BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 32297665)

  • 1. Functional characterization of the antiepileptic drug candidate, padsevonil, on GABA
    Niespodziany I; Ghisdal P; Mullier B; Wood M; Provins L; Kaminski RM; Wolff C
    Epilepsia; 2020 May; 61(5):914-923. PubMed ID: 32297665
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pharmacological Profile of the Novel Antiepileptic Drug Candidate Padsevonil: Interactions with Synaptic Vesicle 2 Proteins and the GABA
    Wood M; Daniels V; Provins L; Wolff C; Kaminski RM; Gillard M
    J Pharmacol Exp Ther; 2020 Jan; 372(1):1-10. PubMed ID: 31619465
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacological Profile of the Novel Antiepileptic Drug Candidate Padsevonil: Characterization in Rodent Seizure and Epilepsy Models.
    Leclercq K; Matagne A; Provins L; Klitgaard H; Kaminski RM
    J Pharmacol Exp Ther; 2020 Jan; 372(1):11-20. PubMed ID: 31619464
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The interaction of general anaesthetics with recombinant GABAA and glycine receptors expressed in Xenopus laevis oocytes: a comparative study.
    Pistis M; Belelli D; Peters JA; Lambert JJ
    Br J Pharmacol; 1997 Dec; 122(8):1707-19. PubMed ID: 9422818
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The antiepileptic drug AWD 131-138 stimulates different recombinant isoforms of the rat GABA(A) receptor through the benzodiazepine binding site.
    Sigel E; Baur R; Netzer R; Rundfeldt C
    Neurosci Lett; 1998 Apr; 245(2):85-8. PubMed ID: 9605491
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of GABAA receptor function in human temporal cortical neurons.
    Gibbs JW; Zhang YF; Kao CQ; Holloway KL; Oh KS; Coulter DA
    J Neurophysiol; 1996 Apr; 75(4):1458-71. PubMed ID: 8727390
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Probing the molecular basis for affinity/potency- and efficacy-based subtype-selectivity exhibited by benzodiazepine-site modulators at GABA
    Söderhielm PC; Balle T; Bak-Nyhus S; Zhang M; Hansen KM; Ahring PK; Jensen AA
    Biochem Pharmacol; 2018 Dec; 158():339-358. PubMed ID: 30121248
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Positive allosteric modulation of GABA
    Sharma R; Nakamura M; Neupane C; Jeon BH; Shin H; Melnick SM; Glenn KJ; Jang IS; Park JB
    Eur J Pharmacol; 2020 Jul; 879():173117. PubMed ID: 32325146
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The dual modulatory effects of efavirenz on GABA
    Huang R; Chen Z; Dolan S; Schetz JA; Dillon GH
    Neuropharmacology; 2017 Jul; 121():167-178. PubMed ID: 28456686
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 6,3'-Dinitroflavone is a low efficacy modulator of GABA(A) receptors.
    Furtmueller R; Furtmueller B; Ramerstorfer J; Paladini AC; Wasowski C; Marder M; Huck S; Sieghart W
    Eur J Pharmacol; 2008 Sep; 591(1-3):142-6. PubMed ID: 18639544
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Impact of epsilon and theta subunits on pharmacological properties of alpha3beta1 GABAA receptors expressed in Xenopus oocytes.
    Ranna M; Sinkkonen ST; Möykkynen T; Uusi-Oukari M; Korpi ER
    BMC Pharmacol; 2006 Jan; 6():1. PubMed ID: 16412217
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Indiplon is a high-affinity positive allosteric modulator with selectivity for alpha1 subunit-containing GABAA receptors.
    Petroski RE; Pomeroy JE; Das R; Bowman H; Yang W; Chen AP; Foster AC
    J Pharmacol Exp Ther; 2006 Apr; 317(1):369-77. PubMed ID: 16399882
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Functional characterization of the 1,5-benzodiazepine clobazam and its major active metabolite N-desmethylclobazam at human GABA(A) receptors expressed in Xenopus laevis oocytes.
    Hammer H; Ebert B; Jensen HS; Jensen AA
    PLoS One; 2015; 10(3):e0120239. PubMed ID: 25798598
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SL651498: an anxioselective compound with functional selectivity for alpha2- and alpha3-containing gamma-aminobutyric acid(A) (GABA(A)) receptors.
    Griebel G; Perrault G; Simiand J; Cohen C; Granger P; Decobert M; Françon D; Avenet P; Depoortere H; Tan S; Oblin A; Schoemaker H; Evanno Y; Sevrin M; George P; Scatton B
    J Pharmacol Exp Ther; 2001 Aug; 298(2):753-68. PubMed ID: 11454940
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of alpha subunit on allosteric modulation of ion channel function in stably expressed human recombinant gamma-aminobutyric acid(A) receptors determined using (36)Cl ion flux.
    Smith AJ; Alder L; Silk J; Adkins C; Fletcher AE; Scales T; Kerby J; Marshall G; Wafford KA; McKernan RM; Atack JR
    Mol Pharmacol; 2001 May; 59(5):1108-18. PubMed ID: 11306694
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Direct activation of GABAA receptors by loreclezole, an anticonvulsant drug with selectivity for the beta-subunit.
    Sanna E; Murgia A; Casula A; Usala M; Maciocco E; Tuligi G; Biggio G
    Neuropharmacology; 1996; 35(12):1753-60. PubMed ID: 9076754
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular and neurochemical evaluation of the effects of etizolam on GABAA receptors under normal and stress conditions.
    Sanna E; Pau D; Tuveri F; Massa F; Maciocco E; Acquas C; Floris C; Fontana SN; Maira G; Biggio G
    Arzneimittelforschung; 1999 Feb; 49(2):88-95. PubMed ID: 10083975
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The orthosteric GABAA receptor ligand Thio-4-PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors.
    Hoestgaard-Jensen K; O'Connor RM; Dalby NO; Simonsen C; Finger BC; Golubeva A; Hammer H; Bergmann ML; Kristiansen U; Krogsgaard-Larsen P; Bräuner-Osborne H; Ebert B; Frølund B; Cryan JF; Jensen AA
    Br J Pharmacol; 2013 Oct; 170(4):919-32. PubMed ID: 23957253
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Positive modulation of synaptic and extrasynaptic GABAA receptors by an antagonist of the high affinity benzodiazepine binding site.
    Middendorp SJ; Maldifassi MC; Baur R; Sigel E
    Neuropharmacology; 2015 Aug; 95():459-67. PubMed ID: 25963418
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Thymol, a constituent of thyme essential oil, is a positive allosteric modulator of human GABA(A) receptors and a homo-oligomeric GABA receptor from Drosophila melanogaster.
    Priestley CM; Williamson EM; Wafford KA; Sattelle DB
    Br J Pharmacol; 2003 Dec; 140(8):1363-72. PubMed ID: 14623762
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.