895 related articles for article (PubMed ID: 32330092)
1. Small molecule inhibition of gut microbial choline trimethylamine lyase activity alters host cholesterol and bile acid metabolism.
Pathak P; Helsley RN; Brown AL; Buffa JA; Choucair I; Nemet I; Gogonea CB; Gogonea V; Wang Z; Garcia-Garcia JC; Cai L; Temel R; Sangwan N; Hazen SL; Brown JM
Am J Physiol Heart Circ Physiol; 2020 Jun; 318(6):H1474-H1486. PubMed ID: 32330092
[TBL] [Abstract][Full Text] [Related]
2. Flavin monooxygenase 3, the host hepatic enzyme in the metaorganismal trimethylamine N-oxide-generating pathway, modulates platelet responsiveness and thrombosis risk.
Zhu W; Buffa JA; Wang Z; Warrier M; Schugar R; Shih DM; Gupta N; Gregory JC; Org E; Fu X; Li L; DiDonato JA; Lusis AJ; Brown JM; Hazen SL
J Thromb Haemost; 2018 Sep; 16(9):1857-1872. PubMed ID: 29981269
[TBL] [Abstract][Full Text] [Related]
3. Targeted Inhibition of Gut Microbial Trimethylamine N-Oxide Production Reduces Renal Tubulointerstitial Fibrosis and Functional Impairment in a Murine Model of Chronic Kidney Disease.
Gupta N; Buffa JA; Roberts AB; Sangwan N; Skye SM; Li L; Ho KJ; Varga J; DiDonato JA; Tang WHW; Hazen SL
Arterioscler Thromb Vasc Biol; 2020 May; 40(5):1239-1255. PubMed ID: 32212854
[TBL] [Abstract][Full Text] [Related]
4. Trigonelline inhibits intestinal microbial metabolism of choline and its associated cardiovascular risk.
Anwar S; Bhandari U; Panda BP; Dubey K; Khan W; Ahmad S
J Pharm Biomed Anal; 2018 Sep; 159():100-112. PubMed ID: 29980011
[TBL] [Abstract][Full Text] [Related]
5. Resveratrol Attenuates Trimethylamine-N-Oxide (TMAO)-Induced Atherosclerosis by Regulating TMAO Synthesis and Bile Acid Metabolism via Remodeling of the Gut Microbiota.
Chen ML; Yi L; Zhang Y; Zhou X; Ran L; Yang J; Zhu JD; Zhang QY; Mi MT
mBio; 2016 Apr; 7(2):e02210-15. PubMed ID: 27048804
[TBL] [Abstract][Full Text] [Related]
6. Intestinal microbiota composition modulates choline bioavailability from diet and accumulation of the proatherogenic metabolite trimethylamine-N-oxide.
Romano KA; Vivas EI; Amador-Noguez D; Rey FE
mBio; 2015 Mar; 6(2):e02481. PubMed ID: 25784704
[TBL] [Abstract][Full Text] [Related]
7. Nonlethal Inhibition of Gut Microbial Trimethylamine N-oxide Production Improves Cardiac Function and Remodeling in a Murine Model of Heart Failure.
Organ CL; Li Z; Sharp TE; Polhemus DJ; Gupta N; Goodchild TT; Tang WHW; Hazen SL; Lefer DJ
J Am Heart Assoc; 2020 May; 9(10):e016223. PubMed ID: 32390485
[TBL] [Abstract][Full Text] [Related]
8. Dietary phenolics and their microbial metabolites are poor inhibitors of trimethylamine oxidation to trimethylamine N-oxide by hepatic flavin monooxygenase 3.
Iglesias-Carres L; Chadwick-Corbin SA; Sweet MG; Neilson AP
J Nutr Biochem; 2023 Oct; 120():109428. PubMed ID: 37549832
[TBL] [Abstract][Full Text] [Related]
9. Trimethylamine
Canyelles M; Tondo M; Cedó L; Farràs M; Escolà-Gil JC; Blanco-Vaca F
Int J Mol Sci; 2018 Oct; 19(10):. PubMed ID: 30347638
[TBL] [Abstract][Full Text] [Related]
10. Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms.
Schugar RC; Gliniak CM; Osborn LJ; Massey W; Sangwan N; Horak A; Banerjee R; Orabi D; Helsley RN; Brown AL; Burrows A; Finney C; Fung KK; Allen FM; Ferguson D; Gromovsky AD; Neumann C; Cook K; McMillan A; Buffa JA; Anderson JT; Mehrabian M; Goudarzi M; Willard B; Mak TD; Armstrong AR; Swanson G; Keshavarzian A; Garcia-Garcia JC; Wang Z; Lusis AJ; Hazen SL; Brown JM
Elife; 2022 Jan; 11():. PubMed ID: 35072627
[TBL] [Abstract][Full Text] [Related]
11. Dietary Methionine Restriction Alleviates Choline-Induced Tri-Methylamine-N-Oxide (TMAO) Elevation by Manipulating Gut Microbiota in Mice.
Lu M; Yang Y; Xu Y; Wang X; Li B; Le G; Xie Y
Nutrients; 2023 Jan; 15(1):. PubMed ID: 36615863
[TBL] [Abstract][Full Text] [Related]
12. Blueberry intervention mitigates detrimental microbial metabolite trimethylamine N-oxide by modulating gut microbes.
Satheesh Babu AK; Petersen C; Iglesias-Carres L; Paz HA; Wankhade UD; Neilson AP; Anandh Babu PV
Biofactors; 2024; 50(2):392-404. PubMed ID: 37921575
[TBL] [Abstract][Full Text] [Related]
13. Gut microbial trimethylamine is elevated in alcohol-associated hepatitis and contributes to ethanol-induced liver injury in mice.
Helsley RN; Miyata T; Kadam A; Varadharajan V; Sangwan N; Huang EC; Banerjee R; Brown AL; Fung KK; Massey WJ; Neumann C; Orabi D; Osborn LJ; Schugar RC; McMullen MR; Bellar A; Poulsen KL; Kim A; Pathak V; Mrdjen M; Anderson JT; Willard B; McClain CJ; Mitchell M; McCullough AJ; Radaeva S; Barton B; Szabo G; Dasarathy S; Garcia-Garcia JC; Rotroff DM; Allende DS; Wang Z; Hazen SL; Nagy LE; Brown JM
Elife; 2022 Jan; 11():. PubMed ID: 35084335
[TBL] [Abstract][Full Text] [Related]
14. Gut Microbiota-Derived Trimethylamine N-Oxide Contributes to Abdominal Aortic Aneurysm Through Inflammatory and Apoptotic Mechanisms.
Benson TW; Conrad KA; Li XS; Wang Z; Helsley RN; Schugar RC; Coughlin TM; Wadding-Lee C; Fleifil S; Russell HM; Stone T; Brooks M; Buffa JA; Mani K; Björck M; Wanhainen A; Sangwan N; Biddinger S; Bhandari R; Ademoya A; Pascual C; Tang WHW; Tranter M; Cameron SJ; Brown JM; Hazen SL; Owens AP
Circulation; 2023 Apr; 147(14):1079-1096. PubMed ID: 37011073
[TBL] [Abstract][Full Text] [Related]
15.
Wang Q; Guo M; Liu Y; Xu M; Shi L; Li X; Zhao J; Zhang H; Wang G; Chen W
Nutrients; 2022 Mar; 14(6):. PubMed ID: 35334879
[TBL] [Abstract][Full Text] [Related]
16. Deficiency of PSRC1 accelerates atherosclerosis by increasing TMAO production via manipulating gut microbiota and flavin monooxygenase 3.
Luo T; Guo Z; Liu D; Guo Z; Wu Q; Li Q; Lin R; Chen P; Ou C; Chen M
Gut Microbes; 2022; 14(1):2077602. PubMed ID: 35613310
[TBL] [Abstract][Full Text] [Related]
17. Dietary betaine reduces liver lipid accumulation via improvement of bile acid and trimethylamine-N-oxide metabolism in blunt-snout bream.
Wang F; Xu J; Jakovlić I; Wang WM; Zhao YH
Food Funct; 2019 Oct; 10(10):6675-6689. PubMed ID: 31559407
[TBL] [Abstract][Full Text] [Related]
18. Trimethylamine and Trimethylamine N-Oxide, a Flavin-Containing Monooxygenase 3 (FMO3)-Mediated Host-Microbiome Metabolic Axis Implicated in Health and Disease.
Fennema D; Phillips IR; Shephard EA
Drug Metab Dispos; 2016 Nov; 44(11):1839-1850. PubMed ID: 27190056
[TBL] [Abstract][Full Text] [Related]
19. Gut microbe-derived metabolite trimethylamine N-oxide accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis.
Yang W; Zhang S; Zhu J; Jiang H; Jia D; Ou T; Qi Z; Zou Y; Qian J; Sun A; Ge J
J Mol Cell Cardiol; 2019 Sep; 134():119-130. PubMed ID: 31299216
[TBL] [Abstract][Full Text] [Related]
20. The roles of trimethylamine-N-oxide in atherosclerosis and its potential therapeutic aspect: A literature review.
Oktaviono YH; Dyah Lamara A; Saputra PBT; Arnindita JN; Pasahari D; Saputra ME; Suasti NMA
Biomol Biomed; 2023 Nov; 23(6):936-948. PubMed ID: 37337893
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
