193 related articles for article (PubMed ID: 32347987)
1. A method to specifically activate the Klotho promoter by using zinc finger proteins constructed from modular building blocks and from naturally engineered Egr1 transcription factor backbone.
Chen CD; Rudy MA; Zeldich E; Abraham CR
FASEB J; 2020 Jun; 34(6):7234-7246. PubMed ID: 32347987
[TBL] [Abstract][Full Text] [Related]
2. Activation of the Anti-Aging and Cognition-Enhancing Gene Klotho by CRISPR-dCas9 Transcriptional Effector Complex.
Chen CD; Zeldich E; Li Y; Yuste A; Abraham CR
J Mol Neurosci; 2018 Feb; 64(2):175-184. PubMed ID: 29352444
[TBL] [Abstract][Full Text] [Related]
3. Transcriptional activation of the human Klotho gene by epidermal growth factor in HEK293 cells; role of Egr-1.
Choi BH; Kim CG; Lim Y; Lee YH; Shin SY
Gene; 2010 Jan; 450(1-2):121-7. PubMed ID: 19913601
[TBL] [Abstract][Full Text] [Related]
4. Klotho Is a Neuroprotective and Cognition-Enhancing Protein.
Abraham CR; Mullen PC; Tucker-Zhou T; Chen CD; Zeldich E
Vitam Horm; 2016; 101():215-38. PubMed ID: 27125744
[TBL] [Abstract][Full Text] [Related]
5. Effects of intra- and extracellular factors on anti-aging klotho gene expression.
Turan K; Ata P
Genet Mol Res; 2011 Sep; 10(3):2009-23. PubMed ID: 21948763
[TBL] [Abstract][Full Text] [Related]
6. Small-molecule Klotho enhancers as novel treatment of neurodegeneration.
Abraham CR; Chen C; Cuny GD; Glicksman MA; Zeldich E
Future Med Chem; 2012 Sep; 4(13):1671-9. PubMed ID: 22924505
[TBL] [Abstract][Full Text] [Related]
7. Establishment of a cell-based assay to screen regulators for Klotho gene promoter.
Xu ZL; Gao H; Ou-Yang KQ; Cai SX; Hu YH
Acta Pharmacol Sin; 2004 Sep; 25(9):1165-70. PubMed ID: 15339392
[TBL] [Abstract][Full Text] [Related]
8. Early growth response gene 1 (EGR1) regulates heparanase gene transcription in tumor cells.
de Mestre AM; Rao S; Hornby JR; Soe-Htwe T; Khachigian LM; Hulett MD
J Biol Chem; 2005 Oct; 280(42):35136-47. PubMed ID: 16093249
[TBL] [Abstract][Full Text] [Related]
9. The zebrafish egr1 gene encodes a highly conserved, zinc-finger transcriptional regulator.
Drummond IA; Rohwer-Nutter P; Sukhatme VP
DNA Cell Biol; 1994 Sep; 13(9):953-61. PubMed ID: 7917016
[TBL] [Abstract][Full Text] [Related]
10. The zebrafish egr1 gene encodes a highly conserved, zinc-finger transcriptional regulator.
Drummond IA; Rohwer-Nutter P; Sukhatme VP
DNA Cell Biol; 1994 Oct; 13(10):1047-55. PubMed ID: 7945937
[TBL] [Abstract][Full Text] [Related]
11. ZNF300, a recently identified human transcription factor, activates the human IL-2Rβ promoter through the overlapping ZNF300/EGR1 binding site.
Xue L; Qiu H; Ma J; Guo M; Li W
Cell Mol Biol Lett; 2010 Dec; 15(4):530-40. PubMed ID: 20585888
[TBL] [Abstract][Full Text] [Related]
12. Klotho Is Neuroprotective in the Superoxide Dismutase (SOD1
Zeldich E; Chen CD; Boden E; Howat B; Nasse JS; Zeldich D; Lambert AG; Yuste A; Cherry JD; Mathias RM; Ma Q; Lau NC; McKee AC; Hatzipetros T; Abraham CR
J Mol Neurosci; 2019 Oct; 69(2):264-285. PubMed ID: 31250273
[TBL] [Abstract][Full Text] [Related]
13. Structure-function relationships of the soluble form of the antiaging protein Klotho have therapeutic implications for managing kidney disease.
Zhong X; Jagarlapudi S; Weng Y; Ly M; Rouse JC; McClure K; Ishino T; Zhang Y; Sousa E; Cohen J; Tzvetkova B; Cote K; Scarcelli JJ; Johnson K; Palandra J; Apgar JR; Yaddanapudi S; Gonzalez-Villalobos RA; Opsahl AC; Lam K; Yao Q; Duan W; Sievers A; Zhou J; Ferguson D; D'Antona A; Zollner R; Zhu HL; Kriz R; Lin L; Clerin V
J Biol Chem; 2020 Mar; 295(10):3115-3133. PubMed ID: 32005658
[TBL] [Abstract][Full Text] [Related]
14. Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks.
Beerli RR; Segal DJ; Dreier B; Barbas CF
Proc Natl Acad Sci U S A; 1998 Dec; 95(25):14628-33. PubMed ID: 9843940
[TBL] [Abstract][Full Text] [Related]
15. Promoter-targeted phage display selections with preassembled synthetic zinc finger libraries for endogenous gene regulation.
Lund CV; Blancafort P; Popkov M; Barbas CF
J Mol Biol; 2004 Jul; 340(3):599-613. PubMed ID: 15210357
[TBL] [Abstract][Full Text] [Related]
16. Klotho upregulation contributes to the neuroprotection of ligustilide in an Alzheimer's disease mouse model.
Kuang X; Chen YS; Wang LF; Li YJ; Liu K; Zhang MX; Li LJ; Chen C; He Q; Wang Y; Du JR
Neurobiol Aging; 2014 Jan; 35(1):169-78. PubMed ID: 23973442
[TBL] [Abstract][Full Text] [Related]
17. Soluble Klotho regulates bone differentiation by upregulating expression of the transcription factor EGR-1.
Toan NK; Tai NC; Kim SA; Ahn SG
FEBS Lett; 2020 Jan; 594(2):290-300. PubMed ID: 31536138
[TBL] [Abstract][Full Text] [Related]
18. TGFβ-incurred epigenetic aberrations of miRNA and DNA methyltransferase suppress Klotho and potentiate renal fibrosis.
Yin S; Zhang Q; Yang J; Lin W; Li Y; Chen F; Cao W
Biochim Biophys Acta Mol Cell Res; 2017 Jul; 1864(7):1207-1216. PubMed ID: 28285987
[TBL] [Abstract][Full Text] [Related]
19. Chemically regulated zinc finger transcription factors.
Beerli RR; Schopfer U; Dreier B; Barbas CF
J Biol Chem; 2000 Oct; 275(42):32617-27. PubMed ID: 10924515
[TBL] [Abstract][Full Text] [Related]
20. Klotho Restraining Egr1/TLR4/mTOR Axis to Reducing the Expression of Fibrosis and Inflammatory Cytokines in High Glucose Cultured Rat Mesangial Cells.
Wu C; Ma X; Zhou Y; Liu Y; Shao Y; Wang Q
Exp Clin Endocrinol Diabetes; 2019 Oct; 127(9):630-640. PubMed ID: 29890551
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
