BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

161 related articles for article (PubMed ID: 32297218)

  • 21. Inhibiting Heat Shock Factor 1 in Cancer: A Unique Therapeutic Opportunity.
    Dong B; Jaeger AM; Thiele DJ
    Trends Pharmacol Sci; 2019 Dec; 40(12):986-1005. PubMed ID: 31727393
    [TBL] [Abstract][Full Text] [Related]  

  • 22. 1,4-Naphthoquinone activates the HSP90/HSF1 pathway through the S-arylation of HSP90 in A431 cells: Negative regulation of the redox signal transduction pathway by persulfides/polysulfides.
    Abiko Y; Sha L; Shinkai Y; Unoki T; Luong NC; Tsuchiya Y; Watanabe Y; Hirose R; Akaike T; Kumagai Y
    Free Radic Biol Med; 2017 Mar; 104():118-128. PubMed ID: 28049024
    [TBL] [Abstract][Full Text] [Related]  

  • 23. A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells.
    Massey AJ; Williamson DS; Browne H; Murray JB; Dokurno P; Shaw T; Macias AT; Daniels Z; Geoffroy S; Dopson M; Lavan P; Matassova N; Francis GL; Graham CJ; Parsons R; Wang Y; Padfield A; Comer M; Drysdale MJ; Wood M
    Cancer Chemother Pharmacol; 2010 Aug; 66(3):535-45. PubMed ID: 20012863
    [TBL] [Abstract][Full Text] [Related]  

  • 24. KRIBB11 inhibits HSP70 synthesis through inhibition of heat shock factor 1 function by impairing the recruitment of positive transcription elongation factor b to the hsp70 promoter.
    Yoon YJ; Kim JA; Shin KD; Shin DS; Han YM; Lee YJ; Lee JS; Kwon BM; Han DC
    J Biol Chem; 2011 Jan; 286(3):1737-47. PubMed ID: 21078672
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Regulating the master regulator: Controlling heat shock factor 1 as a chemotherapy approach.
    McConnell JR; Buckton LK; McAlpine SR
    Bioorg Med Chem Lett; 2015 Sep; 25(17):3409-14. PubMed ID: 26164188
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Molecular chaperones as HSF1-specific transcriptional repressors.
    Shi Y; Mosser DD; Morimoto RI
    Genes Dev; 1998 Mar; 12(5):654-66. PubMed ID: 9499401
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The small-molecule kinase inhibitor D11 counteracts 17-AAG-mediated up-regulation of HSP70 in brain cancer cells.
    Schaefer S; Svenstrup TH; Guerra B
    PLoS One; 2017; 12(5):e0177706. PubMed ID: 28542269
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Synthetic Small Molecule Modulators of Hsp70 and Hsp40 Chaperones as Promising Anticancer Agents.
    Nitzsche B; Höpfner M; Biersack B
    Int J Mol Sci; 2023 Feb; 24(4):. PubMed ID: 36835501
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The long noncoding RNA
    Lellahi SM; Rosenlund IA; Hedberg A; Kiær LT; Mikkola I; Knutsen E; Perander M
    J Biol Chem; 2018 Dec; 293(49):18965-18976. PubMed ID: 30305397
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Heat shock factor 1 is a promising therapeutic target against adult T-cell leukemia.
    Ishikawa C; Mori N
    Med Oncol; 2023 May; 40(6):172. PubMed ID: 37165174
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Hsp90 inhibitor geldanamycin increases hsp70 mRNA stabilisation but fails to activate HSF1 in cells exposed to hydrostatic pressure.
    Elo MA; Kaarniranta K; Helminen HJ; Lammi MJ
    Biochim Biophys Acta; 2005 Mar; 1743(1-2):115-9. PubMed ID: 15777846
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Regulation of the Hsf1-dependent transcriptome via conserved bipartite contacts with Hsp70 promotes survival in yeast.
    Peffer S; Gonçalves D; Morano KA
    J Biol Chem; 2019 Aug; 294(32):12191-12202. PubMed ID: 31239354
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Combination of Anti-Cancer Drugs with Molecular Chaperone Inhibitors.
    Shevtsov M; Multhoff G; Mikhaylova E; Shibata A; Guzhova I; Margulis B
    Int J Mol Sci; 2019 Oct; 20(21):. PubMed ID: 31652993
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Defining the Essential Function of Yeast Hsf1 Reveals a Compact Transcriptional Program for Maintaining Eukaryotic Proteostasis.
    Solís EJ; Pandey JP; Zheng X; Jin DX; Gupta PB; Airoldi EM; Pincus D; Denic V
    Mol Cell; 2016 Jul; 63(1):60-71. PubMed ID: 27320198
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Inhibition of HSP70: a challenging anti-cancer strategy.
    Goloudina AR; Demidov ON; Garrido C
    Cancer Lett; 2012 Dec; 325(2):117-24. PubMed ID: 22750096
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Synergetic cytotoxic activity toward breast cancer cells enhanced by the combination of Antp-TPR hybrid peptide targeting Hsp90 and Hsp70-targeted peptide.
    Horibe T; Torisawa A; Kohno M; Kawakami K
    BMC Cancer; 2014 Aug; 14():615. PubMed ID: 25159299
    [TBL] [Abstract][Full Text] [Related]  

  • 37. A screen for enhancers of clearance identifies huntingtin as a heat shock protein 90 (Hsp90) client protein.
    Baldo B; Weiss A; Parker CN; Bibel M; Paganetti P; Kaupmann K
    J Biol Chem; 2012 Jan; 287(2):1406-14. PubMed ID: 22123826
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Cancer cell responses to Hsp70 inhibitor JG-98: Comparison with Hsp90 inhibitors and finding synergistic drug combinations.
    Yaglom JA; Wang Y; Li A; Li Z; Monti S; Alexandrov I; Lu X; Sherman MY
    Sci Rep; 2018 Feb; 8(1):3010. PubMed ID: 29445088
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Heat shock factor 1 (HSF1)-targeted anticancer therapeutics: overview of current preclinical progress.
    Kijima T; Prince T; Neckers L; Koga F; Fujii Y
    Expert Opin Ther Targets; 2019 May; 23(5):369-377. PubMed ID: 30931649
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The Hsp70-Hsp90 go-between Hop/Stip1/Sti1 is a proteostatic switch and may be a drug target in cancer and neurodegeneration.
    Bhattacharya K; Picard D
    Cell Mol Life Sci; 2021 Dec; 78(23):7257-7273. PubMed ID: 34677645
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.