These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 32304407)

  • 1. Growth inhibition and apoptosis of human multiple myeloma cells induced by 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid derivatives.
    Rogers LJ; John T; Park J; Tucker M; Ma H; Wu Y; Rayalam S; Wang X
    Anticancer Drugs; 2020 Sep; 31(8):806-818. PubMed ID: 32304407
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Induction of redox imbalance and apoptosis in multiple myeloma cells by the novel triterpenoid 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid.
    Ikeda T; Nakata Y; Kimura F; Sato K; Anderson K; Motoyoshi K; Sporn M; Kufe D
    Mol Cancer Ther; 2004 Jan; 3(1):39-45. PubMed ID: 14749474
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The bortezomib/proteasome inhibitor PS-341 and triterpenoid CDDO-Im induce synergistic anti-multiple myeloma (MM) activity and overcome bortezomib resistance.
    Chauhan D; Li G; Podar K; Hideshima T; Shringarpure R; Catley L; Mitsiades C; Munshi N; Tai YT; Suh N; Gribble GW; Honda T; Schlossman R; Richardson P; Sporn MB; Anderson KC
    Blood; 2004 Apr; 103(8):3158-66. PubMed ID: 15070698
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthetic triterpenoids inhibit growth and induce apoptosis in human glioblastoma and neuroblastoma cells through inhibition of prosurvival Akt, NF-kappaB and Notch1 signaling.
    Gao X; Deeb D; Jiang H; Liu Y; Dulchavsky SA; Gautam SC
    J Neurooncol; 2007 Sep; 84(2):147-57. PubMed ID: 17361329
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) directly targets mitochondrial glutathione to induce apoptosis in pancreatic cancer.
    Samudio I; Konopleva M; Hail N; Shi YX; McQueen T; Hsu T; Evans R; Honda T; Gribble GW; Sporn M; Gilbert HF; Safe S; Andreeff M
    J Biol Chem; 2005 Oct; 280(43):36273-82. PubMed ID: 16118208
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Apoptotic activity and mechanism of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic-acid and related synthetic triterpenoids in prostate cancer.
    Hyer ML; Shi R; Krajewska M; Meyer C; Lebedeva IV; Fisher PB; Reed JC
    Cancer Res; 2008 Apr; 68(8):2927-33. PubMed ID: 18413762
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CDDO-imidazolide induces DNA damage, G2/M arrest and apoptosis in BRCA1-mutated breast cancer cells.
    Kim EH; Deng CX; Sporn MB; Liby KT
    Cancer Prev Res (Phila); 2011 Mar; 4(3):425-34. PubMed ID: 21372041
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The novel synthetic triterpenoid, CDDO-imidazolide, inhibits inflammatory response and tumor growth in vivo.
    Place AE; Suh N; Williams CR; Risingsong R; Honda T; Honda Y; Gribble GW; Leesnitzer LM; Stimmel JB; Willson TM; Rosen E; Sporn MB
    Clin Cancer Res; 2003 Jul; 9(7):2798-806. PubMed ID: 12855660
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthetic triterpenoids cooperate with tumor necrosis factor-related apoptosis-inducing ligand to induce apoptosis of breast cancer cells.
    Hyer ML; Croxton R; Krajewska M; Krajewski S; Kress CL; Lu M; Suh N; Sporn MB; Cryns VL; Zapata JM; Reed JC
    Cancer Res; 2005 Jun; 65(11):4799-808. PubMed ID: 15930300
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CDDO-imidazolide mediated inhibition of malignant cell growth in Waldenström macroglobulinemia.
    Elsawa SF; Novak AJ; Grote D; Konopleva M; Andreeff M; Witzig TE; Ansell SM
    Leuk Res; 2008 Dec; 32(12):1895-902. PubMed ID: 18468679
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 2-Cyano-3,12-dioxoolean-1,9-dien-28-oic acid and related compounds inhibit growth of colon cancer cells through peroxisome proliferator-activated receptor gamma-dependent and -independent pathways.
    Chintharlapalli S; Papineni S; Konopleva M; Andreef M; Samudio I; Safe S
    Mol Pharmacol; 2005 Jul; 68(1):119-28. PubMed ID: 15798084
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel synthetic pyridyl analogues of CDDO-Imidazolide are useful new tools in cancer prevention.
    Cao M; Onyango EO; Williams CR; Royce DB; Gribble GW; Sporn MB; Liby KT
    Pharmacol Res; 2015 Oct; 100():135-47. PubMed ID: 26238177
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The synthetic triterpenoid CDDO-imidazolide induces monocytic differentiation by activating the Smad and ERK signaling pathways in HL60 leukemia cells.
    Ji Y; Lee HJ; Goodman C; Uskokovic M; Liby K; Sporn M; Suh N
    Mol Cancer Ther; 2006 Jun; 5(6):1452-8. PubMed ID: 16818503
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The synthetic triterpenoid CDDO-Im inhibits fatty acid synthase expression and has antiproliferative and proapoptotic effects in human liposarcoma cells.
    Hughes DT; Martel PM; Kinlaw WB; Eisenberg BL
    Cancer Invest; 2008 Mar; 26(2):118-27. PubMed ID: 18259941
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1-[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole.
    Yates MS; Kwak MK; Egner PA; Groopman JD; Bodreddigari S; Sutter TR; Baumgartner KJ; Roebuck BD; Liby KT; Yore MM; Honda T; Gribble GW; Sporn MB; Kensler TW
    Cancer Res; 2006 Feb; 66(4):2488-94. PubMed ID: 16489057
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CDDO-Imidazolide inhibits growth and survival of c-Myc-induced mouse B cell and plasma cell neoplasms.
    Han SS; Peng L; Chung ST; DuBois W; Maeng SH; Shaffer AL; Sporn MB; Janz S
    Mol Cancer; 2006 Jun; 5():22. PubMed ID: 16759389
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The novel triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) potently enhances apoptosis induced by tumor necrosis factor in human leukemia cells.
    Stadheim TA; Suh N; Ganju N; Sporn MB; Eastman A
    J Biol Chem; 2002 May; 277(19):16448-55. PubMed ID: 11880365
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthetic triterpenoids activate a pathway for apoptosis in AML cells involving downregulation of FLIP and sensitization to TRAIL.
    Suh WS; Kim YS; Schimmer AD; Kitada S; Minden M; Andreeff M; Suh N; Sporn M; Reed JC
    Leukemia; 2003 Nov; 17(11):2122-9. PubMed ID: 12931220
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling.
    Liby K; Hock T; Yore MM; Suh N; Place AE; Risingsong R; Williams CR; Royce DB; Honda T; Honda Y; Gribble GW; Hill-Kapturczak N; Agarwal A; Sporn MB
    Cancer Res; 2005 Jun; 65(11):4789-98. PubMed ID: 15930299
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Human neuroblastoma cells rapidly enter cell cycle arrest and apoptosis following exposure to C-28 derivatives of the synthetic triterpenoid CDDO.
    Alabran JL; Cheuk A; Liby K; Sporn M; Khan J; Letterio J; Leskov KS
    Cancer Biol Ther; 2008 May; 7(5):709-17. PubMed ID: 18277094
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.