BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

189 related articles for article (PubMed ID: 32268084)

  • 1. Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells.
    Drainas AP; Lambuta RA; Ivanova I; Serçin Ö; Sarropoulos I; Smith ML; Efthymiopoulos T; Raeder B; Stütz AM; Waszak SM; Mardin BR; Korbel JO
    Cell Rep; 2020 Apr; 31(1):107465. PubMed ID: 32268084
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability.
    Fagan-Solis KD; Simpson DA; Kumar RJ; Martelotto LG; Mose LE; Rashid NU; Ho AY; Powell SN; Wen YH; Parker JS; Reis-Filho JS; Petrini JHJ; Gupta GP
    Cell Rep; 2020 Feb; 30(5):1385-1399.e7. PubMed ID: 32023457
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance.
    Bowden AR; Morales-Juarez DA; Sczaniecka-Clift M; Agudo MM; Lukashchuk N; Thomas JC; Jackson SP
    Elife; 2020 May; 9():. PubMed ID: 32441252
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expression of the Long Noncoding RNA DINO in Human Papillomavirus-Positive Cervical Cancer Cells Reactivates the Dormant TP53 Tumor Suppressor through ATM/CHK2 Signaling.
    Sharma S; Munger K
    mBio; 2020 Jun; 11(3):. PubMed ID: 32546626
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tumor suppressor ataxia telangiectasia mutated functions downstream of TGF-β1 in orchestrating profibrotic responses.
    Overstreet JM; Samarakoon R; Cardona-Grau D; Goldschmeding R; Higgins PJ
    FASEB J; 2015 Apr; 29(4):1258-68. PubMed ID: 25480384
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TNF-α modulates genome-wide redistribution of ΔNp63α/TAp73 and NF-κB cREL interactive binding on TP53 and AP-1 motifs to promote an oncogenic gene program in squamous cancer.
    Si H; Lu H; Yang X; Mattox A; Jang M; Bian Y; Sano E; Viadiu H; Yan B; Yau C; Ng S; Lee SK; Romano RA; Davis S; Walker RL; Xiao W; Sun H; Wei L; Sinha S; Benz CC; Stuart JM; Meltzer PS; Van Waes C; Chen Z
    Oncogene; 2016 Nov; 35(44):5781-5794. PubMed ID: 27132513
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The TP53-activated E3 ligase RNF144B is a tumour suppressor that prevents genomic instability.
    Abad E; Sandoz J; Romero G; Zadra I; Urgel-Solas J; Borredat P; Kourtis S; Ortet L; Martínez CM; Weghorn D; Sdelci S; Janic A
    J Exp Clin Cancer Res; 2024 Apr; 43(1):127. PubMed ID: 38685100
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TGFβ Promotes Genomic Instability after Loss of RUNX3.
    Krishnan V; Chong YL; Tan TZ; Kulkarni M; Bin Rahmat MB; Tay LS; Sankar H; Jokhun DS; Ganesan A; Chuang LSH; Voon DC; Shivashankar GV; Thiery JP; Ito Y
    Cancer Res; 2018 Jan; 78(1):88-102. PubMed ID: 29074538
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Combined poly-ADP ribose polymerase and ataxia-telangiectasia mutated/Rad3-related inhibition targets ataxia-telangiectasia mutated-deficient lung cancer cells.
    Jette NR; Radhamani S; Arthur G; Ye R; Goutam S; Bolyos A; Petersen LF; Bose P; Bebb DG; Lees-Miller SP
    Br J Cancer; 2019 Oct; 121(7):600-610. PubMed ID: 31481733
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DNA Damage Activates TGF-β Signaling via ATM-c-Cbl-Mediated Stabilization of the Type II Receptor TβRII.
    Li Y; Liu Y; Chiang YJ; Huang F; Li Y; Li X; Ning Y; Zhang W; Deng H; Chen YG
    Cell Rep; 2019 Jul; 28(3):735-745.e4. PubMed ID: 31315051
    [TBL] [Abstract][Full Text] [Related]  

  • 11. High Expressions of CUL4A and TP53 in Colorectal Cancer Predict Poor Survival.
    Li C; Bu J; Liao Y; Zhang J; Han J; Zhang H; Xing H; Li Z; Wu H; Liang L; Wang M; Qin W; Yang T
    Cell Physiol Biochem; 2018; 51(6):2829-2842. PubMed ID: 30562757
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cullin-7 (CUL7) is overexpressed in glioma cells and promotes tumorigenesis via NF-κB activation.
    Xu J; Zhang Z; Qian M; Wang S; Qiu W; Chen Z; Sun Z; Xiong Y; Wang C; Sun X; Zhao R; Xue H; Li G
    J Exp Clin Cancer Res; 2020 Apr; 39(1):59. PubMed ID: 32252802
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Association of Tumor Protein p53 and Ataxia-Telangiectasia Mutated Comutation With Response to Immune Checkpoint Inhibitors and Mortality in Patients With Non-Small Cell Lung Cancer.
    Chen Y; Chen G; Li J; Huang YY; Li Y; Lin J; Chen LZ; Lu JP; Wang YQ; Wang CX; Pan LK; Xia XF; Yi X; Chen CB; Zheng XW; Guo ZQ; Pan JJ
    JAMA Netw Open; 2019 Sep; 2(9):e1911895. PubMed ID: 31539077
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Loss of the tumor suppressor BIN1 enables ATM Ser/Thr kinase activation by the nuclear protein E2F1 and renders cancer cells resistant to cisplatin.
    Folk WP; Kumari A; Iwasaki T; Pyndiah S; Johnson JC; Cassimere EK; Abdulovic-Cui AL; Sakamuro D
    J Biol Chem; 2019 Apr; 294(14):5700-5719. PubMed ID: 30733337
    [TBL] [Abstract][Full Text] [Related]  

  • 15. p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM.
    Song H; Hollstein M; Xu Y
    Nat Cell Biol; 2007 May; 9(5):573-80. PubMed ID: 17417627
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Oxidative stress shapes breast cancer phenotype through chronic activation of ATM-dependent signaling.
    Alpay M; Backman LR; Cheng X; Dukel M; Kim WJ; Ai L; Brown KD
    Breast Cancer Res Treat; 2015 May; 151(1):75-87. PubMed ID: 25862169
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The depletion of ATM inhibits colon cancer proliferation and migration via B56γ2-mediated Chk1/p53/CD44 cascades.
    Liu R; Tang J; Ding C; Liang W; Zhang L; Chen T; Xiong Y; Dai X; Li W; Xu Y; Hu J; Lu L; Liao W; Lu X
    Cancer Lett; 2017 Apr; 390():48-57. PubMed ID: 28093285
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Involvement of Atm and Trp53 in neural cell loss due to Terf2 inactivation during mouse brain development.
    Kim J; Choi I; Lee Y
    Histochem Cell Biol; 2017 Nov; 148(5):489-501. PubMed ID: 28620865
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The cyclin E regulator cullin 3 prevents mouse hepatic progenitor cells from becoming tumor-initiating cells.
    Kossatz U; Breuhahn K; Wolf B; Hardtke-Wolenski M; Wilkens L; Steinemann D; Singer S; Brass F; Kubicka S; Schlegelberger B; Schirmacher P; Manns MP; Singer JD; Malek NP
    J Clin Invest; 2010 Nov; 120(11):3820-33. PubMed ID: 20978349
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ataxia telangiectasia mutated-deficient B-cell chronic lymphocytic leukemia occurs in pregerminal center cells and results in defective damage response and unrepaired chromosome damage.
    Stankovic T; Stewart GS; Fegan C; Biggs P; Last J; Byrd PJ; Keenan RD; Moss PA; Taylor AM
    Blood; 2002 Jan; 99(1):300-9. PubMed ID: 11756185
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.