204 related articles for article (PubMed ID: 32344183)
1. Synthesis and anticancer evaluation of novel 1H-benzo[d]imidazole derivatives of dehydroabietic acid as PI3Kα inhibitors.
Yang YQ; Chen H; Liu QS; Sun Y; Gu W
Bioorg Chem; 2020 Jul; 100():103845. PubMed ID: 32344183
[TBL] [Abstract][Full Text] [Related]
2. Development of novel chromeno[4,3-c]pyrazol-4(2H)-one derivates containing piperazine as inhibitors of PI3Kα.
Yin Y; Zhou Y; Sha S; Wu X; Wang SF; Qiao F; Song ZC; Zhu HL
Bioorg Chem; 2019 Nov; 92():103238. PubMed ID: 31499259
[TBL] [Abstract][Full Text] [Related]
3. Development of novel chromeno[4,3-c]pyrazol-4(2H)-one derivates bearing sulfonylpiperazine as antitumor inhibitors targeting PI3Kα.
Yin Y; Sha S; Wu X; Wang SF; Qiao F; Song ZC; Zhu HL
Eur J Med Chem; 2019 Nov; 182():111630. PubMed ID: 31446244
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis and evaluation of some 1,6-disubstituted-1H-benzo[d]imidazoles derivatives targeted PI3K as anticancer agents.
Ding HW; Yu L; Bai MX; Qin XC; Song MT; Zhao QC
Bioorg Chem; 2019 Dec; 93():103283. PubMed ID: 31585260
[TBL] [Abstract][Full Text] [Related]
5. Ligand-Based Drug Design: Synthesis and Biological Evaluation of Substituted Benzoin Derivatives as Potential Antitumor Agents.
Sabbah DA; Ibrahim AH; Talib WH; Alqaisi KM; Sweidan K; Bardaweel SK; Sheikha GA; Zhong HA; Al-Shalabi E; Khalaf RA; Mubarak MS
Med Chem; 2019; 15(4):417-429. PubMed ID: 30207238
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis and biological evaluation of novel chromeno[4,3-c]pyrazol-4(2H)-one derivates containing sulfonamido as potential PI3Kα inhibitors.
Yin Y; Hu JQ; Wu X; Sha S; Wang SF; Qiao F; Song ZC; Zhu HL
Bioorg Med Chem; 2019 Jun; 27(11):2261-2267. PubMed ID: 31029551
[TBL] [Abstract][Full Text] [Related]
7. Docking Studies and Antiproliferative Activities of 6-(3-aryl-2-propenoyl)-2(3H)- benzoxazolone Derivatives as Novel Inhibitors of Phosphatidylinositol 3-Kinase (PI3Kα).
Bilginer S; Bardaweel SK; Sabbah DA; Gul HI
Anticancer Agents Med Chem; 2021; 21(6):716-724. PubMed ID: 32767959
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and biological evaluation of novel
Chen H; Qiao C; Miao TT; Li AL; Wang WY; Gu W
J Enzyme Inhib Med Chem; 2019 Dec; 34(1):1544-1561. PubMed ID: 31448648
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and antitumor evaluation of (aryl)methyl-amine derivatives of dehydroabietic acid-based B ring-fused-thiazole as potential PI3K/AKT/mTOR signaling pathway inhibitors.
Chen NY; Xie YL; Lu GD; Ye F; Li XY; Huang YW; Huang ML; Chen TY; Li CP
Mol Divers; 2021 May; 25(2):967-979. PubMed ID: 32297120
[TBL] [Abstract][Full Text] [Related]
10. Synthesis, anticancer evaluation and mechanism studies of novel indolequinone derivatives of ursolic acid.
Wang WY; Wu WY; Li AL; Liu QS; Sun Y; Gu W
Bioorg Chem; 2021 Apr; 109():104705. PubMed ID: 33618252
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and Antiproliferative Evaluation of Novel Hybrids of Dehydroabietic Acid Bearing 1,2,3-Triazole Moiety.
Li FY; Huang L; Li Q; Wang X; Ma XL; Jiang CN; Zhou XQ; Duan WG; Lei FH
Molecules; 2019 Nov; 24(22):. PubMed ID: 31752282
[TBL] [Abstract][Full Text] [Related]
12. Structure-Based Design: Synthesis, X-ray Crystallography, and Biological Evaluation of N-Substituted-4-Hydroxy-2-Quinolone-3-Carboxamides as Potential Cytotoxic Agents.
Sabbah DA; Hishmah B; Sweidan K; Bardaweel S; AlDamen M; Zhong HA; Abu Khalaf R; Hasan Ibrahim A; Al-Qirim T; Abu Sheikha G; Mubarak MS
Anticancer Agents Med Chem; 2018; 18(2):263-276. PubMed ID: 28901259
[TBL] [Abstract][Full Text] [Related]
13. Design, synthesis, and biological evaluation of novel 6-(pyridin-3-yl) quinazolin-4(3H)-one derivatives as potential anticancer agents via PI3K inhibition.
Yang H; Li Q; Su M; Luo F; Liu Y; Wang D; Fan Y
Bioorg Med Chem; 2021 Sep; 46():116346. PubMed ID: 34403956
[TBL] [Abstract][Full Text] [Related]
14. Structurally novel PI3Kδ/γ dual inhibitors characterized by a seven-membered spirocyclic spacer: The SARs investigation and PK evaluation.
Tao Q; Chen Y; Liang X; Hu Y; Li J; Fang F; Wang H; Meng C; Liang J; Ma X; Gui S
Eur J Med Chem; 2020 Apr; 191():112143. PubMed ID: 32078865
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis, biological evaluation of 6-(2-amino-1H-benzo[d]imidazole-6-yl)quinazolin-4(3H)-one derivatives as novel anticancer agents with Aurora kinase inhibition.
Fan C; Zhong T; Yang H; Yang Y; Wang D; Yang X; Xu Y; Fan Y
Eur J Med Chem; 2020 Mar; 190():112108. PubMed ID: 32058239
[TBL] [Abstract][Full Text] [Related]
16. Alkylsulfonamide-containing quinazoline derivatives as potent and orally bioavailable PI3Ks inhibitors.
Hei YY; Zhang SQ; Feng Y; Wang J; Duan W; Zhang H; Mao S; Sun H; Xin M
Bioorg Med Chem; 2019 Oct; 27(20):114930. PubMed ID: 31176568
[TBL] [Abstract][Full Text] [Related]
17. Structure optimization, synthesis, and biological evaluation of 6-(2-amino-1H-benzo[d]imidazole-6-yl)-quinazolin-4(3H)-one derivatives as potential multi-targeted anticancer agents via Aurora A/ PI3K/BRD4 inhibition.
Fan Y; Luo F; Su M; Li Q; Zhong T; Xiong L; Li M; Yuan M; Wang D
Bioorg Chem; 2023 Mar; 132():106352. PubMed ID: 36682147
[TBL] [Abstract][Full Text] [Related]
18. Novel 4-aminoquinazoline derivatives induce growth inhibition, cell cycle arrest and apoptosis via PI3Kα inhibition.
Fan YH; Ding HW; Liu DD; Song HR; Xu YN; Wang J
Bioorg Med Chem; 2018 May; 26(8):1675-1685. PubMed ID: 29475582
[TBL] [Abstract][Full Text] [Related]
19. Benzoin Schiff Bases: Design, Synthesis, and Biological Evaluation as Potential Antitumor Agents.
Sabbah DA; Al-Tarawneh F; Talib WH; Sweidan K; Bardaweel SK; Al-Shalabi E; Zhong HA; Abu Sheikha G; Abu Khalaf R; Mubarak MS
Med Chem; 2018; 14(7):695-708. PubMed ID: 29651943
[TBL] [Abstract][Full Text] [Related]
20. Discovery of cinnoline derivatives as potent PI3K inhibitors with antiproliferative activity.
Tian C; Yang C; Wu T; Lu M; Chen Y; Yang Y; Liu X; Ling Y; Deng M; Jia Y; Zhou Y
Bioorg Med Chem Lett; 2021 Sep; 48():128271. PubMed ID: 34284105
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]