115 related articles for article (PubMed ID: 32259333)
21. Tyrosine 110 plays a critical role in regulating the allosteric inhibition of Campylobacter jejuni dihydrodipicolinate synthase by lysine.
Conly CJ; Skovpen YV; Li S; Palmer DR; Sanders DA
Biochemistry; 2014 Dec; 53(47):7396-406. PubMed ID: 25369463
[TBL] [Abstract][Full Text] [Related]
22. Nanomolar competitive inhibitors of Mycobacterium tuberculosis and Streptomyces coelicolor type II dehydroquinase.
Prazeres VF; Sánchez-Sixto C; Castedo L; Lamb H; Hawkins AR; Riboldi-Tunnicliffe A; Coggins JR; Lapthorn AJ; González-Bello C
ChemMedChem; 2007 Feb; 2(2):194-207. PubMed ID: 17245805
[TBL] [Abstract][Full Text] [Related]
23. Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis.
Gomez GA; Morisseau C; Hammock BD; Christianson DW
Biochemistry; 2004 Apr; 43(16):4716-23. PubMed ID: 15096040
[TBL] [Abstract][Full Text] [Related]
24. Dynamic Modelling Reveals 'Hotspots' on the Pathway to Enzyme-Substrate Complex Formation.
Gordon SE; Weber DK; Downton MT; Wagner J; Perugini MA
PLoS Comput Biol; 2016 Mar; 12(3):e1004811. PubMed ID: 26967332
[TBL] [Abstract][Full Text] [Related]
25. A functionally diverse enzyme superfamily that abstracts the alpha protons of carboxylic acids.
Babbitt PC; Mrachko GT; Hasson MS; Huisman GW; Kolter R; Ringe D; Petsko GA; Kenyon GL; Gerlt JA
Science; 1995 Feb; 267(5201):1159-61. PubMed ID: 7855594
[TBL] [Abstract][Full Text] [Related]
26. Experiences with the shikimate-pathway enzymes as targets for rational drug design.
Coggins JR; Abell C; Evans LB; Frederickson M; Robinson DA; Roszak AW; Lapthorn AP
Biochem Soc Trans; 2003 Jun; 31(Pt 3):548-52. PubMed ID: 12773154
[TBL] [Abstract][Full Text] [Related]
27. Structure of dihydrodipicolinate synthase of Nicotiana sylvestris reveals novel quaternary structure.
Blickling S; Beisel HG; Bozic D; Knäblein J; Laber B; Huber R
J Mol Biol; 1997 Dec; 274(4):608-21. PubMed ID: 9417939
[TBL] [Abstract][Full Text] [Related]
28. Inversion of the roles of the nucleophile and acid/base catalysts in the covalent binding of epoxyalkyl xyloside inhibitor to the catalytic glutamates of endo-1,4-beta-xylanase (XYNII): a molecular dynamics study.
Laitinen T; Rouvinen J; Peräkylä M
Protein Eng; 2000 Apr; 13(4):247-52. PubMed ID: 10810155
[TBL] [Abstract][Full Text] [Related]
29. Discovery of imidazole glycerol phosphate dehydratase inhibitors through 3-D database searching.
Schweitzer BA; Loida PJ; CaJacob CA; Chott RC; Collantes EM; Hegde SG; Mosier PD; Profeta S
Bioorg Med Chem Lett; 2002 Jul; 12(13):1743-6. PubMed ID: 12067551
[TBL] [Abstract][Full Text] [Related]
30. Structural and functional characterization of Staphylococcus aureus dihydrodipicolinate synthase.
Girish TS; Sharma E; Gopal B
FEBS Lett; 2008 Aug; 582(19):2923-30. PubMed ID: 18671976
[TBL] [Abstract][Full Text] [Related]
31. Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis.
Dias MV; Snee WC; Bromfield KM; Payne RJ; Palaninathan SK; Ciulli A; Howard NI; Abell C; Sacchettini JC; Blundell TL
Biochem J; 2011 Jun; 436(3):729-39. PubMed ID: 21410435
[TBL] [Abstract][Full Text] [Related]
32. Purification, characterization and amino acid sequence of a novel enzyme, D-threo-3-hydroxyaspartate dehydratase, from Delftia sp. HT23.
Maeda T; Takeda Y; Murakami T; Yokota A; Wada M
J Biochem; 2010 Dec; 148(6):705-12. PubMed ID: 20843822
[TBL] [Abstract][Full Text] [Related]
33. β-Hydroxyacyl-acyl Carrier Protein Dehydratase (FabZ) from Francisella tularensis and Yersinia pestis: Structure Determination, Enzymatic Characterization, and Cross-Inhibition Studies.
McGillick BE; Kumaran D; Vieni C; Swaminathan S
Biochemistry; 2016 Feb; 55(7):1091-9. PubMed ID: 26818694
[TBL] [Abstract][Full Text] [Related]
34. Progress in type II dehydroquinase inhibitors: from concept to practice.
González-Bello C; Castedo L
Med Res Rev; 2007 Mar; 27(2):177-208. PubMed ID: 17004270
[TBL] [Abstract][Full Text] [Related]
35. Comparative binding energy COMBINE analysis for understanding the binding determinants of type II dehydroquinase inhibitors.
Peón A; Coderch C; Gago F; González-Bello C
ChemMedChem; 2013 May; 8(5):740-7. PubMed ID: 23450741
[TBL] [Abstract][Full Text] [Related]
36. New insights into the mechanism of the Schiff base hydrolysis catalyzed by type I dehydroquinate dehydratase from S. enterica: a theoretical study.
Yao Y; Li ZS
Org Biomol Chem; 2012 Sep; 10(35):7037-44. PubMed ID: 22847490
[TBL] [Abstract][Full Text] [Related]
37. QM/MM simulations identify the determinants of catalytic activity differences between type II dehydroquinase enzymes.
Lence E; van der Kamp MW; González-Bello C; Mulholland AJ
Org Biomol Chem; 2018 Jun; 16(24):4443-4455. PubMed ID: 29767194
[TBL] [Abstract][Full Text] [Related]
38. Inhibitors of lysine biosynthesis as antibacterial agents.
Hutton CA; Southwood TJ; Turner JJ
Mini Rev Med Chem; 2003 Mar; 3(2):115-27. PubMed ID: 12570844
[TBL] [Abstract][Full Text] [Related]
39. A new beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) from Helicobacter pylori: Molecular cloning, enzymatic characterization, and structural modeling.
Liu W; Luo C; Han C; Peng S; Yang Y; Yue J; Shen X; Jiang H
Biochem Biophys Res Commun; 2005 Aug; 333(4):1078-86. PubMed ID: 15967411
[TBL] [Abstract][Full Text] [Related]
40. Designing Irreversible Inhibitors--Worth the Effort?
González-Bello C
ChemMedChem; 2016 Jan; 11(1):22-30. PubMed ID: 26593241
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
