BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 32307917)

  • 1. Inhibition of PIM1 attenuates the stem cell-like traits of breast cancer cells by promoting RUNX3 nuclear retention.
    Liu H; Chen C; Ma D; Li Y; Yin Q; Li Q; Xiang C
    J Cell Mol Med; 2020 Jun; 24(11):6308-6323. PubMed ID: 32307917
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PIM1 is responsible for IL-6-induced breast cancer cell EMT and stemness via c-myc activation.
    Gao X; Liu X; Lu Y; Wang Y; Cao W; Liu X; Hu H; Wang H
    Breast Cancer; 2019 Sep; 26(5):663-671. PubMed ID: 30989585
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of Pim1 kinase prevents peanut allergy by enhancing Runx3 expression and suppressing T(H)2 and T(H)17 T-cell differentiation.
    Wang M; Okamoto M; Domenico J; Han J; Ashino S; Shin YS; Gelfand EW
    J Allergy Clin Immunol; 2012 Oct; 130(4):932-44.e12. PubMed ID: 22944483
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis.
    Zhao B; Liu L; Mao J; Zhang Z; Wang Q; Li Q
    Cell Death Dis; 2018 Feb; 9(3):307. PubMed ID: 29472550
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Src kinase phosphorylates RUNX3 at tyrosine residues and localizes the protein in the cytoplasm.
    Goh YM; Cinghu S; Hong ETH; Lee YS; Kim JH; Jang JW; Li YH; Chi XZ; Lee KS; Wee H; Ito Y; Oh BC; Bae SC
    J Biol Chem; 2010 Mar; 285(13):10122-10129. PubMed ID: 20100835
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Runx3 protects gastric epithelial cells against epithelial-mesenchymal transition-induced cellular plasticity and tumorigenicity.
    Voon DC; Wang H; Koo JK; Nguyen TA; Hor YT; Chu YS; Ito K; Fukamachi H; Chan SL; Thiery JP; Ito Y
    Stem Cells; 2012 Oct; 30(10):2088-99. PubMed ID: 22899304
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Restored expression of the tumor suppressor gene RUNX3 reduces cancer stem cells in hepatocellular carcinoma by suppressing Jagged1-Notch signaling.
    Nishina S; Shiraha H; Nakanishi Y; Tanaka S; Matsubara M; Takaoka N; Uemura M; Horiguchi S; Kataoka J; Iwamuro M; Yagi T; Yamamoto K
    Oncol Rep; 2011 Sep; 26(3):523-31. PubMed ID: 21637926
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Expression of RUNX3 gene, methylation status and clinicopathological significance in breast cancer and breast cancer cell lines.
    Jiang Y; Tong D; Lou G; Zhang Y; Geng J
    Pathobiology; 2008; 75(4):244-51. PubMed ID: 18580070
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pim-1 kinase phosphorylates RUNX family transcription factors and enhances their activity.
    Aho TL; Sandholm J; Peltola KJ; Ito Y; Koskinen PJ
    BMC Cell Biol; 2006 May; 7():21. PubMed ID: 16684349
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells.
    Blanco FF; Jimbo M; Wulfkuhle J; Gallagher I; Deng J; Enyenihi L; Meisner-Kober N; Londin E; Rigoutsos I; Sawicki JA; Risbud MV; Witkiewicz AK; McCue PA; Jiang W; Rui H; Yeo CJ; Petricoin E; Winter JM; Brody JR
    Oncogene; 2016 May; 35(19):2529-41. PubMed ID: 26387536
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pim-1 kinase phosphorylates and stabilizes RUNX3 and alters its subcellular localization.
    Kim HR; Oh BC; Choi JK; Bae SC
    J Cell Biochem; 2008 Nov; 105(4):1048-58. PubMed ID: 18767071
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nalbuphine suppresses breast cancer stem-like properties and epithelial-mesenchymal transition via the AKT-NFκB signaling pathway.
    Yu J; Luo Y; Wen Q
    J Exp Clin Cancer Res; 2019 May; 38(1):197. PubMed ID: 31092275
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PIM1: a promising target in patients with triple-negative breast cancer.
    Zhao W; Qiu R; Li P; Yang J
    Med Oncol; 2017 Aug; 34(8):142. PubMed ID: 28721678
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PIM1-dependent phosphorylation of histone H3 at serine 10 is required for MYC-dependent transcriptional activation and oncogenic transformation.
    Zippo A; De Robertis A; Serafini R; Oliviero S
    Nat Cell Biol; 2007 Aug; 9(8):932-44. PubMed ID: 17643117
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of PIM1 substrates reveals a role for NDRG1 phosphorylation in prostate cancer cellular migration and invasion.
    Ledet RJ; Ruff SE; Wang Y; Nayak S; Schneider JA; Ueberheide B; Logan SK; Garabedian MJ
    Commun Biol; 2021 Jan; 4(1):36. PubMed ID: 33398037
    [TBL] [Abstract][Full Text] [Related]  

  • 16. By promoting cell differentiation, miR-100 sensitizes basal-like breast cancer stem cells to hormonal therapy.
    Petrelli A; Carollo R; Cargnelutti M; Iovino F; Callari M; Cimino D; Todaro M; Mangiapane LR; Giammona A; Cordova A; Montemurro F; Taverna D; Daidone MG; Stassi G; Giordano S
    Oncotarget; 2015 Feb; 6(4):2315-30. PubMed ID: 25537513
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels.
    Morishita D; Katayama R; Sekimizu K; Tsuruo T; Fujita N
    Cancer Res; 2008 Jul; 68(13):5076-85. PubMed ID: 18593906
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PIM kinases are essential for chronic lymphocytic leukemia cell survival (PIM2/3) and CXCR4-mediated microenvironmental interactions (PIM1).
    Decker S; Finter J; Forde AJ; Kissel S; Schwaller J; Mack TS; Kuhn A; Gray N; Follo M; Jumaa H; Burger M; Zirlik K; Pfeifer D; Miduturu CV; Eibel H; Veelken H; Dierks C
    Mol Cancer Ther; 2014 May; 13(5):1231-45. PubMed ID: 24659821
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PIM1 regulates glycolysis and promotes tumor progression in hepatocellular carcinoma.
    Leung CO; Wong CC; Fan DN; Kai AK; Tung EK; Xu IM; Ng IO; Lo RC
    Oncotarget; 2015 May; 6(13):10880-92. PubMed ID: 25834102
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tumor suppressor, AT motif binding factor 1 (ATBF1), translocates to the nucleus with runt domain transcription factor 3 (RUNX3) in response to TGF-beta signal transduction.
    Mabuchi M; Kataoka H; Miura Y; Kim TS; Kawaguchi M; Ebi M; Tanaka M; Mori Y; Kubota E; Mizushima T; Shimura T; Mizoshita T; Tanida S; Kamiya T; Asai K; Joh T
    Biochem Biophys Res Commun; 2010 Jul; 398(2):321-5. PubMed ID: 20599712
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.