BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

326 related articles for article (PubMed ID: 32281255)

  • 1. Genome-Wide Occupancy Profiling Reveals Critical Roles of FoxO1 in Regulating Extracellular Matrix and Circadian Rhythm Genes in Human Chondrocytes.
    Duffy T; Bekki H; Lotz MK
    Arthritis Rheumatol; 2020 Sep; 72(9):1514-1523. PubMed ID: 32281255
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Suppression of circadian clock protein cryptochrome 2 promotes osteoarthritis.
    Bekki H; Duffy T; Okubo N; Olmer M; Alvarez-Garcia O; Lamia K; Kay S; Lotz M
    Osteoarthritis Cartilage; 2020 Jul; 28(7):966-976. PubMed ID: 32339698
    [TBL] [Abstract][Full Text] [Related]  

  • 3. FoxO1 is a crucial mediator of TGF-β/TAK1 signaling and protects against osteoarthritis by maintaining articular cartilage homeostasis.
    Wang C; Shen J; Ying J; Xiao D; O'Keefe RJ
    Proc Natl Acad Sci U S A; 2020 Dec; 117(48):30488-30497. PubMed ID: 33199631
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The circadian clock in murine chondrocytes regulates genes controlling key aspects of cartilage homeostasis.
    Gossan N; Zeef L; Hensman J; Hughes A; Bateman JF; Rowley L; Little CB; Piggins HD; Rattray M; Boot-Handford RP; Meng QJ
    Arthritis Rheum; 2013 Sep; 65(9):2334-45. PubMed ID: 23896777
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dysregulated FOXO transcription factors in articular cartilage in aging and osteoarthritis.
    Akasaki Y; Hasegawa A; Saito M; Asahara H; Iwamoto Y; Lotz MK
    Osteoarthritis Cartilage; 2014 Jan; 22(1):162-70. PubMed ID: 24269635
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MEG3 promotes proliferation and inhibits apoptosis in osteoarthritis chondrocytes by miR-361-5p/FOXO1 axis.
    Wang A; Hu N; Zhang Y; Chen Y; Su C; Lv Y; Shen Y
    BMC Med Genomics; 2019 Dec; 12(1):201. PubMed ID: 31888661
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MicroRNA-92a-3p regulates the expression of cartilage-specific genes by directly targeting histone deacetylase 2 in chondrogenesis and degradation.
    Mao G; Zhang Z; Huang Z; Chen W; Huang G; Meng F; Zhang Z; Kang Y
    Osteoarthritis Cartilage; 2017 Apr; 25(4):521-532. PubMed ID: 27884646
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Knockdown of SGK1 alleviates the IL-1β-induced chondrocyte anabolic and catabolic imbalance by activating FoxO1-mediated autophagy in human chondrocytes.
    Huang W; Cheng C; Shan WS; Ding ZF; Liu FE; Lu W; He W; Xu JG; Yin ZS
    FEBS J; 2020 Jan; 287(1):94-107. PubMed ID: 31330080
    [TBL] [Abstract][Full Text] [Related]  

  • 9. LINC00623/miR-101/HRAS axis modulates IL-1β-mediated ECM degradation, apoptosis and senescence of osteoarthritis chondrocytes.
    Lü G; Li L; Wang B; Kuang L
    Aging (Albany NY); 2020 Feb; 12(4):3218-3237. PubMed ID: 32062610
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeted regulation of FoxO1 in chondrocytes prevents age-related osteoarthritis via autophagy mechanism.
    Yue J; Aobulikasimu A; Sun W; Liu S; Xie W; Sun W
    J Cell Mol Med; 2022 Jun; 26(11):3075-3082. PubMed ID: 35560791
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting Cartilage miR-195/497 Cluster for Osteoarthritis Treatment Regulates the Circadian Clock.
    Shi S; Zhang L; Wang Q; Wang Q; Li D; Sun W; Yi C
    Gerontology; 2024; 70(1):59-75. PubMed ID: 37827130
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Clock knockdown attenuated reactive oxygen species-mediated senescence of chondrocytes through restoring autophagic flux.
    Zhong J; Wang B; Wu B; Shang J; Jiang N; Cui A; Chen Y; Xu X; Lu H
    Life Sci; 2021 Mar; 269():119036. PubMed ID: 33450259
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dysregulated circadian rhythm pathway in human osteoarthritis: NR1D1 and BMAL1 suppression alters TGF-β signaling in chondrocytes.
    Akagi R; Akatsu Y; Fisch KM; Alvarez-Garcia O; Teramura T; Muramatsu Y; Saito M; Sasho T; Su AI; Lotz MK
    Osteoarthritis Cartilage; 2017 Jun; 25(6):943-951. PubMed ID: 27884645
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of BATF/JUN transcriptional activity protects against osteoarthritic cartilage destruction.
    Rhee J; Park SH; Kim SK; Kim JH; Ha CW; Chun CH; Chun JS
    Ann Rheum Dis; 2017 Feb; 76(2):427-434. PubMed ID: 27147707
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genome-wide analysis of FoxO1 binding in hepatic chromatin: potential involvement of FoxO1 in linking retinoid signaling to hepatic gluconeogenesis.
    Shin DJ; Joshi P; Hong SH; Mosure K; Shin DG; Osborne TF
    Nucleic Acids Res; 2012 Dec; 40(22):11499-509. PubMed ID: 23066095
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Resveratrol Improves the Progression of Osteoarthritis by Regulating the SIRT1-FoxO1 Pathway-Mediated Cholesterol Metabolism.
    Liang C; Xing H; Wang C; Xu X; Hao Y; Qiu B
    Mediators Inflamm; 2023; 2023():2936236. PubMed ID: 36643587
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Catabolic cytokines disrupt the circadian clock and the expression of clock-controlled genes in cartilage via an NFкB-dependent pathway.
    Guo B; Yang N; Borysiewicz E; Dudek M; Williams JL; Li J; Maywood ES; Adamson A; Hastings MH; Bateman JF; White MR; Boot-Handford RP; Meng QJ
    Osteoarthritis Cartilage; 2015 Nov; 23(11):1981-8. PubMed ID: 26521744
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Long Non-Coding RNA (lncRNA) Small Nucleolar RNA Host Gene 15 (SNHG15) Alleviates Osteoarthritis Progression by Regulation of Extracellular Matrix Homeostasis.
    Chen Y; Guo H; Li L; Bao D; Gao F; Li Q; Huang Q; Duan X; Xiang Z
    Med Sci Monit; 2020 Jul; 26():e923868. PubMed ID: 32643707
    [TBL] [Abstract][Full Text] [Related]  

  • 19. circPhc3 sponging microRNA‑93‑3p is involved in the regulation of chondrocyte function by mechanical instability in osteoarthritis.
    Wang Z; Rao Z; Wang X; Jiang C; Yang Y
    Int J Mol Med; 2022 Jan; 49(1):. PubMed ID: 34779488
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Intra-articular injection of microRNA-140 (miRNA-140) alleviates osteoarthritis (OA) progression by modulating extracellular matrix (ECM) homeostasis in rats.
    Si HB; Zeng Y; Liu SY; Zhou ZK; Chen YN; Cheng JQ; Lu YR; Shen B
    Osteoarthritis Cartilage; 2017 Oct; 25(10):1698-1707. PubMed ID: 28647469
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.