These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 32340773)

  • 21. Factor XIa Inhibitors as New Anticoagulants.
    Quan ML; Pinto DJP; Smallheer JM; Ewing WR; Rossi KA; Luettgen JM; Seiffert DA; Wexler RR
    J Med Chem; 2018 Sep; 61(17):7425-7447. PubMed ID: 29775297
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Designing allosteric inhibitors of factor XIa. Lessons from the interactions of sulfated pentagalloylglucopyranosides.
    Al-Horani RA; Desai UR
    J Med Chem; 2014 Jun; 57(11):4805-18. PubMed ID: 24844380
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Fasxiator, a novel factor XIa inhibitor from snake venom, and its site-specific mutagenesis to improve potency and selectivity.
    Chen W; Carvalho LP; Chan MY; Kini RM; Kang TS
    J Thromb Haemost; 2015 Feb; 13(2):248-61. PubMed ID: 25418421
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Targeting the S2 Subsite Enables the Structure-Based Discovery of Novel Highly Selective Factor XIa Inhibitors.
    Yao N; Jia Z; Tian Y; Hou S; Yang X; Han J; Duan Y; Liao C; Kong Y; Xie Z
    J Med Chem; 2022 Mar; 65(5):4318-4334. PubMed ID: 35220720
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Recent advances in the discovery and development of factor XI/XIa inhibitors.
    Al-Horani RA; Afosah DK
    Med Res Rev; 2018 Sep; 38(6):1974-2023. PubMed ID: 29727017
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Mechanisms and specificity of factor XIa and trypsin inhibition by protease nexin 2 and basic pancreatic trypsin inhibitor.
    Navaneetham D; Sinha D; Walsh PN
    J Biochem; 2010 Oct; 148(4):467-79. PubMed ID: 20647553
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Structure-Based Design of Macrocyclic Factor XIa Inhibitors: Discovery of the Macrocyclic Amide Linker.
    Corte JR; Fang T; Osuna H; Pinto DJ; Rossi KA; Myers JE; Sheriff S; Lou Z; Zheng JJ; Harper TW; Bozarth JM; Wu Y; Luettgen JM; Seiffert DA; Decicco CP; Wexler RR; Quan ML
    J Med Chem; 2017 Feb; 60(3):1060-1075. PubMed ID: 28085275
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Discovery of Potent and Orally Bioavailable Pyridine N-Oxide-Based Factor XIa Inhibitors through Exploiting Nonclassical Interactions.
    Xu G; Liu Z; Wang X; Lu T; DesJarlais RL; Thieu T; Zhang J; Devine ZH; Du F; Li Q; Milligan CM; Shaffer P; Cedervall PE; Spurlino JC; Stratton CF; Pietrak B; Szewczuk LM; Wong V; Steele RA; Bruinzeel W; Chintala M; Silva J; Gaul MD; Macielag MJ; Nargund R
    J Med Chem; 2022 Aug; 65(15):10419-10440. PubMed ID: 35862732
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Preparation of L-proline based aeruginosin 298-A analogs: optimization of the P1-moiety.
    Wang G; Goyal N; Hopkinson B
    Bioorg Med Chem Lett; 2009 Jul; 19(14):3798-803. PubMed ID: 19447619
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Generation and characterization of aptamers targeting factor XIa.
    Woodruff RS; Ivanov I; Verhamme IM; Sun MF; Gailani D; Sullenger BA
    Thromb Res; 2017 Aug; 156():134-141. PubMed ID: 28644959
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Potent, Orally Bioavailable, and Efficacious Macrocyclic Inhibitors of Factor XIa. Discovery of Pyridine-Based Macrocycles Possessing Phenylazole Carboxamide P1 Groups.
    Corte JR; Pinto DJP; Fang T; Osuna H; Yang W; Wang Y; Lai A; Clark CG; Sun JH; Rampulla R; Mathur A; Kaspady M; Neithnadka PR; Li YC; Rossi KA; Myers JE; Sheriff S; Lou Z; Harper TW; Huang C; Zheng JJ; Bozarth JM; Wu Y; Wong PC; Crain EJ; Seiffert DA; Luettgen JM; Lam PYS; Wexler RR; Ewing WR
    J Med Chem; 2020 Jan; 63(2):784-803. PubMed ID: 31833761
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Sulfated pentagalloylglucoside is a potent, allosteric, and selective inhibitor of factor XIa.
    Al-Horani RA; Ponnusamy P; Mehta AY; Gailani D; Desai UR
    J Med Chem; 2013 Feb; 56(3):867-78. PubMed ID: 23316863
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Pyridine and pyridinone-based factor XIa inhibitors.
    Corte JR; Fang T; Hangeland JJ; Friends TJ; Rendina AR; Luettgen JM; Bozarth JM; Barbera FA; Rossi KA; Wei A; Ramamurthy V; Morin PE; Seiffert DA; Wexler RR; Quan ML
    Bioorg Med Chem Lett; 2015 Feb; 25(4):925-30. PubMed ID: 25592713
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Orally bioavailable amine-linked macrocyclic inhibitors of factor XIa.
    Fang T; Corte JR; Gilligan PJ; Jeon Y; Osuna H; Rossi KA; Myers JE; Sheriff S; Lou Z; Zheng JJ; Harper TW; Bozarth JM; Wu Y; Luettgen JM; Seiffert DA; Wexler RR; Lam PYS
    Bioorg Med Chem Lett; 2020 Feb; 30(4):126949. PubMed ID: 31932224
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Synthesis, Docking, and In Vitro Anticoagulant Activity Assay of Hybrid Derivatives of Pyrrolo[3,2,1-
    Novichikhina N; Ilin I; Tashchilova A; Sulimov A; Kutov D; Ledenyova I; Krysin M; Shikhaliev K; Gantseva A; Gantseva E; Podoplelova N; Sulimov V
    Molecules; 2020 Apr; 25(8):. PubMed ID: 32325823
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Development of Selective FXIa Inhibitors Based on Cyclic Peptides and Their Application for Safe Anticoagulation.
    Carle V; Wu Y; Mukherjee R; Kong XD; Rogg C; Laurent Q; Cecere E; Villequey C; Konakalla MS; Maric T; Lamers C; Díaz-Perlas C; Butler K; Goto J; Stegmayr B; Heinis C
    J Med Chem; 2021 May; 64(10):6802-6813. PubMed ID: 33974422
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Thrombogenic potential of picomolar coagulation factor XIa is mediated by thrombin wave propagation.
    Parunov LA; Liang Y; Lu Q; Shibeko AM; Tucker EI; Lee TK; Ataullakhanov FI; Scott DE; Ovanesov MV
    Blood Adv; 2023 Jun; 7(11):2622-2631. PubMed ID: 36724509
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Novel phenylalanine derived diamides as Factor XIa inhibitors.
    Smith LM; Orwat MJ; Hu Z; Han W; Wang C; Rossi KA; Gilligan PJ; Pabbisetty KB; Osuna H; Corte JR; Rendina AR; Luettgen JM; Wong PC; Narayanan R; Harper TW; Bozarth JM; Crain EJ; Wei A; Ramamurthy V; Morin PE; Xin B; Zheng J; Seiffert DA; Quan ML; Lam PYS; Wexler RR; Pinto DJP
    Bioorg Med Chem Lett; 2016 Jan; 26(2):472-478. PubMed ID: 26704266
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Structural and mutational analyses of the molecular interactions between the catalytic domain of factor XIa and the Kunitz protease inhibitor domain of protease nexin 2.
    Navaneetham D; Jin L; Pandey P; Strickler JE; Babine RE; Abdel-Meguid SS; Walsh PN
    J Biol Chem; 2005 Oct; 280(43):36165-75. PubMed ID: 16085935
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Factor XIa Inhibitors in Anticoagulation Therapy: Recent Advances and Perspectives.
    Xie Z; Meng Z; Yang X; Duan Y; Wang Q; Liao C
    J Med Chem; 2023 Apr; 66(8):5332-5363. PubMed ID: 37037122
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.