BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 32275415)

  • 1. MymA Bioactivated Thioalkylbenzoxazole Prodrug Family Active against
    Moure AL; Narula G; Sorrentino F; Bojang A; Tsui CKM; Sao Emani C; Porras-De Francisco E; Díaz B; Rebollo-López MJ; Torres-Gómez PA; López-Román EM; Camino I; Casado Castro P; Guijarro López L; Ortega F; Ballell L; Barros-Aguirre D; Remuiñán Blanco M; Av-Gay Y
    J Med Chem; 2020 May; 63(9):4732-4748. PubMed ID: 32275415
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Searching for New Leads for Tuberculosis: Design, Synthesis, and Biological Evaluation of Novel 2-Quinolin-4-yloxyacetamides.
    Pitta E; Rogacki MK; Balabon O; Huss S; Cunningham F; Lopez-Roman EM; Joossens J; Augustyns K; Ballell L; Bates RH; Van der Veken P
    J Med Chem; 2016 Jul; 59(14):6709-28. PubMed ID: 27348630
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis, anti-HIV and antitubercular activities of lamivudine prodrugs.
    Sriram D; Yogeeswari P; Gopal G
    Eur J Med Chem; 2005 Dec; 40(12):1373-6. PubMed ID: 16129516
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Benzofuroxan Derivatives as Potent Agents against Multidrug-Resistant Mycobacterium tuberculosis.
    Fernandes GFS; Campos DL; Da Silva IC; Prates JLB; Pavan AR; Pavan FR; Dos Santos JL
    ChemMedChem; 2021 Apr; 16(8):1268-1282. PubMed ID: 33410233
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of Leubethanol derivatives and evaluation against Mycobacterium tuberculosis.
    Perez-Meseguer J; Del Olmo E; Alanis-Garza B; Escarcena R; Garza-González E; Salazar-Aranda R; Feliciano AS; de Torres NW
    Bioorg Med Chem; 2012 Jul; 20(13):4155-63. PubMed ID: 22626551
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Baeyer-Villiger Monooxygenases EthA and MymA Are Required for Activation of Replicating and Non-replicating Mycobacterium tuberculosis Inhibitors.
    Grant SS; Wellington S; Kawate T; Desjardins CA; Silvis MR; Wivagg C; Thompson M; Gordon K; Kazyanskaya E; Nietupski R; Haseley N; Iwase N; Earl AM; Fitzgerald M; Hung DT
    Cell Chem Biol; 2016 Jun; 23(6):666-77. PubMed ID: 27321573
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-activity relationships of antitubercular nitroimidazoles. 3. Exploration of the linker and lipophilic tail of ((s)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl)-(4-trifluoromethoxybenzyl)amine (6-amino PA-824).
    Cherian J; Choi I; Nayyar A; Manjunatha UH; Mukherjee T; Lee YS; Boshoff HI; Singh R; Ha YH; Goodwin M; Lakshminarayana SB; Niyomrattanakit P; Jiricek J; Ravindran S; Dick T; Keller TH; Dartois V; Barry CE
    J Med Chem; 2011 Aug; 54(16):5639-59. PubMed ID: 21755942
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A prodrug approach for improving antituberculosis activity of potent Mycobacterium tuberculosis type II dehydroquinase inhibitors.
    Tizón L; Otero JM; Prazeres VF; Llamas-Saiz AL; Fox GC; van Raaij MJ; Lamb H; Hawkins AR; Ainsa JA; Castedo L; González-Bello C
    J Med Chem; 2011 Sep; 54(17):6063-84. PubMed ID: 21780742
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, and biological evaluation of novel 4H-chromen-4-one derivatives as antituberculosis agents against multidrug-resistant tuberculosis.
    Zhao W; Wang B; Liu Y; Fu L; Sheng L; Zhao H; Lu Y; Zhang D
    Eur J Med Chem; 2020 Mar; 189():112075. PubMed ID: 31986405
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Docking- and pharmacophore-based virtual screening for the identification of novel Mycobacterium tuberculosis protein tyrosine phosphatase B (MptpB) inhibitor with a thiobarbiturate scaffold.
    Zhang D; Lin Y; Chen X; Zhao W; Chen D; Gao M; Wang Q; Wang B; Huang H; Lu Y; Lu Y
    Bioorg Chem; 2019 Apr; 85():229-239. PubMed ID: 30641319
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, and biological evaluation of indole-2-carboxamides: a promising class of antituberculosis agents.
    Kondreddi RR; Jiricek J; Rao SP; Lakshminarayana SB; Camacho LR; Rao R; Herve M; Bifani P; Ma NL; Kuhen K; Goh A; Chatterjee AK; Dick T; Diagana TT; Manjunatha UH; Smith PW
    J Med Chem; 2013 Nov; 56(21):8849-59. PubMed ID: 24090347
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and antituberculosis activity of novel mefloquine-isoxazole carboxylic esters as prodrugs.
    Mao J; Yuan H; Wang Y; Wan B; Pak D; He R; Franzblau SG
    Bioorg Med Chem Lett; 2010 Feb; 20(3):1263-8. PubMed ID: 20022500
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antimycobacterial activity of pyrazinoate prodrugs in replicating and non-replicating Mycobacterium tuberculosis.
    Segretti ND; Simões CK; Corrêa MF; Felli VMA; Miyata M; Cho SH; Franzblau SG; Fernandes JPDS
    Tuberculosis (Edinb); 2016 Jul; 99():11-16. PubMed ID: 27449999
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Aminopyrazolo[1,5-a]pyrimidines as potential inhibitors of Mycobacterium tuberculosis: Structure activity relationships and ADME characterization.
    Soares de Melo C; Feng TS; van der Westhuyzen R; Gessner RK; Street LJ; Morgans GL; Warner DF; Moosa A; Naran K; Lawrence N; Boshoff HI; Barry CE; Harris CJ; Gordon R; Chibale K
    Bioorg Med Chem; 2015 Nov; 23(22):7240-50. PubMed ID: 26522089
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Benzoheterocyclic Oxime Carbamates Active against
    van der Westhuyzen R; Mabhula A; Njaria PM; Müller R; Ngumbu Muhunga D; Taylor D; Lawrence N; Njoroge M; Brunschwig C; Moosa A; Singh V; Rao SPS; Manjunatha UH; Smith PW; Warner DF; Street LJ; Chibale K
    J Med Chem; 2021 Jul; 64(13):9444-9457. PubMed ID: 34138573
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development of benzo[d]oxazol-2(3H)-ones derivatives as novel inhibitors of Mycobacterium tuberculosis InhA.
    Pedgaonkar GS; Sridevi JP; Jeankumar VU; Saxena S; Devi PB; Renuka J; Yogeeswari P; Sriram D
    Bioorg Med Chem; 2014 Nov; 22(21):6134-45. PubMed ID: 25282650
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Preparation and in vitro evaluation of benzylsulfanyl benzoxazole derivatives as potential antituberculosis agents.
    Klimesová V; Kocí J; Waisser K; Kaustová J; Möllmann U
    Eur J Med Chem; 2009 May; 44(5):2286-93. PubMed ID: 18694614
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lipophilic pyrazinoic acid amide and ester prodrugs stability, activation and activity against M. tuberculosis.
    Simões MF; Valente E; Gómez MJ; Anes E; Constantino L
    Eur J Pharm Sci; 2009 Jun; 37(3-4):257-63. PubMed ID: 19491013
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Potential tuberculostatic agents: micelle-forming copolymer poly(ethylene glycol)-poly(aspartic acid) prodrug with isoniazid.
    Silva M; Lara AS; Leite CQ; Ferreira EI
    Arch Pharm (Weinheim); 2001 Jun; 334(6):189-93. PubMed ID: 11475908
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Xanthates: Metabolism by Flavoprotein-Containing Monooxygenases and Antimycobacterial Activity.
    Yanev SG; Stoyanova TD; Valcheva VV; Ortiz de Montellano PR
    Drug Metab Dispos; 2018 Aug; 46(8):1091-1095. PubMed ID: 29777023
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.