These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
229 related articles for article (PubMed ID: 32364710)
1. Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing. Chen JL; Zhang P; Abe M; Aikawa H; Zhang L; Frank AJ; Zembryski T; Hubbs C; Park H; Withka J; Steppan C; Rogers L; Cabral S; Pettersson M; Wager TT; Fountain MA; Rumbaugh G; Childs-Disney JL; Disney MD J Am Chem Soc; 2020 May; 142(19):8706-8727. PubMed ID: 32364710 [TBL] [Abstract][Full Text] [Related]
2. Structural determinants for alternative splicing regulation of the MAPT pre-mRNA. Lisowiec J; Magner D; Kierzek E; Lenartowicz E; Kierzek R RNA Biol; 2015; 12(3):330-42. PubMed ID: 25826665 [TBL] [Abstract][Full Text] [Related]
3. Bottom-up design of small molecules that stimulate exon 10 skipping in mutant MAPT pre-mRNA. Luo Y; Disney MD Chembiochem; 2014 Sep; 15(14):2041-4. PubMed ID: 25115866 [TBL] [Abstract][Full Text] [Related]
4. The tau N279K exon 10 splicing mutation recapitulates frontotemporal dementia and parkinsonism linked to chromosome 17 tauopathy in a mouse model. Dawson HN; Cantillana V; Chen L; Vitek MP J Neurosci; 2007 Aug; 27(34):9155-68. PubMed ID: 17715352 [TBL] [Abstract][Full Text] [Related]
5. Correction of alternative splicing of tau in frontotemporal dementia and parkinsonism linked to chromosome 17. Kalbfuss B; Mabon SA; Misteli T J Biol Chem; 2001 Nov; 276(46):42986-93. PubMed ID: 11560926 [TBL] [Abstract][Full Text] [Related]
6. Tra2 beta, SF2/ASF and SRp30c modulate the function of an exonic splicing enhancer in exon 10 of tau pre-mRNA. Kondo S; Yamamoto N; Murakami T; Okumura M; Mayeda A; Imaizumi K Genes Cells; 2004 Feb; 9(2):121-30. PubMed ID: 15009090 [TBL] [Abstract][Full Text] [Related]
7. Chemical correction of pre-mRNA splicing defects associated with sequestration of muscleblind-like 1 protein by expanded r(CAG)-containing transcripts. Kumar A; Parkesh R; Sznajder LJ; Childs-Disney JL; Sobczak K; Disney MD ACS Chem Biol; 2012 Mar; 7(3):496-505. PubMed ID: 22252896 [TBL] [Abstract][Full Text] [Related]
8. Identification of small molecule inhibitors of pre-mRNA splicing. Pawellek A; McElroy S; Samatov T; Mitchell L; Woodland A; Ryder U; Gray D; Lührmann R; Lamond AI J Biol Chem; 2014 Dec; 289(50):34683-98. PubMed ID: 25281741 [TBL] [Abstract][Full Text] [Related]
9. Regulation of alternative splicing of tau exon 10. Qian W; Liu F Neurosci Bull; 2014 Apr; 30(2):367-77. PubMed ID: 24627328 [TBL] [Abstract][Full Text] [Related]
10. FTDP-17 mutations N279K and S305N in tau produce increased splicing of exon 10. Hasegawa M; Smith MJ; Iijima M; Tabira T; Goedert M FEBS Lett; 1999 Jan; 443(2):93-6. PubMed ID: 9989582 [TBL] [Abstract][Full Text] [Related]
11. Heterogeneous nuclear ribonucleoprotein E3 modestly activates splicing of tau exon 10 via its proximal downstream intron, a hotspot for frontotemporal dementia mutations. Wang Y; Gao L; Tse SW; Andreadis A Gene; 2010 Feb; 451(1-2):23-31. PubMed ID: 19914360 [TBL] [Abstract][Full Text] [Related]
12. Mutations in tau gene exon 10 associated with FTDP-17 alter the activity of an exonic splicing enhancer to interact with Tra2 beta. Jiang Z; Tang H; Havlioglu N; Zhang X; Stamm S; Yan R; Wu JY J Biol Chem; 2003 May; 278(21):18997-9007. PubMed ID: 12649279 [TBL] [Abstract][Full Text] [Related]
13. An SRp75/hnRNPG complex interacting with hnRNPE2 regulates the 5' splice site of tau exon 10, whose misregulation causes frontotemporal dementia. Wang Y; Wang J; Gao L; Stamm S; Andreadis A Gene; 2011 Oct; 485(2):130-8. PubMed ID: 21723381 [TBL] [Abstract][Full Text] [Related]
14. Rationally designed small molecules targeting the RNA that causes myotonic dystrophy type 1 are potently bioactive. Childs-Disney JL; Hoskins J; Rzuczek SG; Thornton CA; Disney MD ACS Chem Biol; 2012 May; 7(5):856-62. PubMed ID: 22332923 [TBL] [Abstract][Full Text] [Related]
15. A synthetic small molecule stalls pre-mRNA splicing by promoting an early-stage U2AF2-RNA complex. Chatrikhi R; Feeney CF; Pulvino MJ; Alachouzos G; MacRae AJ; Falls Z; Rai S; Brennessel WW; Jenkins JL; Walter MJ; Graubert TA; Samudrala R; Jurica MS; Frontier AJ; Kielkopf CL Cell Chem Biol; 2021 Aug; 28(8):1145-1157.e6. PubMed ID: 33689684 [TBL] [Abstract][Full Text] [Related]
17. Structural basis for recognition of the RNA major groove in the tau exon 10 splicing regulatory element by aminoglycoside antibiotics. Varani L; Spillantini MG; Goedert M; Varani G Nucleic Acids Res; 2000 Feb; 28(3):710-9. PubMed ID: 10637322 [TBL] [Abstract][Full Text] [Related]
18. Correction of tau mis-splicing caused by FTDP-17 MAPT mutations by spliceosome-mediated RNA trans-splicing. Rodriguez-Martin T; Anthony K; Garcia-Blanco MA; Mansfield SG; Anderton BH; Gallo JM Hum Mol Genet; 2009 Sep; 18(17):3266-73. PubMed ID: 19498037 [TBL] [Abstract][Full Text] [Related]
19. Glycogen synthase kinase-3 plays a crucial role in tau exon 10 splicing and intranuclear distribution of SC35. Implications for Alzheimer's disease. Hernández F; Pérez M; Lucas JJ; Mata AM; Bhat R; Avila J J Biol Chem; 2004 Jan; 279(5):3801-6. PubMed ID: 14602710 [TBL] [Abstract][Full Text] [Related]
20. Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors. Wang J; Gao QS; Wang Y; Lafyatis R; Stamm S; Andreadis A J Neurochem; 2004 Mar; 88(5):1078-90. PubMed ID: 15009664 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]