These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

368 related articles for article (PubMed ID: 32317284)

  • 1. The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
    Holt C; Hamborg L; Lau K; Brohus M; Sørensen AB; Larsen KT; Sommer C; Van Petegem F; Overgaard MT; Wimmer R
    J Biol Chem; 2020 May; 295(22):7620-7634. PubMed ID: 32317284
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Arrhythmogenic Calmodulin Mutations Affect the Activation and Termination of Cardiac Ryanodine Receptor-mediated Ca2+ Release.
    Søndergaard MT; Tian X; Liu Y; Wang R; Chazin WJ; Chen SR; Overgaard MT
    J Biol Chem; 2015 Oct; 290(43):26151-62. PubMed ID: 26309258
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of cardiac ryanodine receptor calmodulin-binding domains in mediating the action of arrhythmogenic calmodulin N-domain mutation N54I.
    Søndergaard MT; Liu Y; Guo W; Wei J; Wang R; Brohus M; Overgaard MT; Chen SRW
    FEBS J; 2020 Jun; 287(11):2256-2280. PubMed ID: 31763755
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Divergent regulation of ryanodine receptor 2 calcium release channels by arrhythmogenic human calmodulin missense mutants.
    Hwang HS; Nitu FR; Yang Y; Walweel K; Pereira L; Johnson CN; Faggioni M; Chazin WJ; Laver D; George AL; Cornea RL; Bers DM; Knollmann BC
    Circ Res; 2014 Mar; 114(7):1114-24. PubMed ID: 24563457
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+ Binding but Not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor.
    Søndergaard MT; Liu Y; Larsen KT; Nani A; Tian X; Holt C; Wang R; Wimmer R; Van Petegem F; Fill M; Chen SR; Overgaard MT
    J Biol Chem; 2017 Jan; 292(4):1385-1395. PubMed ID: 27927985
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ca
    Brohus M; Søndergaard MT; Wayne Chen SR; van Petegem F; Overgaard MT
    Biochem J; 2019 Jan; 476(2):193-209. PubMed ID: 30530841
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel Calmodulin Variant p.E46K Associated With Severe Catecholaminergic Polymorphic Ventricular Tachycardia Produces Robust Arrhythmogenicity in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
    Gao J; Makiyama T; Yamamoto Y; Kobayashi T; Aoki H; Maurissen TL; Wuriyanghai Y; Kashiwa A; Imamura T; Aizawa T; Huang H; Kohjitani H; Nishikawa M; Chonabayashi K; Fukuyama M; Manabe H; Nakau K; Wada T; Kato K; Toyoda F; Yoshida Y; Makita N; Woltjen K; Ohno S; Kurebayashi N; Murayama T; Sakurai T; Horie M; Kimura T
    Circ Arrhythm Electrophysiol; 2023 Mar; 16(3):e011387. PubMed ID: 36866681
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Site-specific modification of calmodulin Ca²(+) affinity tunes the skeletal muscle ryanodine receptor activation profile.
    Jiang J; Zhou Y; Zou J; Chen Y; Patel P; Yang JJ; Balog EM
    Biochem J; 2010 Nov; 432(1):89-99. PubMed ID: 20815817
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Calmodulin variant E140G associated with long QT syndrome impairs CaMKIIδ autophosphorylation and L-type calcium channel inactivation.
    Prakash O; Gupta N; Milburn A; McCormick L; Deugi V; Fisch P; Wyles J; Thomas NL; Antonyuk S; Dart C; Helassa N
    J Biol Chem; 2023 Jan; 299(1):102777. PubMed ID: 36496072
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Diminished inhibition and facilitated activation of RyR2-mediated Ca
    Søndergaard MT; Liu Y; Brohus M; Guo W; Nani A; Carvajal C; Fill M; Overgaard MT; Chen SRW
    FEBS J; 2019 Nov; 286(22):4554-4578. PubMed ID: 31230402
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CPVT-associated calmodulin variants N53I and A102V dysregulate Ca2+ signalling via different mechanisms.
    Prakash O; Held M; McCormick LF; Gupta N; Lian LY; Antonyuk S; Haynes LP; Thomas NL; Helassa N
    J Cell Sci; 2022 Jan; 135(2):. PubMed ID: 34888671
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Arrhythmogenic calmodulin E105A mutation alters cardiac RyR2 regulation leading to cardiac dysfunction in zebrafish.
    Da'as SI; Thanassoulas A; Calver BL; Beck K; Salem R; Saleh A; Kontogianni I; Al-Maraghi A; Nasrallah GK; Safieh-Garabedian B; Toft E; Nounesis G; Lai FA; Nomikos M
    Ann N Y Acad Sci; 2019 Jul; 1448(1):19-29. PubMed ID: 30937913
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ryanodine receptor-bound calmodulin is essential to protect against catecholaminergic polymorphic ventricular tachycardia.
    Nakamura Y; Yamamoto T; Kobayashi S; Tamitani M; Hamada Y; Fukui G; Xu X; Nishimura S; Kato T; Uchinoumi H; Oda T; Okuda S; Yano M
    JCI Insight; 2019 Jun; 4(11):. PubMed ID: 31167968
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function.
    Da'as SI; Thanassoulas A; Calver BL; Saleh A; Abdelrahman D; Hasan W; Safieh-Garabedian B; Kontogianni I; Nasrallah GK; Nounesis G; Lai FA; Nomikos M
    J Cell Biochem; 2024 Aug; 125(8):e30619. PubMed ID: 38946237
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Calmodulin mutations causing catecholaminergic polymorphic ventricular tachycardia confer opposing functional and biophysical molecular changes.
    Søndergaard MT; Sorensen AB; Skov LL; Kjaer-Sorensen K; Bauer MC; Nyegaard M; Linse S; Oxvig C; Overgaard MT
    FEBS J; 2015 Feb; 282(4):803-16. PubMed ID: 25557436
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Defective calmodulin binding to the cardiac ryanodine receptor plays a key role in CPVT-associated channel dysfunction.
    Xu X; Yano M; Uchinoumi H; Hino A; Suetomi T; Ono M; Tateishi H; Oda T; Okuda S; Doi M; Kobayashi S; Yamamoto T; Ikeda Y; Ikemoto N; Matsuzaki M
    Biochem Biophys Res Commun; 2010 Apr; 394(3):660-6. PubMed ID: 20226167
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Distinctive malfunctions of calmodulin mutations associated with heart RyR2-mediated arrhythmic disease.
    Vassilakopoulou V; Calver BL; Thanassoulas A; Beck K; Hu H; Buntwal L; Smith A; Theodoridou M; Kashir J; Blayney L; Livaniou E; Nounesis G; Lai FA; Nomikos M
    Biochim Biophys Acta; 2015 Nov; 1850(11):2168-76. PubMed ID: 26164367
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutation-linked, excessively tight interaction between the calmodulin binding domain and the C-terminal domain of the cardiac ryanodine receptor as a novel cause of catecholaminergic polymorphic ventricular tachycardia.
    Nishimura S; Yamamoto T; Nakamura Y; Kohno M; Hamada Y; Sufu Y; Fukui G; Nanno T; Ishiguchi H; Kato T; Xu X; Ono M; Oda T; Okuda S; Kobayashi S; Yano M
    Heart Rhythm; 2018 Jun; 15(6):905-914. PubMed ID: 29427818
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Gene Transfer of Engineered Calmodulin Alleviates Ventricular Arrhythmias in a Calsequestrin-Associated Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia.
    Liu B; Walton SD; Ho HT; Belevych AE; Tikunova SB; Bonilla I; Shettigar V; Knollmann BC; Priori SG; Volpe P; Radwański PB; Davis JP; Györke S
    J Am Heart Assoc; 2018 May; 7(10):. PubMed ID: 29720499
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Computational Analysis of Binding Interactions between the Ryanodine Receptor Type 2 and Calmodulin.
    Greene D; Barton M; Luchko T; Shiferaw Y
    J Phys Chem B; 2021 Sep; 125(38):10720-10735. PubMed ID: 34533024
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.