BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

238 related articles for article (PubMed ID: 32271748)

  • 1. Crosslinking-guided geometry of a complete CXC receptor-chemokine complex and the basis of chemokine subfamily selectivity.
    Ngo T; Stephens BS; Gustavsson M; Holden LG; Abagyan R; Handel TM; Kufareva I
    PLoS Biol; 2020 Apr; 18(4):e3000656. PubMed ID: 32271748
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential activity and selectivity of N-terminal modified CXCL12 chemokines at the CXCR4 and ACKR3 receptors.
    Jaracz-Ros A; Bernadat G; Cutolo P; Gallego C; Gustavsson M; Cecon E; Baleux F; Kufareva I; Handel TM; Bachelerie F; Levoye A
    J Leukoc Biol; 2020 Jun; 107(6):1123-1135. PubMed ID: 32374043
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The chemokine X-factor: Structure-function analysis of the CXC motif at CXCR4 and ACKR3.
    Wedemeyer MJ; Mahn SA; Getschman AE; Crawford KS; Peterson FC; Marchese A; McCorvy JD; Volkman BF
    J Biol Chem; 2020 Oct; 295(40):13927-13939. PubMed ID: 32788219
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural basis for chemokine recognition by a G protein-coupled receptor and implications for receptor activation.
    Ziarek JJ; Kleist AB; London N; Raveh B; Montpas N; Bonneterre J; St-Onge G; DiCosmo-Ponticello CJ; Koplinski CA; Roy I; Stephens B; Thelen S; Veldkamp CT; Coffman FD; Cohen MC; Dwinell MB; Thelen M; Peterson FC; Heveker N; Volkman BF
    Sci Signal; 2017 Mar; 10(471):. PubMed ID: 28325822
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functional anatomy of the full-length CXCR4-CXCL12 complex systematically dissected by quantitative model-guided mutagenesis.
    Stephens BS; Ngo T; Kufareva I; Handel TM
    Sci Signal; 2020 Jul; 13(640):. PubMed ID: 32665413
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stoichiometry and geometry of the CXC chemokine receptor 4 complex with CXC ligand 12: molecular modeling and experimental validation.
    Kufareva I; Stephens BS; Holden LG; Qin L; Zhao C; Kawamura T; Abagyan R; Handel TM
    Proc Natl Acad Sci U S A; 2014 Dec; 111(50):E5363-72. PubMed ID: 25468967
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interaction of chemokine receptor CXCR4 in monomeric and dimeric state with its endogenous ligand CXCL12: coarse-grained simulations identify differences.
    Cutolo P; Basdevant N; Bernadat G; Bachelerie F; Ha-Duong T
    J Biomol Struct Dyn; 2017 Feb; 35(2):399-412. PubMed ID: 26813575
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Kinetics of CXCL12 binding to atypical chemokine receptor 3 reveal a role for the receptor N terminus in chemokine binding.
    Gustavsson M; Dyer DP; Zhao C; Handel TM
    Sci Signal; 2019 Sep; 12(598):. PubMed ID: 31506383
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine.
    Qin L; Kufareva I; Holden LG; Wang C; Zheng Y; Zhao C; Fenalti G; Wu H; Han GW; Cherezov V; Abagyan R; Stevens RC; Handel TM
    Science; 2015 Mar; 347(6226):1117-22. PubMed ID: 25612609
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Heparin oligosaccharides inhibit chemokine (CXC motif) ligand 12 (CXCL12) cardioprotection by binding orthogonal to the dimerization interface, promoting oligomerization, and competing with the chemokine (CXC motif) receptor 4 (CXCR4) N terminus.
    Ziarek JJ; Veldkamp CT; Zhang F; Murray NJ; Kartz GA; Liang X; Su J; Baker JE; Linhardt RJ; Volkman BF
    J Biol Chem; 2013 Jan; 288(1):737-46. PubMed ID: 23148226
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Signal transmission through the CXC chemokine receptor 4 (CXCR4) transmembrane helices.
    Wescott MP; Kufareva I; Paes C; Goodman JR; Thaker Y; Puffer BA; Berdougo E; Rucker JB; Handel TM; Doranz BJ
    Proc Natl Acad Sci U S A; 2016 Aug; 113(35):9928-33. PubMed ID: 27543332
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural basis of the interaction between chemokine stromal cell-derived factor-1/CXCL12 and its G-protein-coupled receptor CXCR4.
    Kofuku Y; Yoshiura C; Ueda T; Terasawa H; Hirai T; Tominaga S; Hirose M; Maeda Y; Takahashi H; Terashima Y; Matsushima K; Shimada I
    J Biol Chem; 2009 Dec; 284(50):35240-50. PubMed ID: 19837984
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sulfopeptide probes of the CXCR4/CXCL12 interface reveal oligomer-specific contacts and chemokine allostery.
    Ziarek JJ; Getschman AE; Butler SJ; Taleski D; Stephens B; Kufareva I; Handel TM; Payne RJ; Volkman BF
    ACS Chem Biol; 2013 Sep; 8(9):1955-63. PubMed ID: 23802178
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dual targeting of the chemokine receptors CXCR4 and ACKR3 with novel engineered chemokines.
    Hanes MS; Salanga CL; Chowdry AB; Comerford I; McColl SR; Kufareva I; Handel TM
    J Biol Chem; 2015 Sep; 290(37):22385-97. PubMed ID: 26216880
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12.
    Veldkamp CT; Seibert C; Peterson FC; De la Cruz NB; Haugner JC; Basnet H; Sakmar TP; Volkman BF
    Sci Signal; 2008 Sep; 1(37):ra4. PubMed ID: 18799424
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural basis of the interactions between CXCR4 and CXCL12/SDF-1 revealed by theoretical approaches.
    Xu L; Li Y; Sun H; Li D; Hou T
    Mol Biosyst; 2013 Aug; 9(8):2107-17. PubMed ID: 23702796
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Epithelial chemokine CXCL14 synergizes with CXCL12
    Collins PJ; McCully ML; Martínez-Muñoz L; Santiago C; Wheeldon J; Caucheteux S; Thelen S; Cecchinato V; Laufer JM; Purvanov V; Monneau YR; Lortat-Jacob H; Legler DF; Uguccioni M; Thelen M; Piguet V; Mellado M; Moser B
    FASEB J; 2017 Jul; 31(7):3084-3097. PubMed ID: 28360196
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural determinants of ubiquitin-CXC chemokine receptor 4 interaction.
    Saini V; Marchese A; Tang WJ; Majetschak M
    J Biol Chem; 2011 Dec; 286(51):44145-44152. PubMed ID: 22039044
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Development of novel CXC chemokine receptor 7 (CXCR7) ligands: selectivity switch from CXCR4 antagonists with a cyclic pentapeptide scaffold.
    Oishi S; Kuroyanagi T; Kubo T; Montpas N; Yoshikawa Y; Misu R; Kobayashi Y; Ohno H; Heveker N; Furuya T; Fujii N
    J Med Chem; 2015 Jul; 58(13):5218-25. PubMed ID: 26042340
    [TBL] [Abstract][Full Text] [Related]  

  • 20. G protein‑mediated EGFR transactivation is a common mechanism through which the CXCL12 receptors, CXCR4 and CXCR7, control human cancer cell migration.
    Zieger-Naumann K; Kuhl F; Engele J
    Oncol Rep; 2024 Feb; 51(2):. PubMed ID: 38099418
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.