New (E)-1-alkyl-1H-benzo[d]imidazol-2-yl)methylene)indolin-2-ones: Synthesis, in vitro cytotoxicity evaluation and apoptosis inducing studies.
Sharma P; Thummuri D; Reddy TS; Senwar KR; Naidu VGM; Srinivasulu G; Bharghava SK; Shankaraiah N
Eur J Med Chem; 2016 Oct; 122():584-600. PubMed ID: 27448916
[TBL] [Abstract][Full Text] [Related]
10. Design and synthesis of newer 1,3,4-oxadiazole and 1,2,4-triazole based Topsentin analogues as anti-proliferative agent targeting tubulin.
Naaz F; Ahmad F; Lone BA; Pokharel YR; Fuloria NK; Fuloria S; Ravichandran M; Pattabhiraman L; Shafi S; Shahar Yar M
Bioorg Chem; 2020 Jan; 95():103519. PubMed ID: 31884140
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and Cytotoxic Activity of Novel Mono- and Bis-Indole Derivatives: Analogues of Marine Alkaloid Nortopsentin.
Kamel MM; Abdel-Hameid MK; El-Nassan HB; El-Khouly EA
Med Chem; 2021; 17(7):779-789. PubMed ID: 32386499
[TBL] [Abstract][Full Text] [Related]
12. Discovery of 3,6-disubstituted pyridazines as a novel class of anticancer agents targeting cyclin-dependent kinase 2: synthesis, biological evaluation and in silico insights.
Sabt A; Eldehna WM; Al-Warhi T; Alotaibi OJ; Elaasser MM; Suliman H; Abdel-Aziz HA
J Enzyme Inhib Med Chem; 2020 Dec; 35(1):1616-1630. PubMed ID: 32781872
[TBL] [Abstract][Full Text] [Related]
13. New hydrazonoindolin-2-ones: Synthesis, exploration of the possible anti-proliferative mechanism of action and encapsulation into PLGA microspheres.
Attia MI; Eldehna WM; Afifi SA; Keeton AB; Piazza GA; Abdel-Aziz HA
PLoS One; 2017; 12(7):e0181241. PubMed ID: 28742842
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis and apoptosis inducing effect of novel (Z)-3-(3'-methoxy-4'-(2-amino-2-oxoethoxy)-benzylidene)indolin-2-ones as potential antitumour agents.
Senwar KR; Reddy TS; Thummuri D; Sharma P; Naidu VG; Srinivasulu G; Shankaraiah N
Eur J Med Chem; 2016 Aug; 118():34-46. PubMed ID: 27128173
[TBL] [Abstract][Full Text] [Related]
15. A New CDK2 Inhibitor with 3-Hydrazonoindolin-2-One Scaffold Endowed with Anti-Breast Cancer Activity: Design, Synthesis, Biological Evaluation, and In Silico Insights.
Al-Sanea MM; Obaidullah AJ; Shaker ME; Chilingaryan G; Alanazi MM; Alsaif NA; Alkahtani HM; Alsubaie SA; Abdelgawad MA
Molecules; 2021 Jan; 26(2):. PubMed ID: 33466812
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and Antitumor Activity of New Thiazole Nortopsentin Analogs.
Spanò V; Attanzio A; Cascioferro S; Carbone A; Montalbano A; Barraja P; Tesoriere L; Cirrincione G; Diana P; Parrino B
Mar Drugs; 2016 Dec; 14(12):. PubMed ID: 27983614
[TBL] [Abstract][Full Text] [Related]
17. 1,2,4-Oxadiazole Topsentin Analogs with Antiproliferative Activity against Pancreatic Cancer Cells, Targeting GSK3β Kinase.
Carbone D; Parrino B; Cascioferro S; Pecoraro C; Giovannetti E; Di Sarno V; Musella S; Auriemma G; Cirrincione G; Diana P
ChemMedChem; 2021 Feb; 16(3):537-554. PubMed ID: 33141472
[TBL] [Abstract][Full Text] [Related]
18. Novel [(3-indolylmethylene)hydrazono]indolin-2-ones as apoptotic anti-proliferative agents: design, synthesis and in vitro biological evaluation.
Eldehna WM; Abo-Ashour MF; Ibrahim HS; Al-Ansary GH; Ghabbour HA; Elaasser MM; Ahmed HYA; Safwat NA
J Enzyme Inhib Med Chem; 2018 Dec; 33(1):686-700. PubMed ID: 29560733
[TBL] [Abstract][Full Text] [Related]
19. Antiproliferative activity, enzymatic inhibition and apoptosis-promoting effects of benzoxazole-based hybrids on human breast cancer cells.
Omar AME; AboulWafa OM; Amr ME; El-Shoukrofy MS
Bioorg Chem; 2021 Apr; 109():104752. PubMed ID: 33657444
[TBL] [Abstract][Full Text] [Related]
20. Synthesis, antiproliferative and apoptosis induction potential activities of novel bis(indolyl)hydrazide-hydrazone derivatives.
Sreenivasulu R; Reddy KT; Sujitha P; Kumar CG; Raju RR
Bioorg Med Chem; 2019 Mar; 27(6):1043-1055. PubMed ID: 30773423
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]