These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 32348940)

  • 1. Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method.
    Takaya D; Niwa H; Mikuni J; Nakamura K; Handa N; Tanaka A; Yokoyama S; Honma T
    J Mol Graph Model; 2020 Sep; 99():107599. PubMed ID: 32348940
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Protein-ligand binding affinity prediction of cyclin-dependent kinase-2 inhibitors by dynamically averaged fragment molecular orbital-based interaction energy.
    Takaba K; Watanabe C; Tokuhisa A; Akinaga Y; Ma B; Kanada R; Araki M; Okuno Y; Kawashima Y; Moriwaki H; Kawashita N; Honma T; Fukuzawa K; Tanaka S
    J Comput Chem; 2022 Jul; 43(20):1362-1371. PubMed ID: 35678372
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CaMKK2 kinase domain interacts with the autoinhibitory region through the N-terminal lobe including the RP insert.
    Kylarova S; Psenakova K; Herman P; Obsilova V; Obsil T
    Biochim Biophys Acta Gen Subj; 2018 Oct; 1862(10):2304-2313. PubMed ID: 30053538
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Prediction of cyclin-dependent kinase 2 inhibitor potency using the fragment molecular orbital method.
    Mazanetz MP; Ichihara O; Law RJ; Whittaker M
    J Cheminform; 2011 Jan; 3(1):2. PubMed ID: 21219630
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 14-3-3 protein directly interacts with the kinase domain of calcium/calmodulin-dependent protein kinase kinase (CaMKK2).
    Psenakova K; Petrvalska O; Kylarova S; Lentini Santo D; Kalabova D; Herman P; Obsilova V; Obsil T
    Biochim Biophys Acta Gen Subj; 2018 Jul; 1862(7):1612-1625. PubMed ID: 29649512
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Theoretical Analysis of Activity Cliffs among Benzofuranone-Class Pim1 Inhibitors Using the Fragment Molecular Orbital Method with Molecular Mechanics Poisson-Boltzmann Surface Area (FMO+MM-PBSA) Approach.
    Watanabe C; Watanabe H; Fukuzawa K; Parker LJ; Okiyama Y; Yuki H; Yokoyama S; Nakano H; Tanaka S; Honma T
    J Chem Inf Model; 2017 Dec; 57(12):2996-3010. PubMed ID: 29111719
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Analyzing GPCR-Ligand Interactions with the Fragment Molecular Orbital (FMO) Method.
    Heifetz A; James T; Southey M; Morao I; Fedorov DG; Bodkin MJ; Townsend-Nicholson A
    Methods Mol Biol; 2020; 2114():163-175. PubMed ID: 32016893
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Exploring GPCR-Ligand Interactions with the Fragment Molecular Orbital (FMO) Method.
    Chudyk EI; Sarrat L; Aldeghi M; Fedorov DG; Bodkin MJ; James T; Southey M; Robinson R; Morao I; Heifetz A
    Methods Mol Biol; 2018; 1705():179-195. PubMed ID: 29188563
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Stabilization of Protein-Protein Interactions between CaMKK2 and 14-3-3 by Fusicoccins.
    Lentini Santo D; Petrvalska O; Obsilova V; Ottmann C; Obsil T
    ACS Chem Biol; 2020 Nov; 15(11):3060-3071. PubMed ID: 33146997
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Concurrent regulation of LKB1 and CaMKK2 in the activation of AMPK in castrate-resistant prostate cancer by a well-defined polyherbal mixture with anticancer properties.
    MacDonald AF; Bettaieb A; Donohoe DR; Alani DS; Han A; Zhao Y; Whelan J
    BMC Complement Altern Med; 2018 Jun; 18(1):188. PubMed ID: 29914450
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes.
    Eduful BJ; O'Byrne SN; Temme L; Asquith CRM; Liang Y; Picado A; Pilotte JR; Hossain MA; Wells CI; Zuercher WJ; Catta-Preta CMC; Zonzini Ramos P; Santiago AS; Couñago RM; Langendorf CG; Nay K; Oakhill JS; Pulliam TL; Lin C; Awad D; Willson TM; Frigo DE; Scott JW; Drewry DH
    J Med Chem; 2021 Aug; 64(15):10849-10877. PubMed ID: 34264658
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 14-3-3 protein inhibits CaMKK1 by blocking the kinase active site with its last two C-terminal helices.
    Petrvalska O; Honzejkova K; Koupilova N; Herman P; Obsilova V; Obsil T
    Protein Sci; 2023 Nov; 32(11):e4805. PubMed ID: 37817008
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495.
    Spengler K; Zibrova D; Woods A; Langendorf CG; Scott JW; Carling D; Heller R
    Biochem J; 2020 Sep; 477(17):3453-3469. PubMed ID: 32869834
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Towards good correlation between fragment molecular orbital interaction energies and experimental IC
    Sheng Y; Watanabe H; Maruyama K; Watanabe C; Okiyama Y; Honma T; Fukuzawa K; Tanaka S
    Comput Struct Biotechnol J; 2018; 16():421-434. PubMed ID: 30450166
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) inhibitors: a novel approach in small molecule discovery.
    Devasahayam Arokia Balaya R; Chandrasekaran J; Kanekar S; Kumar Modi P; Dagamajalu S; Gopinathan K; Raju R; Prasad TSK
    J Biomol Struct Dyn; 2023; 41(24):15196-15206. PubMed ID: 37029757
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Using the fluorescent properties of STO-609 as a tool to assist structure-function analyses of recombinant CaMKK2.
    Gerner L; Munack S; Temmerman K; Lawrence-Dörner AM; Besir H; Wilmanns M; Jensen JK; Thiede B; Mills IG; Morth JP
    Biochem Biophys Res Commun; 2016 Jul; 476(2):102-7. PubMed ID: 27178209
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of CaMKK2 in Golgi-associated vesicle trafficking.
    Kennedy G; Gibson O; T O'Hare D; Mills IG; Evergren E
    Biochem Soc Trans; 2023 Feb; 51(1):331-342. PubMed ID: 36815702
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins.
    Langendorf CG; O'Brien MT; Ngoei KRW; McAloon LM; Dhagat U; Hoque A; Ling NXY; Dite TA; Galic S; Loh K; Parker MW; Oakhill JS; Kemp BE; Scott JW
    J Biol Chem; 2020 Nov; 295(48):16239-16250. PubMed ID: 32913128
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Assessment and acceleration of binding energy calculations for protein-ligand complexes by the fragment molecular orbital method.
    Otsuka T; Okimoto N; Taiji M
    J Comput Chem; 2015 Nov; 36(30):2209-18. PubMed ID: 26400829
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Impact of Genetic Variation on Human CaMKK2 Regulation by Ca
    O'Brien MT; Oakhill JS; Ling NX; Langendorf CG; Hoque A; Dite TA; Means AR; Kemp BE; Scott JW
    Sci Rep; 2017 Feb; 7():43264. PubMed ID: 28230171
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.