BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

290 related articles for article (PubMed ID: 32385075)

  • 1. Chromatin Regulator CHD1 Remodels the Immunosuppressive Tumor Microenvironment in PTEN-Deficient Prostate Cancer.
    Zhao D; Cai L; Lu X; Liang X; Li J; Chen P; Ittmann M; Shang X; Jiang S; Li H; Meng C; Flores I; Song JH; Horner JW; Lan Z; Wu CJ; Li J; Chang Q; Chen KC; Wang G; Deng P; Spring DJ; Wang YA; DePinho RA
    Cancer Discov; 2020 Sep; 10(9):1374-1387. PubMed ID: 32385075
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Organ-specific regulation of CHD1 by acute PTEN and p53 loss in mice.
    Rahmy S; Cheng X; Wang M; Feng H; Qiu W; Zhao R; Lu X
    Biochem Biophys Res Commun; 2020 May; 525(3):614-619. PubMed ID: 32115152
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthetic essentiality of chromatin remodelling factor CHD1 in PTEN-deficient cancer.
    Zhao D; Lu X; Wang G; Lan Z; Liao W; Li J; Liang X; Chen JR; Shah S; Shang X; Tang M; Deng P; Dey P; Chakravarti D; Chen P; Spring DJ; Navone NM; Troncoso P; Zhang J; Wang YA; DePinho RA
    Nature; 2017 Feb; 542(7642):484-488. PubMed ID: 28166537
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SPOP and CHD1 alterations in prostate cancer: Relationship with PTEN loss, tumor grade, perineural infiltration, and PSA recurrence.
    Hernández-Llodrà S; Segalés L; Juanpere N; Marta Lorenzo T; Salido M; Nonell L; David López T; Rodríguez-Vida A; Bellmunt J; Fumadó L; Cecchini L; Lloreta-Trull J
    Prostate; 2021 Dec; 81(16):1267-1277. PubMed ID: 34533858
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression.
    Wang G; Lu X; Dey P; Deng P; Wu CC; Jiang S; Fang Z; Zhao K; Konaparthi R; Hua S; Zhang J; Li-Ning-Tapia EM; Kapoor A; Wu CJ; Patel NB; Guo Z; Ramamoorthy V; Tieu TN; Heffernan T; Zhao D; Shang X; Khadka S; Hou P; Hu B; Jin EJ; Yao W; Pan X; Ding Z; Shi Y; Li L; Chang Q; Troncoso P; Logothetis CJ; McArthur MJ; Chin L; Wang YA; DePinho RA
    Cancer Discov; 2016 Jan; 6(1):80-95. PubMed ID: 26701088
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis.
    Augello MA; Liu D; Deonarine LD; Robinson BD; Huang D; Stelloo S; Blattner M; Doane AS; Wong EWP; Chen Y; Rubin MA; Beltran H; Elemento O; Bergman AM; Zwart W; Sboner A; Dephoure N; Barbieri CE
    Cancer Cell; 2019 Apr; 35(4):603-617.e8. PubMed ID: 30930119
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PTEN-deficient prostate cancer is associated with an immunosuppressive tumor microenvironment mediated by increased expression of IDO1 and infiltrating FoxP3+ T regulatory cells.
    Vidotto T; Saggioro FP; Jamaspishvili T; Chesca DL; Picanço de Albuquerque CG; Reis RB; Graham CH; Berman DM; Siemens DR; Squire JA; Koti M
    Prostate; 2019 Jun; 79(9):969-979. PubMed ID: 30999388
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression.
    Ding Z; Wu CJ; Chu GC; Xiao Y; Ho D; Zhang J; Perry SR; Labrot ES; Wu X; Lis R; Hoshida Y; Hiller D; Hu B; Jiang S; Zheng H; Stegh AH; Scott KL; Signoretti S; Bardeesy N; Wang YA; Hill DE; Golub TR; Stampfer MJ; Wong WH; Loda M; Mucci L; Chin L; DePinho RA
    Nature; 2011 Feb; 470(7333):269-73. PubMed ID: 21289624
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pten null prostate epithelium promotes localized myeloid-derived suppressor cell expansion and immune suppression during tumor initiation and progression.
    Garcia AJ; Ruscetti M; Arenzana TL; Tran LM; Bianci-Frias D; Sybert E; Priceman SJ; Wu L; Nelson PS; Smale ST; Wu H
    Mol Cell Biol; 2014 Jun; 34(11):2017-28. PubMed ID: 24662052
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Anti-androgen therapy induces transcriptomic reprogramming in metastatic castration-resistant prostate cancer in a murine model.
    Zhao Y; Peng X; Baldwin H; Zhang C; Liu Z; Lu X
    Biochim Biophys Acta Mol Basis Dis; 2021 Jul; 1867(7):166151. PubMed ID: 33892077
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reactivation of the tumor suppressor PTEN by mRNA nanoparticles enhances antitumor immunity in preclinical models.
    Lin YX; Wang Y; Ding J; Jiang A; Wang J; Yu M; Blake S; Liu S; Bieberich CJ; Farokhzad OC; Mei L; Wang H; Shi J
    Sci Transl Med; 2021 Jun; 13(599):. PubMed ID: 34162754
    [TBL] [Abstract][Full Text] [Related]  

  • 12. COUP-TFII inhibits TGF-β-induced growth barrier to promote prostate tumorigenesis.
    Qin J; Wu SP; Creighton CJ; Dai F; Xie X; Cheng CM; Frolov A; Ayala G; Lin X; Feng XH; Ittmann MM; Tsai SJ; Tsai MJ; Tsai SY
    Nature; 2013 Jan; 493(7431):236-40. PubMed ID: 23201680
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CHD1 Promotes Sensitivity to Aurora Kinase Inhibitors by Suppressing Interaction of AURKA with Its Coactivator TPX2.
    Li H; Wang Y; Lin K; Venkadakrishnan VB; Bakht M; Shi W; Meng C; Zhang J; Tremble K; Liang X; Song JH; Feng X; Van V; Deng P; Burks JK; Aparicio A; Keyomarsi K; Chen J; Lu Y; Beltran H; Zhao D
    Cancer Res; 2022 Sep; 82(17):3088-3101. PubMed ID: 35771632
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CHD1 is a 5q21 tumor suppressor required for ERG rearrangement in prostate cancer.
    Burkhardt L; Fuchs S; Krohn A; Masser S; Mader M; Kluth M; Bachmann F; Huland H; Steuber T; Graefen M; Schlomm T; Minner S; Sauter G; Sirma H; Simon R
    Cancer Res; 2013 May; 73(9):2795-805. PubMed ID: 23492366
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of novel CHD1-associated collaborative alterations of genomic structure and functional assessment of CHD1 in prostate cancer.
    Liu W; Lindberg J; Sui G; Luo J; Egevad L; Li T; Xie C; Wan M; Kim ST; Wang Z; Turner AR; Zhang Z; Feng J; Yan Y; Sun J; Bova GS; Ewing CM; Yan G; Gielzak M; Cramer SD; Vessella RL; Zheng SL; Grönberg H; Isaacs WB; Xu J
    Oncogene; 2012 Aug; 31(35):3939-48. PubMed ID: 22139082
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Immune checkpoint B7-H3 is a therapeutic vulnerability in prostate cancer harboring PTEN and TP53 deficiencies.
    Shi W; Wang Y; Zhao Y; Kim JJ; Li H; Meng C; Chen F; Zhang J; Mak DH; Van V; Leo J; St Croix B; Aparicio A; Zhao D
    Sci Transl Med; 2023 May; 15(695):eadf6724. PubMed ID: 37163614
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Efficacy of targeted AKT inhibition in genetically engineered mouse models of PTEN-deficient prostate cancer.
    De Velasco MA; Kura Y; Yoshikawa K; Nishio K; Davies BR; Uemura H
    Oncotarget; 2016 Mar; 7(13):15959-76. PubMed ID: 26910118
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NFATc1 promotes prostate tumorigenesis and overcomes PTEN loss-induced senescence.
    Manda KR; Tripathi P; Hsi AC; Ning J; Ruzinova MB; Liapis H; Bailey M; Zhang H; Maher CA; Humphrey PA; Andriole GL; Ding L; You Z; Chen F
    Oncogene; 2016 Jun; 35(25):3282-92. PubMed ID: 26477312
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Overcoming resistance to immune checkpoint therapy in PTEN-null prostate cancer by intermittent anti-PI3Kα/β/δ treatment.
    Qi Z; Xu Z; Zhang L; Zou Y; Li J; Yan W; Li C; Liu N; Wu H
    Nat Commun; 2022 Jan; 13(1):182. PubMed ID: 35013322
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TLR9-Targeted STAT3 Silencing Abrogates Immunosuppressive Activity of Myeloid-Derived Suppressor Cells from Prostate Cancer Patients.
    Hossain DM; Pal SK; Moreira D; Duttagupta P; Zhang Q; Won H; Jones J; D'Apuzzo M; Forman S; Kortylewski M
    Clin Cancer Res; 2015 Aug; 21(16):3771-82. PubMed ID: 25967142
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.