326 related articles for article (PubMed ID: 32259482)
1. Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis.
Wang X; Cai B; Yang X; Sonubi OO; Zheng Z; Ramakrishnan R; Shi H; Valenti L; Pajvani UB; Sandhu J; Infante RE; Radhakrishnan A; Covey DF; Guan KL; Buck J; Levin LR; Tontonoz P; Schwabe RF; Tabas I
Cell Metab; 2020 May; 31(5):969-986.e7. PubMed ID: 32259482
[TBL] [Abstract][Full Text] [Related]
2. Hepatocyte-specific TAZ deletion downregulates p62/ Sqstm1 expression in nonalcoholic steatohepatitis.
Yang X; Sheng S; Du X; Su W; Tian J; Zhao X
Biochem Biophys Res Commun; 2021 Jan; 535():60-65. PubMed ID: 33341674
[TBL] [Abstract][Full Text] [Related]
3. Hepatocyte TAZ/WWTR1 Promotes Inflammation and Fibrosis in Nonalcoholic Steatohepatitis.
Wang X; Zheng Z; Caviglia JM; Corey KE; Herfel TM; Cai B; Masia R; Chung RT; Lefkowitch JH; Schwabe RF; Tabas I
Cell Metab; 2016 Dec; 24(6):848-862. PubMed ID: 28068223
[TBL] [Abstract][Full Text] [Related]
4. TAZ-induced Cybb contributes to liver tumor formation in non-alcoholic steatohepatitis.
Wang X; Zeldin S; Shi H; Zhu C; Saito Y; Corey KE; Osganian SA; Remotti HE; Verna EC; Pajvani UB; Schwabe RF; Tabas I
J Hepatol; 2022 Apr; 76(4):910-920. PubMed ID: 34902531
[TBL] [Abstract][Full Text] [Related]
5. Hepatocyte Stress Increases Expression of Yes-Associated Protein and Transcriptional Coactivator With PDZ-Binding Motif in Hepatocytes to Promote Parenchymal Inflammation and Fibrosis.
Mooring M; Fowl BH; Lum SZC; Liu Y; Yao K; Softic S; Kirchner R; Bernstein A; Singhi AD; Jay DG; Kahn CR; Camargo FD; Yimlamai D
Hepatology; 2020 May; 71(5):1813-1830. PubMed ID: 31505040
[TBL] [Abstract][Full Text] [Related]
6. Circulating indian hedgehog is a marker of the hepatocyte-TAZ pathway in experimental NASH and is elevated in humans with NASH.
Moore MP; Wang X; Shi H; Meroni M; Cherubini A; Ronzoni L; Parks EJ; Ibdah JA; Rector RS; Valenti L; Dongiovanni P; Tabas I
JHEP Rep; 2023 May; 5(5):100716. PubMed ID: 37035456
[TBL] [Abstract][Full Text] [Related]
7. Hepatocyte-targeted siTAZ therapy lowers liver fibrosis in NASH diet-fed chimeric mice with hepatocyte-humanized livers.
Wang X; Moore MP; Shi H; Miyata Y; Donnelly SK; Radiloff DR; Tabas I
Mol Ther Methods Clin Dev; 2023 Dec; 31():101165. PubMed ID: 38144682
[TBL] [Abstract][Full Text] [Related]
8. A Therapeutic Silencing RNA Targeting Hepatocyte TAZ Prevents and Reverses Fibrosis in Nonalcoholic Steatohepatitis in Mice.
Wang X; Sommerfeld MR; Jahn-Hofmann K; Cai B; Filliol A; Remotti HE; Schwabe RF; Kannt A; Tabas I
Hepatol Commun; 2019 Sep; 3(9):1221-1234. PubMed ID: 31497743
[TBL] [Abstract][Full Text] [Related]
9. Hepatocyte nuclear receptor SHP suppresses inflammation and fibrosis in a mouse model of nonalcoholic steatohepatitis.
Zou A; Magee N; Deng F; Lehn S; Zhong C; Zhang Y
J Biol Chem; 2018 Jun; 293(22):8656-8671. PubMed ID: 29666185
[TBL] [Abstract][Full Text] [Related]
10. IRE1A Stimulates Hepatocyte-Derived Extracellular Vesicles That Promote Inflammation in Mice With Steatohepatitis.
Dasgupta D; Nakao Y; Mauer AS; Thompson JM; Sehrawat TS; Liao CY; Krishnan A; Lucien F; Guo Q; Liu M; Xue F; Fukushima M; Katsumi T; Bansal A; Pandey MK; Maiers JL; DeGrado T; Ibrahim SH; Revzin A; Pavelko KD; Barry MA; Kaufman RJ; Malhi H
Gastroenterology; 2020 Oct; 159(4):1487-1503.e17. PubMed ID: 32574624
[TBL] [Abstract][Full Text] [Related]
11. Integrin β
Guo Q; Furuta K; Lucien F; Gutierrez Sanchez LH; Hirsova P; Krishnan A; Kabashima A; Pavelko KD; Madden B; Alhuwaish H; Gao Y; Revzin A; Ibrahim SH
J Hepatol; 2019 Dec; 71(6):1193-1205. PubMed ID: 31433301
[TBL] [Abstract][Full Text] [Related]
12. The transcription factor c-Jun/AP-1 promotes liver fibrosis during non-alcoholic steatohepatitis by regulating Osteopontin expression.
Schulien I; Hockenjos B; Schmitt-Graeff A; Perdekamp MG; Follo M; Thimme R; Hasselblatt P
Cell Death Differ; 2019 Sep; 26(9):1688-1699. PubMed ID: 30778201
[TBL] [Abstract][Full Text] [Related]
13. L-Selectin/CD62L is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men.
Drescher HK; Schippers A; Rosenhain S; Gremse F; Bongiovanni L; Bruin A; Eswaran S; Gallage SU; Pfister D; Szydlowska M; Heikenwalder M; Weiskirchen S; Wagner N; Trautwein C; Weiskirchen R; Kroy DC
Cells; 2020 Apr; 9(5):. PubMed ID: 32365632
[TBL] [Abstract][Full Text] [Related]
14. SKI activates the Hippo pathway via LIMD1 to inhibit cardiac fibroblast activation.
Landry NM; Rattan SG; Filomeno KL; Meier TW; Meier SC; Foran SJ; Meier CF; Koleini N; Fandrich RR; Kardami E; Duhamel TA; Dixon IMC
Basic Res Cardiol; 2021 Apr; 116(1):25. PubMed ID: 33847835
[TBL] [Abstract][Full Text] [Related]
15. Mitochondrial stress activates YAP/TAZ through RhoA oxidation to promote liver injury.
Kwon A; Lee NY; Yu JH; Choi MG; Park J; Koo JH
Cell Death Dis; 2024 Jan; 15(1):51. PubMed ID: 38225223
[TBL] [Abstract][Full Text] [Related]
16. The nonreceptor tyrosine kinase c-Src attenuates SCF(β-TrCP) E3-ligase activity abrogating Taz proteasomal degradation.
Shanzer M; Adler J; Ricardo-Lax I; Reuven N; Shaul Y
Proc Natl Acad Sci U S A; 2017 Feb; 114(7):1678-1683. PubMed ID: 28154141
[TBL] [Abstract][Full Text] [Related]
17. Cholesterol accumulation in hepatocytes mediates IRE1/p38 branch of endoplasmic reticulum stress to promote nonalcoholic steatohepatitis.
Sozen E; Demirel-Yalciner T; Sari D; Ozer NK
Free Radic Biol Med; 2022 Oct; 191():1-7. PubMed ID: 35995397
[TBL] [Abstract][Full Text] [Related]
18. Maladaptive regeneration - the reawakening of developmental pathways in NASH and fibrosis.
Zhu C; Tabas I; Schwabe RF; Pajvani UB
Nat Rev Gastroenterol Hepatol; 2021 Feb; 18(2):131-142. PubMed ID: 33051603
[TBL] [Abstract][Full Text] [Related]
19. Increased expression of yes-associated protein/YAP and transcriptional coactivator with PDZ-binding motif/TAZ activates intestinal fibroblasts to promote intestinal obstruction in Crohn's disease.
Ou W; Xu W; Liu F; Guo Y; Huang Z; Feng T; Liu CY; Du P
EBioMedicine; 2021 Jul; 69():103452. PubMed ID: 34186485
[TBL] [Abstract][Full Text] [Related]
20. Hepatocyte free cholesterol lipotoxicity results from JNK1-mediated mitochondrial injury and is HMGB1 and TLR4-dependent.
Gan LT; Van Rooyen DM; Koina ME; McCuskey RS; Teoh NC; Farrell GC
J Hepatol; 2014 Dec; 61(6):1376-84. PubMed ID: 25064435
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]