BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

361 related articles for article (PubMed ID: 32277923)

  • 1. Functional changes of the liver in the absence of growth hormone (GH) action - Proteomic and metabolomic insights from a GH receptor deficient pig model.
    Riedel EO; Hinrichs A; Kemter E; Dahlhoff M; Backman M; Rathkolb B; Prehn C; Adamski J; Renner S; Blutke A; de Angelis MH; Bidlingmaier M; Schopohl J; Arnold GJ; Fröhlich T; Wolf E
    Mol Metab; 2020 Jun; 36():100978. PubMed ID: 32277923
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liver.
    Hinrichs A; Kessler B; Kurome M; Blutke A; Kemter E; Bernau M; Scholz AM; Rathkolb B; Renner S; Bultmann S; Leonhardt H; de Angelis MH; Nagashima H; Hoeflich A; Blum WF; Bidlingmaier M; Wanke R; Dahlhoff M; Wolf E
    Mol Metab; 2018 May; 11():113-128. PubMed ID: 29678421
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effects of GHR Deficiency and Juvenile Hypoglycemia on Immune Cells of a Porcine Model for Laron Syndrome.
    Schilloks MC; Giese IM; Hinrichs A; Korbonits L; Hauck SM; Wolf E; Deeg CA
    Biomolecules; 2023 Mar; 13(4):. PubMed ID: 37189345
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural and proteomic repercussions of growth hormone receptor deficiency on the pituitary gland: Lessons from a translational pig model.
    Shashikadze B; Franzmeier S; Hofmann I; Kraetzl M; Flenkenthaler F; Blutke A; Fröhlich T; Wolf E; Hinrichs A
    J Neuroendocrinol; 2023 Apr; ():e13277. PubMed ID: 37160285
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Direct and systemic actions of growth hormone receptor (GHR)-signaling on hepatic glycolysis, de novo lipogenesis and insulin sensitivity, associated with steatosis.
    Vázquez-Borrego MC; Del Río-Moreno M; Pyatkov M; Sarmento-Cabral A; Mahmood M; Pelke N; Wnek M; Cordoba-Chacon J; Waxman DJ; Puchowicz MA; McGuinness OP; Kineman RD
    Metabolism; 2023 Jul; 144():155589. PubMed ID: 37182789
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Generation of a miniature pig disease model for human Laron syndrome.
    Cui D; Li F; Li Q; Li J; Zhao Y; Hu X; Zhang R; Li N
    Sci Rep; 2015 Oct; 5():15603. PubMed ID: 26511035
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse).
    Zhou Y; Xu BC; Maheshwari HG; He L; Reed M; Lozykowski M; Okada S; Cataldo L; Coschigamo K; Wagner TE; Baumann G; Kopchick JJ
    Proc Natl Acad Sci U S A; 1997 Nov; 94(24):13215-20. PubMed ID: 9371826
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metabolic effects of reduced growth hormone action in fatty liver disease.
    Rufinatscha K; Ress C; Folie S; Haas S; Salzmann K; Moser P; Dobner J; Weiss G; Iruzubieta P; Arias-Loste MT; Crespo J; Tilg H; Kaser S
    Hepatol Int; 2018 Sep; 12(5):474-481. PubMed ID: 30206761
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Growth hormone insensitivity and adipose tissue: tissue morphology and transcriptome analyses in pigs and humans.
    Young JA; Hinrichs A; Bell S; Geitgey DK; Hume-Rivera D; Bounds A; Soneson M; Laron Z; Yaron-Shaminsky D; Wolf E; List EO; Kopchick JJ; Berryman DE
    Pituitary; 2023 Dec; 26(6):660-674. PubMed ID: 37747600
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Growth hormone (GH) receptor knockout mice reveal actions of GH in lung development.
    Beyea JA; Sawicki G; Olson DM; List E; Kopchick JJ; Harvey S
    Proteomics; 2006 Jan; 6(1):341-8. PubMed ID: 16287172
    [TBL] [Abstract][Full Text] [Related]  

  • 11. GH directly inhibits steatosis and liver injury in a sex-dependent and IGF1-independent manner.
    Sarmento-Cabral A; Del Rio-Moreno M; Vazquez-Borrego MC; Mahmood M; Gutierrez-Casado E; Pelke N; Guzman G; Subbaiah PV; Cordoba-Chacon J; Yakar S; Kineman RD
    J Endocrinol; 2021 Jan; 248(1):31-44. PubMed ID: 33112796
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Generation of GHR-modified pigs as Laron syndrome models via a dual-sgRNAs/Cas9 system and somatic cell nuclear transfer.
    Yu H; Long W; Zhang X; Xu K; Guo J; Zhao H; Li H; Qing Y; Pan W; Jia B; Zhao HY; Huang X; Wei HJ
    J Transl Med; 2018 Feb; 16(1):41. PubMed ID: 29482569
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Distinct cytoplasmic domains of the growth hormone receptor are required for glucocorticoid- and phorbol ester-induced decreases in growth hormone (GH) binding. These domains are different from that reported for GH-induced receptor internalization.
    King AP; Tseng MJ; Logsdon CD; Billestrup N; Carter-Su C
    J Biol Chem; 1996 Jul; 271(30):18088-94. PubMed ID: 8663346
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential regulation by growth hormone (GH) of insulin-like growth factor I and GH receptor/binding protein gene expression in rat liver.
    Maiter D; Walker JL; Adam E; Moatsstaats B; Mulumba N; Ketelslegers JM; Underwood LE
    Endocrinology; 1992 Jun; 130(6):3257-64. PubMed ID: 1375898
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transgenic Wuzhishan minipigs designed to express a dominant-negative porcine growth hormone receptor display small stature and a perturbed insulin/IGF-1 pathway.
    Li F; Li Y; Liu H; Zhang X; Liu C; Tian K; Bolund L; Dou H; Yang W; Yang H; Staunstrup NH; Du Y
    Transgenic Res; 2015 Dec; 24(6):1029-42. PubMed ID: 26510874
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Growth hormone stimulates hepatic expression of bovine growth hormone receptor messenger ribonucleic acid through signal transducer and activator of transcription 5 activation of a major growth hormone receptor gene promoter.
    Jiang H; Wang Y; Wu M; Gu Z; Frank SJ; Torres-Diaz R
    Endocrinology; 2007 Jul; 148(7):3307-15. PubMed ID: 17412814
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tissue-specific regulation of growth hormone (GH) receptor and insulin-like growth factor-I gene expression in the pituitary and liver of GH-deficient (lit/lit) mice and transgenic mice that overexpress bovine GH (bGH) or a bGH antagonist.
    Iida K; Del Rincon JP; Kim DS; Itoh E; Nass R; Coschigano KT; Kopchick JJ; Thorner MO
    Endocrinology; 2004 Apr; 145(4):1564-70. PubMed ID: 14726438
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Liver-specific deletion of the growth hormone receptor reveals essential role of growth hormone signaling in hepatic lipid metabolism.
    Fan Y; Menon RK; Cohen P; Hwang D; Clemens T; DiGirolamo DJ; Kopchick JJ; Le Roith D; Trucco M; Sperling MA
    J Biol Chem; 2009 Jul; 284(30):19937-44. PubMed ID: 19460757
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ontogeny of GH receptor and GH-binding protein in the pig.
    Schnoebelen-Combes S; Louveau I; Postel-Vinay MC; Bonneau M
    J Endocrinol; 1996 Feb; 148(2):249-55. PubMed ID: 8699139
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ablation of Growth Hormone Receptor in GABAergic Neurons Leads to Increased Pulsatile Growth Hormone Secretion.
    Dos Santos WO; Wasinski F; Tavares MR; Campos AMP; Elias CF; List EO; Kopchick JJ; Szawka RE; Donato J
    Endocrinology; 2022 Aug; 163(8):. PubMed ID: 35803590
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.