277 related articles for article (PubMed ID: 32268371)
1. Understanding heterogeneity of fetal hemoglobin induction through comparative analysis of F and A erythroblasts.
Khandros E; Huang P; Peslak SA; Sharma M; Abdulmalik O; Giardine BM; Zhang Z; Keller CA; Hardison RC; Blobel GA
Blood; 2020 May; 135(22):1957-1968. PubMed ID: 32268371
[TBL] [Abstract][Full Text] [Related]
2. Metformin induces FOXO3-dependent fetal hemoglobin production in human primary erythroid cells.
Zhang Y; Paikari A; Sumazin P; Ginter Summarell CC; Crosby JR; Boerwinkle E; Weiss MJ; Sheehan VA
Blood; 2018 Jul; 132(3):321-333. PubMed ID: 29884740
[TBL] [Abstract][Full Text] [Related]
3. EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression.
Renneville A; Van Galen P; Canver MC; McConkey M; Krill-Burger JM; Dorfman DM; Holson EB; Bernstein BE; Orkin SH; Bauer DE; Ebert BL
Blood; 2015 Oct; 126(16):1930-9. PubMed ID: 26320100
[TBL] [Abstract][Full Text] [Related]
4. Pomalidomide and lenalidomide regulate erythropoiesis and fetal hemoglobin production in human CD34+ cells.
Moutouh-de Parseval LA; Verhelle D; Glezer E; Jensen-Pergakes K; Ferguson GD; Corral LG; Morris CL; Muller G; Brady H; Chan K
J Clin Invest; 2008 Jan; 118(1):248-58. PubMed ID: 18064299
[TBL] [Abstract][Full Text] [Related]
5. Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.
Sankaran VG; Menne TF; Xu J; Akie TE; Lettre G; Van Handel B; Mikkola HK; Hirschhorn JN; Cantor AB; Orkin SH
Science; 2008 Dec; 322(5909):1839-42. PubMed ID: 19056937
[TBL] [Abstract][Full Text] [Related]
6. A zinc-finger transcriptional activator designed to interact with the gamma-globin gene promoters enhances fetal hemoglobin production in primary human adult erythroblasts.
Wilber A; Tschulena U; Hargrove PW; Kim YS; Persons DA; Barbas CF; Nienhuis AW
Blood; 2010 Apr; 115(15):3033-41. PubMed ID: 20190190
[TBL] [Abstract][Full Text] [Related]
7. The proinflammatory cytokine GM-CSF downregulates fetal hemoglobin expression by attenuating the cAMP-dependent pathway in sickle cell disease.
Ikuta T; Adekile AD; Gutsaeva DR; Parkerson JB; Yerigenahally SD; Clair B; Kutlar A; Odo N; Head CA
Blood Cells Mol Dis; 2011 Dec; 47(4):235-42. PubMed ID: 21945571
[TBL] [Abstract][Full Text] [Related]
8. SIRT1 activates the expression of fetal hemoglobin genes.
Dai Y; Chen T; Ijaz H; Cho EH; Steinberg MH
Am J Hematol; 2017 Nov; 92(11):1177-1186. PubMed ID: 28776729
[TBL] [Abstract][Full Text] [Related]
9. BCL11A Down-Regulation Induces γ-Globin in Human β-Thalassemia Major Erythroid Cells.
Li J; Lai Y; Shi L
Hemoglobin; 2018 Jul; 42(4):225-230. PubMed ID: 30821197
[TBL] [Abstract][Full Text] [Related]
10. Pharmacological Induction of Human Fetal Globin Gene in Hydroxyurea-Resistant Primary Adult Erythroid Cells.
Chou YC; Chen RL; Lai ZS; Song JS; Chao YS; Shen CK
Mol Cell Biol; 2015 Jul; 35(14):2541-53. PubMed ID: 25986606
[TBL] [Abstract][Full Text] [Related]
11. SOX6 Downregulation Induces
Li J; Lai Y; Luo J; Luo L; Liu R; Liu Z; Zhao W
Biomed Res Int; 2017; 2017():9496058. PubMed ID: 29333458
[TBL] [Abstract][Full Text] [Related]
12. Phenotypic-screening generates active novel fetal globin-inducers that downregulate Bcl11a in a monkey model.
Makino T; Haruyama M; Katayama K; Terashima H; Tsunemi T; Miyazaki K; Terakawa M; Yamashiro K; Yoshioka R; Maeda H
Biochem Pharmacol; 2020 Jan; 171():113717. PubMed ID: 31751536
[TBL] [Abstract][Full Text] [Related]
13. Reactivation of Fetal Hemoglobin for Treating β-Thalassemia and Sickle Cell Disease.
Cui S; Engel JD
Adv Exp Med Biol; 2017; 1013():177-202. PubMed ID: 29127681
[TBL] [Abstract][Full Text] [Related]
14. A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition.
Traxler EA; Yao Y; Wang YD; Woodard KJ; Kurita R; Nakamura Y; Hughes JR; Hardison RC; Blobel GA; Li C; Weiss MJ
Nat Med; 2016 Sep; 22(9):987-90. PubMed ID: 27525524
[TBL] [Abstract][Full Text] [Related]
15. Acyclovir induces fetal hemoglobin via downregulation of γ-globin repressors, BCL11A and SOX6 trans-acting factors.
Ali H; Khan F; Ghulam Musharraf S
Biochem Pharmacol; 2021 Aug; 190():114612. PubMed ID: 34010599
[TBL] [Abstract][Full Text] [Related]
16. Hydroxyurea differentially modulates activator and repressors of γ-globin gene in erythroblasts of responsive and non-responsive patients with sickle cell disease in correlation with Index of Hydroxyurea Responsiveness.
Zhu X; Hu T; Ho MH; Wang Y; Yu M; Patel N; Pi W; Choi JH; Xu H; Ganapathy V; Kutlar F; Kutlar A; Tuan D
Haematologica; 2017 Dec; 102(12):1995-2004. PubMed ID: 28971909
[TBL] [Abstract][Full Text] [Related]
17. Fetal hemoglobin silencing in humans.
Oneal PA; Gantt NM; Schwartz JD; Bhanu NV; Lee YT; Moroney JW; Reed CH; Schechter AN; Luban NL; Miller JL
Blood; 2006 Sep; 108(6):2081-6. PubMed ID: 16735596
[TBL] [Abstract][Full Text] [Related]
18. High fetal hemoglobin production in sickle cell anemia in the eastern province of Saudi Arabia is genetically determined.
Miller BA; Salameh M; Ahmed M; Wainscoat J; Antognetti G; Orkin S; Weatherall D; Nathan DG
Blood; 1986 May; 67(5):1404-10. PubMed ID: 2421808
[TBL] [Abstract][Full Text] [Related]
19. Interferon-gamma modulates fetal hemoglobin synthesis in sickle cell anemia and thalassemia.
Miller BA; Olivieri N; Hope SM; Faller DV; Perrine SP
J Interferon Res; 1990 Aug; 10(4):357-66. PubMed ID: 1700029
[TBL] [Abstract][Full Text] [Related]
20. Cilostazol-mediated reversion of γ-globin silencing is associated with a high level of HbF production: A potential therapeutic candidate for β-globin disorders.
Ali H; Khan F; Musharraf SG
Biomed Pharmacother; 2021 Oct; 142():112058. PubMed ID: 34426256
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
