BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

453 related articles for article (PubMed ID: 32283346)

  • 1. Design, synthesis and biological evaluation of novel 2,4-bismorpholinothieno[3,2-d]pyrimidine and 2-morpholinothieno[3,2-d]pyrimidinone derivatives as potent antitumor agents.
    Ye T; Han Y; Wang R; Yan P; Chen S; Hou Y; Zhao Y
    Bioorg Chem; 2020 Jun; 99():103796. PubMed ID: 32283346
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, biological evaluation and molecular docking study of novel thieno[3,2-d]pyrimidine derivatives as potent FAK inhibitors.
    Wang R; Yu S; Zhao X; Chen Y; Yang B; Wu T; Hao C; Zhao D; Cheng M
    Eur J Med Chem; 2020 Feb; 188():112024. PubMed ID: 31923858
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New thieno[3,2-d]pyrimidine-based derivatives: Design, synthesis and biological evaluation as antiproliferative agents, EGFR and ARO inhibitors inducing apoptosis in breast cancer cells.
    Farghaly AM; AboulWafa OM; Baghdadi HH; Abd El Razik HA; Sedra SMY; Shamaa MM
    Bioorg Chem; 2021 Oct; 115():105208. PubMed ID: 34365057
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, anticancer activity and effects on cell cycle profile and apoptosis of novel thieno[2,3-d]pyrimidine and thieno[3,2-e] triazolo[4,3-c]pyrimidine derivatives.
    Kandeel MM; Refaat HM; Kassab AE; Shahin IG; Abdelghany TM
    Eur J Med Chem; 2015 Jan; 90():620-32. PubMed ID: 25499930
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis and biological evaluation of thieno[3,2-d]pyrimidine derivatives containing aroyl hydrazone or aryl hydrazide moieties for PI3K and mTOR dual inhibition.
    Han Y; Tian Y; Wang R; Fu S; Jiang J; Dong J; Qin M; Hou Y; Zhao Y
    Bioorg Chem; 2020 Nov; 104():104197. PubMed ID: 32927132
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and biological evaluation of novel thieno[3,2-d]pyrimidine derivatives containing diaryl urea moiety as potent antitumor agents.
    Liu Z; Wang Y; Lin H; Zuo D; Wang L; Zhao Y; Gong P
    Eur J Med Chem; 2014 Oct; 85():215-27. PubMed ID: 25086238
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and in vitro biological evaluation of novel [1,2,3]triazolo[4,5-d]pyrimidine derivatives containing a thiosemicarbazide moiety.
    Geng PF; Liu XQ; Zhao TQ; Wang CC; Li ZH; Zhang J; Wei HM; Hu B; Ma LY; Liu HM
    Eur J Med Chem; 2018 Feb; 146():147-156. PubMed ID: 29407946
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thieno[2,3-d]pyrimidin-4(3H)-one Derivatives of Benzimidazole as Potential Anti- Breast Cancer (MDA-MB-231, MCF-7) Agents.
    Dimov S; Mavrova AT; Yancheva D; Nikolova B; Tsoneva I
    Anticancer Agents Med Chem; 2021; 21(11):1441-1450. PubMed ID: 32698751
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel Pyrazolo[3,4-d]pyrimidines as Potential Cytotoxic Agents: Design, Synthesis, Molecular Docking and CDK2 Inhibition.
    Maher M; Kassab AE; Zaher AF; Mahmoud Z
    Anticancer Agents Med Chem; 2019; 19(11):1368-1381. PubMed ID: 31038080
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis and antitumor evaluation of novel 5-methylpyrazolo[1,5-a]pyrimidine derivatives as potential c-Met inhibitors.
    Luo G; Ma Y; Liang X; Xie G; Luo Y; Zha D; Wang S; Yu L; Zheng X; Wu W; Zhang C
    Bioorg Chem; 2020 Nov; 104():104356. PubMed ID: 33142417
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis and anticancer evaluation of thieno[2,3-d]pyrimidine derivatives as dual EGFR/HER2 inhibitors and apoptosis inducers.
    Elmetwally SA; Saied KF; Eissa IH; Elkaeed EB
    Bioorg Chem; 2019 Jul; 88():102944. PubMed ID: 31051400
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis and biological evaluation of novel thieno[3,2-d]pyrimidine and quinazoline derivatives as potent antitumor agents.
    Hu H; Dong Y; Li M; Wang R; Zhang X; Gong P; Zhao Y
    Bioorg Chem; 2019 Sep; 90():103086. PubMed ID: 31280016
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis and antiproliferative activity of novel 5-nitropyrimidine-2,4-diamine derivatives bearing alkyl acetate moiety.
    Zhao PL; Li YH; Yang HK; Chen P; Zhang B; Sun Q; Li Q; You WW
    Eur J Med Chem; 2016 Aug; 118():161-9. PubMed ID: 27128180
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, Synthesis and Anti-Proliferative Activities of 2,6-Substituted Thieno[3,2-d]pyrimidine Derivatives Containing Electrophilic Warheads.
    Zhang Q; Hu Z; Shen Q; Chen Y; Lu W
    Molecules; 2017 May; 22(5):. PubMed ID: 28498316
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis and biological evaluation of novel thieno[3,2-d]pyrimidine derivatives possessing diaryl semicarbazone scaffolds as potent antitumor agents.
    Liu Z; Wu S; Wang Y; Li R; Wang J; Wang L; Zhao Y; Gong P
    Eur J Med Chem; 2014 Nov; 87():782-93. PubMed ID: 25440879
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design and synthesis of novel 1,2,3-triazole-pyrimidine hybrids as potential anticancer agents.
    Ma LY; Pang LP; Wang B; Zhang M; Hu B; Xue DQ; Shao KP; Zhang BL; Liu Y; Zhang E; Liu HM
    Eur J Med Chem; 2014 Oct; 86():368-80. PubMed ID: 25180925
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis and biological evaluation of novel 7-amino-[1,2,4]triazolo[4,3-f]pteridinone, and 7-aminotetrazolo[1,5-f]pteridinone derivative as potent antitumor agents.
    Hou Y; Zhu L; Li Z; Shen Q; Xu Q; Li W; Liu Y; Gong P
    Eur J Med Chem; 2019 Feb; 163():690-709. PubMed ID: 30572179
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 6-Cinnamoyl-4-arylaminothienopyrimidines as highly potent cytotoxic agents: Design, synthesis and structure-activity relationship studies.
    Toolabi M; Moghimi S; Bakhshaiesh TO; Salarinejad S; Aghcheli A; Hasanvand Z; Nazeri E; Khalaj A; Esmaeili R; Foroumadi A
    Eur J Med Chem; 2020 Jan; 185():111786. PubMed ID: 31671308
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological evaluation of novel indole-pyrimidine hybrids bearing morpholine and thiomorpholine moieties.
    Diao PC; Li Q; Hu MJ; Ma YF; You WW; Hong KH; Zhao PL
    Eur J Med Chem; 2017 Jul; 134():110-118. PubMed ID: 28410492
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and biological evaluation of novel 7H-pyrrolo[2,3-d]pyrimidine derivatives as potential FAK inhibitors and anticancer agents.
    Wang R; Chen Y; Zhao X; Yu S; Yang B; Wu T; Guo J; Hao C; Zhao D; Cheng M
    Eur J Med Chem; 2019 Dec; 183():111716. PubMed ID: 31550660
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.