164 related articles for article (PubMed ID: 32339950)
1. Transgenic expression of Sag/Rbx2 E3 causes early stage tumor promotion, late stage cytogenesis and acinar loss in the Kras-PDAC model.
Zhang Q; Wei D; Tan M; Li H; Morgan MA; Sun Y
Neoplasia; 2020 Apr; 22(6):242-252. PubMed ID: 32339950
[TBL] [Abstract][Full Text] [Related]
2. Depletion of SAG/RBX2 E3 ubiquitin ligase suppresses prostate tumorigenesis via inactivation of the PI3K/AKT/mTOR axis.
Tan M; Xu J; Siddiqui J; Feng F; Sun Y
Mol Cancer; 2016 Dec; 15(1):81. PubMed ID: 27955654
[TBL] [Abstract][Full Text] [Related]
3. The Sag-Shoc2 axis regulates conversion of mPanINs to cystic lesions in Kras pancreatic tumor model.
Tan M; Chang Y; Liu X; Li H; Tang Z; Nyati MK; Sun Y
Cell Rep; 2022 Dec; 41(12):111837. PubMed ID: 36543126
[TBL] [Abstract][Full Text] [Related]
4. Inactivation of Sag/Rbx2/Roc2 e3 ubiquitin ligase triggers senescence and inhibits kras-induced immortalization.
Tan M; Li H; Sun Y
Neoplasia; 2015 Jan; 17(1):114-23. PubMed ID: 25622904
[TBL] [Abstract][Full Text] [Related]
5. Inactivation of SAG/RBX2 E3 ubiquitin ligase suppresses KrasG12D-driven lung tumorigenesis.
Li H; Tan M; Jia L; Wei D; Zhao Y; Chen G; Xu J; Zhao L; Thomas D; Beer DG; Sun Y
J Clin Invest; 2014 Feb; 124(2):835-46. PubMed ID: 24430184
[TBL] [Abstract][Full Text] [Related]
6. Functional characterization of SAG/RBX2/ROC2/RNF7, an antioxidant protein and an E3 ubiquitin ligase.
Sun Y; Li H
Protein Cell; 2013 Feb; 4(2):103-16. PubMed ID: 23136067
[TBL] [Abstract][Full Text] [Related]
7. Erbin is a novel substrate of the Sag-βTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis.
Xie CM; Wei D; Zhao L; Marchetto S; Mei L; Borg JP; Sun Y
J Cell Biol; 2015 Jun; 209(5):721-37. PubMed ID: 26056141
[TBL] [Abstract][Full Text] [Related]
8. mTORC1 and mTORC2 Converge on the Arp2/3 Complex to Promote Kras
Zhao Y; Schoeps B; Yao D; Zhang Z; Schuck K; Tissen V; Jäger C; Schlitter AM; van der Kammen R; Ludwig C; D'Haese JG; Raulefs S; Maeritz N; Shen S; Zou X; Krüger A; Kleeff J; Michalski CW; Friess H; Innocenti M; Kong B
Gastroenterology; 2021 Apr; 160(5):1755-1770.e17. PubMed ID: 33388318
[TBL] [Abstract][Full Text] [Related]
9. The UBE2F-CRL5
Chang Y; Chen Q; Li H; Xu J; Tan M; Xiong X; Sun Y
Dev Cell; 2024 May; 59(10):1317-1332.e5. PubMed ID: 38574733
[TBL] [Abstract][Full Text] [Related]
10. Oncogenic KRAS Reduces Expression of FGF21 in Acinar Cells to Promote Pancreatic Tumorigenesis in Mice on a High-Fat Diet.
Luo Y; Yang Y; Liu M; Wang D; Wang F; Bi Y; Ji J; Li S; Liu Y; Chen R; Huang H; Wang X; Swidnicka-Siergiejko AK; Janowitz T; Beyaz S; Wang G; Xu S; Bialkowska AB; Luo CK; Pin CL; Liang G; Lu X; Wu M; Shroyer KR; Wolff RA; Plunkett W; Ji B; Li Z; Li E; Li X; Yang VW; Logsdon CD; Abbruzzese JL; Lu W
Gastroenterology; 2019 Nov; 157(5):1413-1428.e11. PubMed ID: 31352001
[TBL] [Abstract][Full Text] [Related]
11. Validation of SAG/RBX2/ROC2 E3 ubiquitin ligase as an anticancer and radiosensitizing target.
Jia L; Yang J; Hao X; Zheng M; He H; Xiong X; Xu L; Sun Y
Clin Cancer Res; 2010 Feb; 16(3):814-24. PubMed ID: 20103673
[TBL] [Abstract][Full Text] [Related]
12. Hes1 plays an essential role in Kras-driven pancreatic tumorigenesis.
Nishikawa Y; Kodama Y; Shiokawa M; Matsumori T; Marui S; Kuriyama K; Kuwada T; Sogabe Y; Kakiuchi N; Tomono T; Mima A; Morita T; Ueda T; Tsuda M; Yamauchi Y; Sakuma Y; Ota Y; Maruno T; Uza N; Uesugi M; Kageyama R; Chiba T; Seno H
Oncogene; 2019 May; 38(22):4283-4296. PubMed ID: 30705405
[TBL] [Abstract][Full Text] [Related]
13. GRP78 haploinsufficiency suppresses acinar-to-ductal metaplasia, signaling, and mutant
Shen J; Ha DP; Zhu G; Rangel DF; Kobielak A; Gill PS; Groshen S; Dubeau L; Lee AS
Proc Natl Acad Sci U S A; 2017 May; 114(20):E4020-E4029. PubMed ID: 28461470
[TBL] [Abstract][Full Text] [Related]
14. ANGPTL4 accelerates KRAS
Yan HH; Jung KH; Lee JE; Son MK; Fang Z; Park JH; Kim SJ; Kim JY; Lim JH; Hong SS
Cancer Lett; 2021 Oct; 519():185-198. PubMed ID: 34311032
[TBL] [Abstract][Full Text] [Related]
15. Endothelial deletion of Sag/Rbx2/Roc2 E3 ubiquitin ligase causes embryonic lethality and blocks tumor angiogenesis.
Tan M; Li H; Sun Y
Oncogene; 2014 Oct; 33(44):5211-20. PubMed ID: 24213570
[TBL] [Abstract][Full Text] [Related]
16. Acinar-to-Ductal Metaplasia Induced by Transforming Growth Factor Beta Facilitates KRAS
Chuvin N; Vincent DF; Pommier RM; Alcaraz LB; Gout J; Caligaris C; Yacoub K; Cardot V; Roger E; Kaniewski B; Martel S; Cintas C; Goddard-Léon S; Colombe A; Valantin J; Gadot N; Servoz E; Morton J; Goddard I; Couvelard A; Rebours V; Guillermet J; Sansom OJ; Treilleux I; Valcourt U; Sentis S; Dubus P; Bartholin L
Cell Mol Gastroenterol Hepatol; 2017 Sep; 4(2):263-282. PubMed ID: 28752115
[TBL] [Abstract][Full Text] [Related]
17. miR-802 Suppresses Acinar-to-Ductal Reprogramming During Early Pancreatitis and Pancreatic Carcinogenesis.
Ge W; Goga A; He Y; Silva PN; Hirt CK; Herrmanns K; Guccini I; Godbersen S; Schwank G; Stoffel M
Gastroenterology; 2022 Jan; 162(1):269-284. PubMed ID: 34547282
[TBL] [Abstract][Full Text] [Related]
18. SAG/ROC2/RBX2 E3 ligase promotes UVB-induced skin hyperplasia, but not skin tumors, by simultaneously targeting c-Jun/AP-1 and p27.
He H; Gu Q; Zheng M; Normolle D; Sun Y
Carcinogenesis; 2008 Apr; 29(4):858-65. PubMed ID: 18258608
[TBL] [Abstract][Full Text] [Related]
19. Maintenance of acinar cell organization is critical to preventing Kras-induced acinar-ductal metaplasia.
Shi G; DiRenzo D; Qu C; Barney D; Miley D; Konieczny SF
Oncogene; 2013 Apr; 32(15):1950-8. PubMed ID: 22665051
[TBL] [Abstract][Full Text] [Related]
20. Docking Protein p130Cas Regulates Acinar to Ductal Metaplasia During Pancreatic Adenocarcinoma Development and Pancreatitis.
Costamagna A; Natalini D; Camacho Leal MDP; Simoni M; Gozzelino L; Cappello P; Novelli F; Ambrogio C; Defilippi P; Turco E; Giovannetti E; Hirsch E; Cabodi S; Martini M
Gastroenterology; 2022 Apr; 162(4):1242-1255.e11. PubMed ID: 34922945
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]