BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

468 related articles for article (PubMed ID: 32339698)

  • 1. Suppression of circadian clock protein cryptochrome 2 promotes osteoarthritis.
    Bekki H; Duffy T; Okubo N; Olmer M; Alvarez-Garcia O; Lamia K; Kay S; Lotz M
    Osteoarthritis Cartilage; 2020 Jul; 28(7):966-976. PubMed ID: 32339698
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dysregulated circadian rhythm pathway in human osteoarthritis: NR1D1 and BMAL1 suppression alters TGF-β signaling in chondrocytes.
    Akagi R; Akatsu Y; Fisch KM; Alvarez-Garcia O; Teramura T; Muramatsu Y; Saito M; Sasho T; Su AI; Lotz MK
    Osteoarthritis Cartilage; 2017 Jun; 25(6):943-951. PubMed ID: 27884645
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Genome-Wide Occupancy Profiling Reveals Critical Roles of FoxO1 in Regulating Extracellular Matrix and Circadian Rhythm Genes in Human Chondrocytes.
    Duffy T; Bekki H; Lotz MK
    Arthritis Rheumatol; 2020 Sep; 72(9):1514-1523. PubMed ID: 32281255
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The circadian clock in murine chondrocytes regulates genes controlling key aspects of cartilage homeostasis.
    Gossan N; Zeef L; Hensman J; Hughes A; Bateman JF; Rowley L; Little CB; Piggins HD; Rattray M; Boot-Handford RP; Meng QJ
    Arthritis Rheum; 2013 Sep; 65(9):2334-45. PubMed ID: 23896777
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cartilage-specific knockout of miRNA-128a expression normalizes the expression of circadian clock genes (CCGs) and mitigates the severity of osteoarthritis.
    Ko JY; Wang FS; Lian WS; Fang HC; Kuo SJ
    Biomed J; 2024 Apr; 47(2):100629. PubMed ID: 37453588
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Catabolic cytokines disrupt the circadian clock and the expression of clock-controlled genes in cartilage via an NFкB-dependent pathway.
    Guo B; Yang N; Borysiewicz E; Dudek M; Williams JL; Li J; Maywood ES; Adamson A; Hastings MH; Bateman JF; White MR; Boot-Handford RP; Meng QJ
    Osteoarthritis Cartilage; 2015 Nov; 23(11):1981-8. PubMed ID: 26521744
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting Cartilage miR-195/497 Cluster for Osteoarthritis Treatment Regulates the Circadian Clock.
    Shi S; Zhang L; Wang Q; Wang Q; Li D; Sun W; Yi C
    Gerontology; 2024; 70(1):59-75. PubMed ID: 37827130
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Distinct and separable roles for endogenous CRY1 and CRY2 within the circadian molecular clockwork of the suprachiasmatic nucleus, as revealed by the Fbxl3(Afh) mutation.
    Anand SN; Maywood ES; Chesham JE; Joynson G; Banks GT; Hastings MH; Nolan PM
    J Neurosci; 2013 Apr; 33(17):7145-53. PubMed ID: 23616524
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CHRONO and DEC1/DEC2 compensate for lack of CRY1/CRY2 in expression of coherent circadian rhythm but not in generation of circadian oscillation in the neonatal mouse SCN.
    Ono D; Honma KI; Schmal C; Takumi T; Kawamoto T; Fujimoto K; Kato Y; Honma S
    Sci Rep; 2021 Sep; 11(1):19240. PubMed ID: 34584158
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Deregulated expression of cryptochrome genes in human colorectal cancer.
    Mazzoccoli G; Colangelo T; Panza A; Rubino R; De Cata A; Tiberio C; Valvano MR; Pazienza V; Merla G; Augello B; Trombetta D; Storlazzi CT; Macchia G; Gentile A; Tavano F; Vinciguerra M; Bisceglia G; Rosato V; Colantuoni V; Sabatino L; Piepoli A
    Mol Cancer; 2016 Jan; 15():6. PubMed ID: 26768731
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of heterozygous and homozygous alleles in cryptochrome-deficient mice.
    Oda Y; Takasu NN; Ohno SN; Shirakawa Y; Sugimura M; Nakamura TJ; Nakamura W
    Neurosci Lett; 2022 Feb; 772():136415. PubMed ID: 34954114
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential expression of GADD45beta in normal and osteoarthritic cartilage: potential role in homeostasis of articular chondrocytes.
    Ijiri K; Zerbini LF; Peng H; Otu HH; Tsuchimochi K; Otero M; Dragomir C; Walsh N; Bierbaum BE; Mattingly D; van Flandern G; Komiya S; Aigner T; Libermann TA; Goldring MB
    Arthritis Rheum; 2008 Jul; 58(7):2075-87. PubMed ID: 18576389
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Postnatal constant light compensates Cryptochrome1 and 2 double deficiency for disruption of circadian behavioral rhythms in mice under constant dark.
    Ono D; Honma S; Honma K
    PLoS One; 2013; 8(11):e80615. PubMed ID: 24278295
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The chondrocyte clock gene Bmal1 controls cartilage homeostasis and integrity.
    Dudek M; Gossan N; Yang N; Im HJ; Ruckshanthi JP; Yoshitane H; Li X; Jin D; Wang P; Boudiffa M; Bellantuono I; Fukada Y; Boot-Handford RP; Meng QJ
    J Clin Invest; 2016 Jan; 126(1):365-76. PubMed ID: 26657859
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MicroRNA-34a-5p Promotes Joint Destruction During Osteoarthritis.
    Endisha H; Datta P; Sharma A; Nakamura S; Rossomacha E; Younan C; Ali SA; Tavallaee G; Lively S; Potla P; Shestopaloff K; Rockel JS; Krawetz R; Mahomed NN; Jurisica I; Gandhi R; Kapoor M
    Arthritis Rheumatol; 2021 Mar; 73(3):426-439. PubMed ID: 33034147
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cry1-/- circadian rhythmicity depends on SCN intercellular coupling.
    Evans JA; Pan H; Liu AC; Welsh DK
    J Biol Rhythms; 2012 Dec; 27(6):443-52. PubMed ID: 23223370
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Critical cholangiocarcinogenesis control by cryptochrome clock genes.
    Mteyrek A; Filipski E; Guettier C; Oklejewicz M; van der Horst GT; Okyar A; Lévi F
    Int J Cancer; 2017 Jun; 140(11):2473-2483. PubMed ID: 28224616
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The circadian clock: a central mediator of cartilage maintenance and osteoarthritis development?
    Poulsen RC; Hearn JI; Dalbeth N
    Rheumatology (Oxford); 2021 Jul; 60(7):3048-3057. PubMed ID: 33630038
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Loss of circadian rhythm and light-induced suppression of pineal melatonin levels in Cry1 and Cry2 double-deficient mice.
    Yamanaka Y; Suzuki Y; Todo T; Honma K; Honma S
    Genes Cells; 2010 Oct; 15(10):1063-71. PubMed ID: 20825493
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Clock knockdown attenuated reactive oxygen species-mediated senescence of chondrocytes through restoring autophagic flux.
    Zhong J; Wang B; Wu B; Shang J; Jiang N; Cui A; Chen Y; Xu X; Lu H
    Life Sci; 2021 Mar; 269():119036. PubMed ID: 33450259
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.