These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 32340773)

  • 1. Design and synthesis of novel proline based factor XIa selective inhibitors as leads for potential new anticoagulants.
    Hussain Z; Cooke AJ; Neelamkavil S; Brown L; Carswell E; Geissler WM; Guo Z; Hawes B; Kelly TM; Kiyoi Y; Lai K; Lesburg C; Pow E; Zang Y; Wood HB; Edmondson SD; Liu W
    Bioorg Med Chem Lett; 2020 Aug; 30(16):127072. PubMed ID: 32340773
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, and biological evaluation of peptidomimetic inhibitors of factor XIa as novel anticoagulants.
    Lin J; Deng H; Jin L; Pandey P; Quinn J; Cantin S; Rynkiewicz MJ; Gorga JC; Bibbins F; Celatka CA; Nagafuji P; Bannister TD; Meyers HV; Babine RE; Hayward NJ; Weaver D; Benjamin H; Stassen F; Abdel-Meguid SS; Strickler JE
    J Med Chem; 2006 Dec; 49(26):7781-91. PubMed ID: 17181160
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fragment-Based Lead Generation of 5-Phenyl-1
    Wei Q; Zheng Z; Zhang S; Zheng X; Meng F; Yuan J; Xu Y; Huang C
    Molecules; 2018 Aug; 23(8):. PubMed ID: 30103465
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and in vitro biological evaluation of aryl boronic acids as potential inhibitors of factor XIa.
    Lazarova TI; Jin L; Rynkiewicz M; Gorga JC; Bibbins F; Meyers HV; Babine R; Strickler J
    Bioorg Med Chem Lett; 2006 Oct; 16(19):5022-7. PubMed ID: 16876411
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design and synthesis of macrocyclic indoles targeting blood coagulation cascade Factor XIa.
    Hanessian S; Larsson A; Fex T; Knecht W; Blomberg N
    Bioorg Med Chem Lett; 2010 Dec; 20(23):6925-8. PubMed ID: 21035339
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and biological evaluation of novel FXIa inhibitors with 2-phenyl-1H-imidazole-5-carboxamide moiety as P1 fragment.
    Lei Y; Zhang B; Zhang Y; Dai X; Duan Y; Mao Q; Gao J; Yang Y; Bao Z; Fu X; Ping K; Yan C; Mou Y; Wang S
    Eur J Med Chem; 2021 Aug; 220():113437. PubMed ID: 33894565
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of Benzyl Tetraphosphonate Derivative as Inhibitor of Human Factor Xia.
    Kar S; Mottamal M; Al-Horani RA
    ChemistryOpen; 2020 Nov; 9(11):1161-1172. PubMed ID: 33204588
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of Chromen-7-yl Furan-2-Carboxylate as a Potent and Selective Factor XIa Inhibitor.
    Obaidullah AJ; Al-Horani RA
    Cardiovasc Hematol Agents Med Chem; 2017 Nov; 15(1):40-48. PubMed ID: 28552062
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of a Parenteral Small Molecule Coagulation Factor XIa Inhibitor Clinical Candidate (BMS-962212).
    Pinto DJP; Orwat MJ; Smith LM; Quan ML; Lam PYS; Rossi KA; Apedo A; Bozarth JM; Wu Y; Zheng JJ; Xin B; Toussaint N; Stetsko P; Gudmundsson O; Maxwell B; Crain EJ; Wong PC; Lou Z; Harper TW; Chacko SA; Myers JE; Sheriff S; Zhang H; Hou X; Mathur A; Seiffert DA; Wexler RR; Luettgen JM; Ewing WR
    J Med Chem; 2017 Dec; 60(23):9703-9723. PubMed ID: 29077405
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Apixaban, a direct factor Xa inhibitor, inhibits tissue-factor induced human platelet aggregation in vitro: comparison with direct inhibitors of factor VIIa, XIa and thrombin.
    Wong PC; Jiang X
    Thromb Haemost; 2010 Aug; 104(2):302-10. PubMed ID: 20589316
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-based design of inhibitors of coagulation factor XIa with novel P1 moieties.
    Pinto DJ; Smallheer JM; Corte JR; Austin EJ; Wang C; Fang T; Smith LM; Rossi KA; Rendina AR; Bozarth JM; Zhang G; Wei A; Ramamurthy V; Sheriff S; Myers JE; Morin PE; Luettgen JM; Seiffert DA; Quan ML; Wexler RR
    Bioorg Med Chem Lett; 2015 Apr; 25(7):1635-42. PubMed ID: 25728130
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pyridazine and pyridazinone derivatives as potent and selective factor XIa inhibitors.
    Hu Z; Wang C; Han W; Rossi KA; Bozarth JM; Wu Y; Sheriff S; Myers JE; Luettgen JM; Seiffert DA; Wexler RR; Quan ML
    Bioorg Med Chem Lett; 2018 Apr; 28(6):987-992. PubMed ID: 29501396
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Macrocyclic factor XIa inhibitors.
    Wang C; Corte JR; Rossi KA; Bozarth JM; Wu Y; Sheriff S; Myers JE; Luettgen JM; Seiffert DA; Wexler RR; Quan ML
    Bioorg Med Chem Lett; 2017 Sep; 27(17):4056-4060. PubMed ID: 28780160
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo without enhanced risk of bleeding.
    Al-Horani RA; Abdelfadiel EI; Afosah DK; Morla S; Sistla JC; Mohammed B; Martin EJ; Sakagami M; Brophy DF; Desai UR
    J Thromb Haemost; 2019 Dec; 17(12):2110-2122. PubMed ID: 31397071
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A simple, general approach of allosteric coagulation enzyme inhibition through monosulfated hydrophobic scaffolds.
    Sidhu PS; Zhou Q; Desai UR
    Bioorg Med Chem Lett; 2014 Dec; 24(24):5716-5720. PubMed ID: 25453807
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Allosteric inhibition of human factor XIa: discovery of monosulfated benzofurans as a class of promising inhibitors.
    Argade MD; Mehta AY; Sarkar A; Desai UR
    J Med Chem; 2014 Apr; 57(8):3559-69. PubMed ID: 24666186
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sulfonated non-saccharide molecules and human factor XIa: Enzyme inhibition and computational studies.
    Al-Horani RA; Parsaeian E; Mohammad M; Mottamal M
    Chem Biol Drug Des; 2022 Jul; 100(1):64-79. PubMed ID: 35377529
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Factor XIa inhibitors: A review of the patent literature.
    Al-Horani RA; Desai UR
    Expert Opin Ther Pat; 2016; 26(3):323-45. PubMed ID: 26881476
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Orally bioavailable pyridine and pyrimidine-based Factor XIa inhibitors: Discovery of the methyl N-phenyl carbamate P2 prime group.
    Corte JR; Fang T; Pinto DJ; Orwat MJ; Rendina AR; Luettgen JM; Rossi KA; Wei A; Ramamurthy V; Myers JE; Sheriff S; Narayanan R; Harper TW; Zheng JJ; Li YX; Seiffert DA; Wexler RR; Quan ML
    Bioorg Med Chem; 2016 May; 24(10):2257-72. PubMed ID: 27073051
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Allosteric inhibition of factor XIa. Sulfated non-saccharide glycosaminoglycan mimetics as promising anticoagulants.
    Al-Horani RA; Gailani D; Desai UR
    Thromb Res; 2015 Aug; 136(2):379-87. PubMed ID: 25935648
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.