284 related articles for article (PubMed ID: 32298377)
1. Combining lipoic acid to methylene blue reduces the Warburg effect in CHO cells: From TCA cycle activation to enhancing monoclonal antibody production.
Montégut L; Martínez-Basilio PC; da Veiga Moreira J; Schwartz L; Jolicoeur M
PLoS One; 2020; 15(4):e0231770. PubMed ID: 32298377
[TBL] [Abstract][Full Text] [Related]
2. Overexpression of the mitochondrial pyruvate carrier reduces lactate production and increases recombinant protein productivity in CHO cells.
Bulté DB; Palomares LA; Parra CG; Martínez JA; Contreras MA; Noriega LG; Ramírez OT
Biotechnol Bioeng; 2020 Sep; 117(9):2633-2647. PubMed ID: 32436990
[TBL] [Abstract][Full Text] [Related]
3. Metabolic engineering of CHO cells for the development of a robust protein production platform.
Gupta SK; Srivastava SK; Sharma A; Nalage VHH; Salvi D; Kushwaha H; Chitnis NB; Shukla P
PLoS One; 2017; 12(8):e0181455. PubMed ID: 28763459
[TBL] [Abstract][Full Text] [Related]
4. Metabolic analysis of antibody producing CHO cells in fed-batch production.
Dean J; Reddy P
Biotechnol Bioeng; 2013 Jun; 110(6):1735-47. PubMed ID: 23296898
[TBL] [Abstract][Full Text] [Related]
5. Metabolic flux analysis of CHO cells at growth and non-growth phases using isotopic tracers and mass spectrometry.
Ahn WS; Antoniewicz MR
Metab Eng; 2011 Sep; 13(5):598-609. PubMed ID: 21821143
[TBL] [Abstract][Full Text] [Related]
6. The Warburg effect in tumor progression: mitochondrial oxidative metabolism as an anti-metastasis mechanism.
Lu J; Tan M; Cai Q
Cancer Lett; 2015 Jan; 356(2 Pt A):156-64. PubMed ID: 24732809
[TBL] [Abstract][Full Text] [Related]
7. Improving culture performance and antibody production in CHO cell culture processes by reducing the Warburg effect.
Buchsteiner M; Quek LE; Gray P; Nielsen LK
Biotechnol Bioeng; 2018 Sep; 115(9):2315-2327. PubMed ID: 29704441
[TBL] [Abstract][Full Text] [Related]
8. Metabolic control at the cytosol-mitochondria interface in different growth phases of CHO cells.
Wahrheit J; Niklas J; Heinzle E
Metab Eng; 2014 May; 23():9-21. PubMed ID: 24525334
[TBL] [Abstract][Full Text] [Related]
9. A single nutrient feed supports both chemically defined NS0 and CHO fed-batch processes: Improved productivity and lactate metabolism.
Ma N; Ellet J; Okediadi C; Hermes P; McCormick E; Casnocha S
Biotechnol Prog; 2009; 25(5):1353-63. PubMed ID: 19637321
[TBL] [Abstract][Full Text] [Related]
10. Titer of trastuzumab produced by a Chinese hamster ovary cell line is associated with tricarboxylic acid cycle activity rather than lactate metabolism.
Ishii Y; Imamoto Y; Yamamoto R; Tsukahara M; Wakamatsu K
J Biosci Bioeng; 2015 Apr; 119(4):478-85. PubMed ID: 25449760
[TBL] [Abstract][Full Text] [Related]
11. Decreasing lactate level and increasing antibody production in Chinese Hamster Ovary cells (CHO) by reducing the expression of lactate dehydrogenase and pyruvate dehydrogenase kinases.
Zhou M; Crawford Y; Ng D; Tung J; Pynn AF; Meier A; Yuk IH; Vijayasankaran N; Leach K; Joly J; Snedecor B; Shen A
J Biotechnol; 2011 Apr; 153(1-2):27-34. PubMed ID: 21392546
[TBL] [Abstract][Full Text] [Related]
12. Metabolic engineering of CHO cells to alter lactate metabolism during fed-batch cultures.
Toussaint C; Henry O; Durocher Y
J Biotechnol; 2016 Jan; 217():122-31. PubMed ID: 26603123
[TBL] [Abstract][Full Text] [Related]
13. Model-directed engineering of "difficult-to-express" monoclonal antibody production by Chinese hamster ovary cells.
Pybus LP; Dean G; West NR; Smith A; Daramola O; Field R; Wilkinson SJ; James DC
Biotechnol Bioeng; 2014 Feb; 111(2):372-85. PubMed ID: 24081924
[TBL] [Abstract][Full Text] [Related]
14. Identification of active elementary flux modes in mitochondria using selectively permeabilized CHO cells.
Nicolae A; Wahrheit J; Nonnenmacher Y; Weyler C; Heinzle E
Metab Eng; 2015 Nov; 32():95-105. PubMed ID: 26417715
[TBL] [Abstract][Full Text] [Related]
15. Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors.
Zhang W; Hu X; Zhou W; Tam KY
J Proteome Res; 2018 Sep; 17(9):3012-3021. PubMed ID: 30028142
[TBL] [Abstract][Full Text] [Related]
16. Multi-scale computational study of the Warburg effect, reverse Warburg effect and glutamine addiction in solid tumors.
Shan M; Dai D; Vudem A; Varner JD; Stroock AD
PLoS Comput Biol; 2018 Dec; 14(12):e1006584. PubMed ID: 30532226
[TBL] [Abstract][Full Text] [Related]
17. Warburg effect increases steady-state ROS condition in cancer cells through decreasing their antioxidant capacities (anticancer effects of 3-bromopyruvate through antagonizing Warburg effect).
El Sayed SM; Mahmoud AA; El Sawy SA; Abdelaal EA; Fouad AM; Yousif RS; Hashim MS; Hemdan SB; Kadry ZM; Abdelmoaty MA; Gabr AG; Omran FM; Nabo MM; Ahmed NS
Med Hypotheses; 2013 Nov; 81(5):866-70. PubMed ID: 24071366
[TBL] [Abstract][Full Text] [Related]
18. Methylene blue stimulates substrate-level phosphorylation catalysed by succinyl-CoA ligase in the citric acid cycle.
Komlódi T; Tretter L
Neuropharmacology; 2017 Sep; 123():287-298. PubMed ID: 28495375
[TBL] [Abstract][Full Text] [Related]
19. Exometabolome profiling reveals activation of the carnitine buffering pathway in fed-batch cultures of CHO cells co-fed with glucose and lactic acid.
Vappiani J; Eyster T; Orzechowski K; Ritz D; Patel P; Sévin D; Aon J
Biotechnol Prog; 2021 Nov; 37(6):e3198. PubMed ID: 34328709
[TBL] [Abstract][Full Text] [Related]
20. Preventing pyruvate kinase muscle expression in Chinese hamster ovary cells curbs lactogenic behavior by altering glycolysis, gating pyruvate generation, and increasing pyruvate flux into the TCA cycle.
Tang D; Sandoval W; Liu P; Lam C; Snedecor B; Misaghi S
Biotechnol Prog; 2021 Sep; 37(5):e3193. PubMed ID: 34288605
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
