These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

224 related articles for article (PubMed ID: 32255680)

  • 1. The inducible β5i proteasome subunit contributes to proinsulin degradation in GRP94-deficient β-cells and is overexpressed in type 2 diabetes pancreatic islets.
    Khilji MS; Bresson SE; Verstappen D; Pihl C; Andersen PAK; Agergaard JB; Dahlby T; Bryde TH; Klindt K; Nielsen CK; Walentinsson A; Zivkovic D; Bousquet MP; Tyrberg B; Richardson SJ; Morgan NG; Mandrup-Poulsen T; Marzec MT
    Am J Physiol Endocrinol Metab; 2020 Jun; 318(6):E892-E900. PubMed ID: 32255680
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 Is Essential for Proinsulin Handling.
    Ghiasi SM; Dahlby T; Hede Andersen C; Haataja L; Petersen S; Omar-Hmeadi M; Yang M; Pihl C; Bresson SE; Khilji MS; Klindt K; Cheta O; Perone MJ; Tyrberg B; Prats C; Barg S; Tengholm A; Arvan P; Mandrup-Poulsen T; Marzec MT
    Diabetes; 2019 Apr; 68(4):747-760. PubMed ID: 30670477
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Endoplasmic reticulum oxidoreductin-1α (Ero1α) improves folding and secretion of mutant proinsulin and limits mutant proinsulin-induced endoplasmic reticulum stress.
    Wright J; Birk J; Haataja L; Liu M; Ramming T; Weiss MA; Appenzeller-Herzog C; Arvan P
    J Biol Chem; 2013 Oct; 288(43):31010-8. PubMed ID: 24022479
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Endoplasmic reticulum stress response in an INS-1 pancreatic beta-cell line with inducible expression of a folding-deficient proinsulin.
    Hartley T; Siva M; Lai E; Teodoro T; Zhang L; Volchuk A
    BMC Cell Biol; 2010 Jul; 11():59. PubMed ID: 20659334
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The intermediate proteasome is constitutively expressed in pancreatic beta cells and upregulated by stimulatory, low concentrations of interleukin 1 β.
    Khilji MS; Verstappen D; Dahlby T; Burstein Prause MC; Pihl C; Bresson SE; Bryde TH; Keller Andersen PA; Klindt K; Zivkovic D; Bousquet-Dubouch MP; Tyrberg B; Mandrup-Poulsen T; Marzec MT
    PLoS One; 2020; 15(2):e0222432. PubMed ID: 32053590
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Proteasomal degradation of WT proinsulin in pancreatic beta cells.
    Xu X; Arunagiri A; Haataja L; Alam M; Ji S; Qi L; Tsai B; Liu M; Arvan P
    J Biol Chem; 2022 Oct; 298(10):102406. PubMed ID: 35988641
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chaperone-Driven Degradation of a Misfolded Proinsulin Mutant in Parallel With Restoration of Wild-Type Insulin Secretion.
    Cunningham CN; He K; Arunagiri A; Paton AW; Paton JC; Arvan P; Tsai B
    Diabetes; 2017 Mar; 66(3):741-753. PubMed ID: 28028074
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Proinsulin misfolding and endoplasmic reticulum stress during the development and progression of diabetes.
    Sun J; Cui J; He Q; Chen Z; Arvan P; Liu M
    Mol Aspects Med; 2015 Apr; 42():105-18. PubMed ID: 25579745
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SERCA2 regulates proinsulin processing and processing enzyme maturation in pancreatic beta cells.
    Iida H; Kono T; Lee CC; Krishnan P; Arvin MC; Weaver SA; Jarvela TS; Branco RCS; McLaughlin MR; Bone RN; Tong X; Arvan P; Lindberg I; Evans-Molina C
    Diabetologia; 2023 Nov; 66(11):2042-2061. PubMed ID: 37537395
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Proinsulin misfolding is an early event in the progression to type 2 diabetes.
    Arunagiri A; Haataja L; Pottekat A; Pamenan F; Kim S; Zeltser LM; Paton AW; Paton JC; Tsai B; Itkin-Ansari P; Kaufman RJ; Liu M; Arvan P
    Elife; 2019 Jun; 8():. PubMed ID: 31184302
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SDF2L1 interacts with the ER-associated degradation machinery and retards the degradation of mutant proinsulin in pancreatic β-cells.
    Tiwari A; Schuiki I; Zhang L; Allister EM; Wheeler MB; Volchuk A
    J Cell Sci; 2013 May; 126(Pt 9):1962-8. PubMed ID: 23444373
    [TBL] [Abstract][Full Text] [Related]  

  • 12. COPII-Dependent ER Export: A Critical Component of Insulin Biogenesis and β-Cell ER Homeostasis.
    Fang J; Liu M; Zhang X; Sakamoto T; Taatjes DJ; Jena BP; Sun F; Woods J; Bryson T; Kowluru A; Zhang K; Chen X
    Mol Endocrinol; 2015 Aug; 29(8):1156-69. PubMed ID: 26083833
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Defective Proinsulin Handling Modulates the MHC I Bound Peptidome and Activates the Inflammasome in β-Cells.
    Khilji MS; Faridi P; Pinheiro-Machado E; Hoefner C; Dahlby T; Aranha R; Buus S; Nielsen M; Klusek J; Mandrup-Poulsen T; Pandey K; Purcell AW; Marzec MT
    Biomedicines; 2022 Mar; 10(4):. PubMed ID: 35453564
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inflammatory Cytokines Rewire the Proinsulin Interaction Network in Human Islets.
    Tran DT; Pottekat A; Lee K; Raghunathan M; Loguercio S; Mir SA; Paton AW; Paton JC; Arvan P; Kaufman RJ; Itkin-Ansari P
    J Clin Endocrinol Metab; 2022 Nov; 107(11):3100-3110. PubMed ID: 36017587
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biological behaviors of mutant proinsulin contribute to the phenotypic spectrum of diabetes associated with insulin gene mutations.
    Wang H; Saint-Martin C; Xu J; Ding L; Wang R; Feng W; Liu M; Shu H; Fan Z; Haataja L; Arvan P; Bellanné-Chantelot C; Cui J; Huang Y
    Mol Cell Endocrinol; 2020 Dec; 518():111025. PubMed ID: 32916194
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Endoplasmic Reticulum-Associated Degradation (ERAD) Has a Critical Role in Supporting Glucose-Stimulated Insulin Secretion in Pancreatic β-Cells.
    Hu Y; Gao Y; Zhang M; Deng KY; Singh R; Tian Q; Gong Y; Pan Z; Liu Q; Boisclair YR; Long Q
    Diabetes; 2019 Apr; 68(4):733-746. PubMed ID: 30626610
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bax Inhibitor-1 preserves pancreatic β-cell proteostasis by limiting proinsulin misfolding and programmed cell death.
    Blanc M; Habbouche L; Xiao P; Lebeaupin C; Janona M; Vaillant N; Irondelle M; Gilleron J; Murcy F; Rousseau D; Luci C; Barouillet T; Marchetti S; Lacas-Gervais S; Yvan-Charvet L; Gual P; Cardozo AK; Bailly-Maitre B
    Cell Death Dis; 2024 May; 15(5):334. PubMed ID: 38744890
    [TBL] [Abstract][Full Text] [Related]  

  • 18. FK506-Binding Protein 2 Participates in Proinsulin Folding.
    Hoefner C; Bryde TH; Pihl C; Tiedemann SN; Bresson SE; Hotiana HA; Khilji MS; Santos TD; Puglia M; Pisano P; Majewska M; Durzynska J; Klindt K; Klusek J; Perone MJ; Bucki R; Hägglund PM; Gourdon PE; Gotfryd K; Urbaniak E; Borowiak M; Wierer M; MacDonald PE; Mandrup-Poulsen T; Marzec MT
    Biomolecules; 2023 Jan; 13(1):. PubMed ID: 36671537
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Endoplasmic reticulum-associated degradation of the mouse PC1/3-N222D hypomorph and human PCSK1 mutations contributes to obesity.
    Stijnen P; Brouwers B; Dirkx E; Ramos-Molina B; Van Lommel L; Schuit F; Thorrez L; Declercq J; Creemers JW
    Int J Obes (Lond); 2016 Jun; 40(6):973-81. PubMed ID: 26786350
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Proteasome inhibition alters glucose-stimulated (pro)insulin secretion and turnover in pancreatic {beta}-cells.
    Kitiphongspattana K; Mathews CE; Leiter EH; Gaskins HR
    J Biol Chem; 2005 Apr; 280(16):15727-34. PubMed ID: 15705591
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.