BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

114 related articles for article (PubMed ID: 32338509)

  • 21. Negative allosteric modulators of cannabinoid receptor 2: protein modeling, binding site identification and molecular dynamics simulations in the presence of an orthosteric agonist.
    Pandey P; Roy KK; Doerksen RJ
    J Biomol Struct Dyn; 2020 Jan; 38(1):32-47. PubMed ID: 30652534
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Free fatty acid receptor 1 (FFAR1/GPR40) signaling affects insulin secretion by enhancing mitochondrial respiration during palmitate exposure.
    Kristinsson H; Bergsten P; Sargsyan E
    Biochim Biophys Acta; 2015 Dec; 1853(12):3248-57. PubMed ID: 26408932
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Suppression of free fatty acid receptor 1 expression in pancreatic β-cells in obese type 2 diabetic db/db mice: a potential role of pancreatic and duodenal homeobox factor 1.
    Kohara K; Obata A; Kimura T; Shimoda M; Moriuchi S; Okauchi S; Hirukawa H; Mune T; Kaku K; Kaneto H
    Endocr J; 2019 Jan; 66(1):43-50. PubMed ID: 30333365
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Discovery of novel agonists and antagonists of the free fatty acid receptor 1 (FFAR1) using virtual screening.
    Tikhonova IG; Sum CS; Neumann S; Engel S; Raaka BM; Costanzi S; Gershengorn MC
    J Med Chem; 2008 Feb; 51(3):625-33. PubMed ID: 18193825
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Effect of hydrophobic and hydrogen bonding interactions on the potency of ß-alanine analogs of G-protein coupled glucagon receptor inhibitors.
    Venugopal PP; Das BK; Soorya E; Chakraborty D
    Proteins; 2020 Feb; 88(2):327-344. PubMed ID: 31443129
    [TBL] [Abstract][Full Text] [Related]  

  • 26. How Does Agonist and Antagonist Binding Lead to Different Conformational Ensemble Equilibria of the κ-Opioid Receptor: Insight from Long-Time Gaussian Accelerated Molecular Dynamics Simulation.
    An X; Bai Q; Bing Z; Zhou S; Shi D; Liu H; Yao X
    ACS Chem Neurosci; 2019 Mar; 10(3):1575-1584. PubMed ID: 30372027
    [TBL] [Abstract][Full Text] [Related]  

  • 27. 20-HETE promotes glucose-stimulated insulin secretion in an autocrine manner through FFAR1.
    Tunaru S; Bonnavion R; Brandenburger I; Preussner J; Thomas D; Scholich K; Offermanns S
    Nat Commun; 2018 Jan; 9(1):177. PubMed ID: 29330456
    [TBL] [Abstract][Full Text] [Related]  

  • 28. A Selectivity Study of FFAR4/FFAR1 Agonists by Molecular Modeling.
    Zhang X; Sun H; Wen X; Yuan H
    J Chem Inf Model; 2019 Oct; 59(10):4467-4474. PubMed ID: 31580060
    [TBL] [Abstract][Full Text] [Related]  

  • 29. FFAR1 is involved in both the acute and chronic effects of palmitate on insulin secretion.
    Kristinsson H; Smith DM; Bergsten P; Sargsyan E
    Endocrinology; 2013 Nov; 154(11):4078-88. PubMed ID: 24035997
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Insights into adenosine A2A receptor activation through cooperative modulation of agonist and allosteric lipid interactions.
    Bruzzese A; Dalton JAR; Giraldo J
    PLoS Comput Biol; 2020 Apr; 16(4):e1007818. PubMed ID: 32298258
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Can Ligands of Different Functional Types Induce Distinct Dynamics in G Protein-Coupled Receptors?
    Chen YH; Lin JH
    Curr Top Med Chem; 2017; 17(21):2370-2380. PubMed ID: 28355999
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Activation of free fatty acid receptor 1 improves hepatic steatosis through a p38-dependent pathway.
    Ou HY; Wu HT; Lu FH; Su YC; Hung HC; Wu JS; Yang YC; Wu CL; Chang CJ
    J Mol Endocrinol; 2014 Oct; 53(2):165-74. PubMed ID: 25008074
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands.
    Wilczynski A; Wang XS; Joseph CG; Xiang Z; Bauzo RM; Scott JW; Sorensen NB; Shaw AM; Millard WJ; Richards NG; Haskell-Luevano C
    J Med Chem; 2004 Apr; 47(9):2194-207. PubMed ID: 15084118
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Recent Insights from Molecular Dynamics Simulations for G Protein-Coupled Receptor Drug Discovery.
    Zou Y; Ewalt J; Ng HL
    Int J Mol Sci; 2019 Aug; 20(17):. PubMed ID: 31470676
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Dysfunctional GPR40/FFAR1 signaling exacerbates pain behavior in mice.
    Nakamoto K; Aizawa F; Miyagi K; Yamashita T; Mankura M; Koyama Y; Kasuya F; Hirasawa A; Kurihara T; Miyata A; Tokuyama S
    PLoS One; 2017; 12(7):e0180610. PubMed ID: 28723961
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Agonist-induced conformational changes in bovine rhodopsin: insight into activation of G-protein-coupled receptors.
    Bhattacharya S; Hall SE; Vaidehi N
    J Mol Biol; 2008 Oct; 382(2):539-55. PubMed ID: 18638482
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Conserved Mechanism of Conformational Stability and Dynamics in G-Protein-Coupled Receptors.
    Bhattacharya S; Salomon-Ferrer R; Lee S; Vaidehi N
    J Chem Theory Comput; 2016 Nov; 12(11):5575-5584. PubMed ID: 27709935
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Progress in the discovery and development of small-molecule modulators of G-protein-coupled receptor 40 (GPR40/FFA1/FFAR1): an emerging target for type 2 diabetes.
    Bharate SB; Nemmani KV; Vishwakarma RA
    Expert Opin Ther Pat; 2009 Feb; 19(2):237-64. PubMed ID: 19441920
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Structure-function relationships of the human bitter taste receptor hTAS2R1: insights from molecular modeling studies.
    Dai W; You Z; Zhou H; Zhang J; Hu Y
    J Recept Signal Transduct Res; 2011 Jun; 31(3):229-40. PubMed ID: 21619450
    [TBL] [Abstract][Full Text] [Related]  

  • 40. [Possible involvement of FFAR1 signaling in mouse emotional behaviors through the regulation of brain monoamine releases].
    Kurihara T
    Nihon Yakurigaku Zasshi; 2023; 158(6):454-459. PubMed ID: 37914322
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.