BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

150 related articles for article (PubMed ID: 32283344)

  • 1. Discovery and optimization of novel phenyldiazepine and pyridodiazepine based Aurora kinase inhibitors.
    Tamizharasan N; Gajendran C; Kristam R; Sulochana SP; Sivanandhan D; Mullangi R; Mathivathanan L; Hallur G; Suresh P
    Bioorg Chem; 2020 Jun; 99():103800. PubMed ID: 32283344
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Indolin-2-one derivatives as selective Aurora B kinase inhibitors targeting breast cancer.
    Dokla EME; Abdel-Aziz AK; Milik SN; Mahmoud AH; Saadeldin MK; McPhillie MJ; Minucci S; Abouzid KAM
    Bioorg Chem; 2021 Dec; 117():105451. PubMed ID: 34736137
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A thienopyrimidine derivative induces growth inhibition and apoptosis in human cancer cell lines via inhibiting Aurora B kinase activity.
    Li J; Hu H; Lang Q; Zhang H; Huang Q; Wu Y; Yu L
    Eur J Med Chem; 2013 Jul; 65():151-7. PubMed ID: 23707920
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of (7-aryl-1,5-naphthyridin-2-yl)ureas as dual inhibitors of ERK2 and Aurora B kinases with antiproliferative activity against cancer cells.
    Defaux J; Antoine M; Logé C; Le Borgne M; Schuster T; Seipelt I; Aicher B; Teifel M; Günther E; Gerlach M; Marchand P
    Bioorg Med Chem Lett; 2014 Aug; 24(16):3748-52. PubMed ID: 25022204
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, biological evaluation and molecular modeling study of 2-amino-3,5-disubstituted-pyrazines as Aurora kinases inhibitors.
    Bo YX; Xiang R; Xu Y; Hao SY; Wang XR; Chen SW
    Bioorg Med Chem; 2020 Mar; 28(5):115351. PubMed ID: 32035750
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design and synthesis of novel benzoxazole analogs as Aurora B kinase inhibitors.
    An Y; Lee E; Yu Y; Yun J; Lee MY; Kang JS; Kim WY; Jeon R
    Bioorg Med Chem Lett; 2016 Jul; 26(13):3067-3072. PubMed ID: 27209235
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Optimization and biological evaluation of nicotinamide derivatives as Aurora kinase inhibitors.
    Qi B; Xu X; Yang Y; He H; Yue X
    Bioorg Med Chem; 2019 Sep; 27(17):3825-3835. PubMed ID: 31307762
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pyrazolo[4,3-b]pyrimido[4,5-e][1,4]diazepine derivatives as new multi-targeted inhibitors of Aurora A/B and KDR.
    Zhang Q; Shen Q; Gao L; Tong L; Li J; Chen Y; Lu W
    Eur J Med Chem; 2018 Oct; 158():428-441. PubMed ID: 30241010
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-Based Discovery and Bioactivity Evaluation of Novel Aurora-A Kinase Inhibitors as Anticancer Agents via Docking-Based Comparative Intermolecular Contacts Analysis (dbCICA).
    Hijjawi MS; Abutayeh RF; Taha MO
    Molecules; 2020 Dec; 25(24):. PubMed ID: 33353031
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The synthesis and anti-tumour properties of novel 4-substituted phthalazinones as Aurora B kinase inhibitors.
    Zhang XJ; Xu Y; Mou HX; Wang S; Hao SY; Chen SW
    Bioorg Med Chem Lett; 2020 Dec; 30(23):127556. PubMed ID: 32941989
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A dual aurora and lim kinase inhibitor reduces glioblastoma proliferation and invasion.
    Rybin MJ; Laverde-Paz MJ; Suter RK; Affer M; Ayad NG; Feng Y; Zeier Z
    Bioorg Med Chem Lett; 2022 Apr; 61():128614. PubMed ID: 35151865
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Optimization and biological evaluation of 2-aminobenzothiazole derivatives as Aurora B kinase inhibitors.
    Lee E; An Y; Kwon J; Kim KI; Jeon R
    Bioorg Med Chem; 2017 Jul; 25(14):3614-3622. PubMed ID: 28529042
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Facile identification of dual FLT3-Aurora A inhibitors: a computer-guided drug design approach.
    Chang Hsu Y; Ke YY; Shiao HY; Lee CC; Lin WH; Chen CH; Yen KJ; Hsu JT; Chang C; Hsieh HP
    ChemMedChem; 2014 May; 9(5):953-61. PubMed ID: 24665000
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis, biological activity evaluation of 3-(4-phenyl-1H-imidazol-2-yl)-1H-pyrazole derivatives as potent JAK 2/3 and aurora A/B kinases multi-targeted inhibitors.
    Zheng YG; Wang JA; Meng L; Pei X; Zhang L; An L; Li CL; Miao YL
    Eur J Med Chem; 2021 Jan; 209():112934. PubMed ID: 33109396
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sulfonamide-based 4-anilinoquinoline derivatives as novel dual Aurora kinase (AURKA/B) inhibitors: Synthesis, biological evaluation and in silico insights.
    Al-Sanea MM; Elkamhawy A; Paik S; Lee K; El Kerdawy AM; Syed Nasir Abbas B; Joo Roh E; Eldehna WM; Elshemy HAH; Bakr RB; Ali Farahat I; Alzarea AI; Alzarea SI; Alharbi KS; Abdelgawad MA
    Bioorg Med Chem; 2020 Jul; 28(13):115525. PubMed ID: 32371117
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and bioevaluation of N-trisubstituted pyrimidine derivatives as potent aurora A kinase inhibitors.
    Luo Y; Deng YQ; Wang J; Long ZJ; Tu ZC; Peng W; Zhang JQ; Liu Q; Lu G
    Eur J Med Chem; 2014 May; 78():65-71. PubMed ID: 24681066
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of a highly selective inhibitor of the Aurora kinases.
    Ferguson FM; Doctor ZM; Chaikuad A; Sim T; Kim ND; Knapp S; Gray NS
    Bioorg Med Chem Lett; 2017 Sep; 27(18):4405-4408. PubMed ID: 28818446
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of novel 2,4-disubstituted pyrimidines as Aurora kinase inhibitors.
    Xu Y; Hao SY; Zhang XJ; Li WB; Qiao XP; Wang ZX; Chen SW
    Bioorg Med Chem Lett; 2020 Feb; 30(3):126885. PubMed ID: 31862411
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Click approach to the discovery of 1,2,3-triazolylsalicylamides as potent Aurora kinase inhibitors.
    Song D; Park Y; Yoon J; Aman W; Hah JM; Ryu JS
    Bioorg Med Chem; 2014 Sep; 22(17):4855-66. PubMed ID: 25042560
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and biological evaluation of novel 6,11-dihydro-5H-benzo[e]pyrimido- [5,4-b][1,4]diazepine derivatives as potential c-Met inhibitors.
    Huang D; Huang L; Zhang Q; Li J
    Eur J Med Chem; 2017 Nov; 140():212-228. PubMed ID: 28938137
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.