These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 32359427)

  • 1. Specific Knockdown of α-Synuclein by Peptide-Directed Proteasome Degradation Rescued Its Associated Neurotoxicity.
    Qu J; Ren X; Xue F; He Y; Zhang R; Zheng Y; Huang H; Wang W; Zhang J
    Cell Chem Biol; 2020 Jun; 27(6):751-762.e4. PubMed ID: 32359427
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Distinct alpha-Synuclein species induced by seeding are selectively cleared by the Lysosome or the Proteasome in neuronally differentiated SH-SY5Y cells.
    Pantazopoulou M; Brembati V; Kanellidi A; Bousset L; Melki R; Stefanis L
    J Neurochem; 2021 Mar; 156(6):880-896. PubMed ID: 32869336
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Natural alkaloid harmine promotes degradation of alpha-synuclein via PKA-mediated ubiquitin-proteasome system activation.
    Cai CZ; Zhou HF; Yuan NN; Wu MY; Lee SM; Ren JY; Su HX; Lu JJ; Chen XP; Li M; Tan JQ; Lu JH
    Phytomedicine; 2019 Aug; 61():152842. PubMed ID: 31048127
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lycorine, a natural alkaloid, promotes the degradation of alpha-synuclein via PKA-mediated UPS activation in transgenic Parkinson's disease models.
    Zhu Q; Zhuang XX; Chen JY; Yuan NN; Chen Y; Cai CZ; Tan JQ; Su HX; Lu JH
    Phytomedicine; 2021 Jul; 87():153578. PubMed ID: 34038839
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The role of ubiquitin linkages on alpha-synuclein induced-toxicity in a Drosophila model of Parkinson's disease.
    Lee FK; Wong AK; Lee YW; Wan OW; Chan HY; Chung KK
    J Neurochem; 2009 Jul; 110(1):208-19. PubMed ID: 19457126
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pale body-like inclusion formation and neurodegeneration following depletion of 26S proteasomes in mouse brain neurones are independent of α-synuclein.
    Paine SM; Anderson G; Bedford K; Lawler K; Mayer RJ; Lowe J; Bedford L
    PLoS One; 2013; 8(1):e54711. PubMed ID: 23382946
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tetramethylpyrazine Analogue T-006 Promotes the Clearance of Alpha-synuclein by Enhancing Proteasome Activity in Parkinson's Disease Models.
    Zhou H; Shao M; Guo B; Li C; Lu Y; Yang X; ShengnanLi ; Li H; Zhu Q; Zhong H; Wang Y; Zhang Z; Lu J; Lee SM
    Neurotherapeutics; 2019 Oct; 16(4):1225-1236. PubMed ID: 31313223
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions.
    Chu Y; Dodiya H; Aebischer P; Olanow CW; Kordower JH
    Neurobiol Dis; 2009 Sep; 35(3):385-98. PubMed ID: 19505575
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Overcrowded Crossroads: Mitochondria, Alpha-Synuclein, and the Endo-Lysosomal System Interaction in Parkinson's Disease.
    Lin KJ; Lin KL; Chen SD; Liou CW; Chuang YC; Lin HY; Lin TK
    Int J Mol Sci; 2019 Oct; 20(21):. PubMed ID: 31731450
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lewy body-like α-synuclein aggregates resist degradation and impair macroautophagy.
    Tanik SA; Schultheiss CE; Volpicelli-Daley LA; Brunden KR; Lee VM
    J Biol Chem; 2013 May; 288(21):15194-210. PubMed ID: 23532841
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cathepsin L prevents the accumulation of alpha-synuclein fibrils in the cell.
    Matsuki A; Watanabe Y; Hashimoto S; Hoshino A; Matoba S
    Genes Cells; 2024 Apr; 29(4):328-336. PubMed ID: 38366711
    [TBL] [Abstract][Full Text] [Related]  

  • 12. E46K Mutant α-Synuclein Is Degraded by Both Proteasome and Macroautophagy Pathway.
    Yan JQ; Yuan YH; Chu SF; Li GH; Chen NH
    Molecules; 2018 Nov; 23(11):. PubMed ID: 30388770
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeted degradation of ⍺-synuclein aggregates in Parkinson's disease using the AUTOTAC technology.
    Lee J; Sung KW; Bae EJ; Yoon D; Kim D; Lee JS; Park DH; Park DY; Mun SR; Kwon SC; Kim HY; Min JO; Lee SJ; Suh YH; Kwon YT
    Mol Neurodegener; 2023 Jun; 18(1):41. PubMed ID: 37355598
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Macroautophagy and the proteasome are differently involved in the degradation of alpha-synuclein wild type and mutated A30P in an in vitro inducible model (PC12/TetOn).
    Batelli S; Peverelli E; Rodilossi S; Forloni G; Albani D
    Neuroscience; 2011 Nov; 195(4):128-37. PubMed ID: 21906659
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Distinct roles in vivo for the ubiquitin-proteasome system and the autophagy-lysosomal pathway in the degradation of α-synuclein.
    Ebrahimi-Fakhari D; Cantuti-Castelvetri I; Fan Z; Rockenstein E; Masliah E; Hyman BT; McLean PJ; Unni VK
    J Neurosci; 2011 Oct; 31(41):14508-20. PubMed ID: 21994367
    [TBL] [Abstract][Full Text] [Related]  

  • 16. α-Synuclein fate: proteasome or autophagy?
    Engelender S
    Autophagy; 2012 Mar; 8(3):418-20. PubMed ID: 22361583
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of a highly neurotoxic α-synuclein species inducing mitochondrial damage and mitophagy in Parkinson's disease.
    Grassi D; Howard S; Zhou M; Diaz-Perez N; Urban NT; Guerrero-Given D; Kamasawa N; Volpicelli-Daley LA; LoGrasso P; Lasmézas CI
    Proc Natl Acad Sci U S A; 2018 Mar; 115(11):E2634-E2643. PubMed ID: 29487216
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphorylated alpha-synuclein at Ser-129 is targeted to the proteasome pathway in a ubiquitin-independent manner.
    Machiya Y; Hara S; Arawaka S; Fukushima S; Sato H; Sakamoto M; Koyama S; Kato T
    J Biol Chem; 2010 Dec; 285(52):40732-44. PubMed ID: 20959456
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The vicious cycle between α-synuclein aggregation and autophagic-lysosomal dysfunction.
    Bellomo G; Paciotti S; Gatticchi L; Parnetti L
    Mov Disord; 2020 Jan; 35(1):34-44. PubMed ID: 31729779
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reprint of: revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease-resemblance to the effect of amphetamine drugs of abuse.
    Perfeito R; Cunha-Oliveira T; Rego AC
    Free Radic Biol Med; 2013 Sep; 62():186-201. PubMed ID: 23743292
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.