BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

192 related articles for article (PubMed ID: 32388428)

  • 1. Novel formyl peptide receptor (FPR) agonists with pyridinone and pyrimidindione scaffolds that are potentially useful for the treatment of rheumatoid arthritis.
    Crocetti L; Vergelli C; Guerrini G; Cantini N; Kirpotina LN; Schepetkin IA; Quinn MT; Parisio C; Di Cesare Mannelli L; Ghelardini C; Giovannoni MP
    Bioorg Chem; 2020 Jul; 100():103880. PubMed ID: 32388428
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pyridinone Derivatives as Interesting Formyl Peptide Receptor (FPR) Agonists for the Treatment of Rheumatoid Arthritis.
    Crocetti L; Vergelli C; Guerrini G; Giovannoni MP; Kirpotina LN; Khlebnikov AI; Ghelardini C; Di Cesare Mannelli L; Lucarini E; Schepetkin IA; Quinn MT
    Molecules; 2021 Oct; 26(21):. PubMed ID: 34770992
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis, biological evaluation, molecular modeling, and structural analysis of new pyrazole and pyrazolone derivatives as N-formyl peptide receptors agonists.
    Vergelli C; Khlebnikov AI; Crocetti L; Guerrini G; Cantini N; Kirpotina LN; Schepetkin IA; Cilibrizzi A; Quinn MT; Rossi P; Paoli P; Giovannoni MP
    Chem Biol Drug Des; 2021 Oct; 98(4):582-603. PubMed ID: 34148303
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of Five- and Six-Membered N-Phenylacetamido Substituted Heterocycles as Formyl Peptide Receptor Agonists.
    Vergelli C; Schepetkin IA; Ciciani G; Cilibrizzi A; Crocetti L; Giovannoni MP; Guerrini G; Iacovone A; Kirpotina LN; Ye RD; Quinn MT
    Drug Dev Res; 2017 Feb; 78(1):49-62. PubMed ID: 27859446
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Further studies on 2-arylacetamide pyridazin-3(2H)-ones: design, synthesis and evaluation of 4,6-disubstituted analogs as formyl peptide receptors (FPRs) agonists.
    Giovannoni MP; Schepetkin IA; Cilibrizzi A; Crocetti L; Khlebnikov AI; Dahlgren C; Graziano A; Dal Piaz V; Kirpotina LN; Zerbinati S; Vergelli C; Quinn MT
    Eur J Med Chem; 2013 Jun; 64():512-28. PubMed ID: 23685570
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 2-Arylacetamido-4-phenylamino-5-substituted pyridazinones as formyl peptide receptors agonists.
    Vergelli C; Schepetkin IA; Ciciani G; Cilibrizzi A; Crocetti L; Giovannoni MP; Guerrini G; Iacovone A; Kirpotina LN; Khlebnikov AI; Ye RD; Quinn MT
    Bioorg Med Chem; 2016 Jun; 24(11):2530-2543. PubMed ID: 27134116
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Gastrin-releasing peptide/neuromedin B receptor antagonists PD176252, PD168368, and related analogs are potent agonists of human formyl-peptide receptors.
    Schepetkin IA; Kirpotina LN; Khlebnikov AI; Jutila MA; Quinn MT
    Mol Pharmacol; 2011 Jan; 79(1):77-90. PubMed ID: 20943772
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of novel small-molecule agonists for human formyl peptide receptors and pharmacophore models of their recognition.
    Kirpotina LN; Khlebnikov AI; Schepetkin IA; Ye RD; Rabiet MJ; Jutila MA; Quinn MT
    Mol Pharmacol; 2010 Feb; 77(2):159-70. PubMed ID: 19903830
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 3-(1H-indol-3-yl)-2-[3-(4-nitrophenyl)ureido]propanamide enantiomers with human formyl-peptide receptor agonist activity: molecular modeling of chiral recognition by FPR2.
    Schepetkin IA; Kirpotina LN; Khlebnikov AI; Leopoldo M; Lucente E; Lacivita E; De Giorgio P; Quinn MT
    Biochem Pharmacol; 2013 Feb; 85(3):404-16. PubMed ID: 23219934
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A non-peptide receptor inhibitor with selectivity for one of the neutrophil formyl peptide receptors, FPR 1.
    Cevik-Aras H; Kalderén C; Jenmalm Jensen A; Oprea T; Dahlgren C; Forsman H
    Biochem Pharmacol; 2012 Jun; 83(12):1655-62. PubMed ID: 22410002
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Formyl peptide receptor activation inhibits the expansion of effector T cells and synovial fibroblasts and attenuates joint injury in models of rheumatoid arthritis.
    Odobasic D; Jia Y; Kao W; Fan H; Wei X; Gu R; Ngo D; Kitching AR; Holdsworth SR; Morand EF; Yang YH
    Int Immunopharmacol; 2018 Aug; 61():140-149. PubMed ID: 29879657
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functional selective FPR1 signaling in favor of an activation of the neutrophil superoxide generating NOX2 complex.
    Lind S; Dahlgren C; Holmdahl R; Olofsson P; Forsman H
    J Leukoc Biol; 2021 Jun; 109(6):1105-1120. PubMed ID: 33040403
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A formyl peptide receptor agonist suppresses inflammation and bone damage in arthritis.
    Kao W; Gu R; Jia Y; Wei X; Fan H; Harris J; Zhang Z; Quinn J; Morand EF; Yang YH
    Br J Pharmacol; 2014 Sep; 171(17):4087-96. PubMed ID: 24824742
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Stable formyl peptide receptor agonists that activate the neutrophil NADPH-oxidase identified through screening of a compound library.
    Forsman H; Kalderén C; Nordin A; Nordling E; Jensen AJ; Dahlgren C
    Biochem Pharmacol; 2011 Feb; 81(3):402-11. PubMed ID: 21095183
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antagonism of human formyl peptide receptor 1 (FPR1) by chromones and related isoflavones.
    Schepetkin IA; Kirpotina LN; Khlebnikov AI; Cheng N; Ye RD; Quinn MT
    Biochem Pharmacol; 2014 Dec; 92(4):627-41. PubMed ID: 25450672
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The formyl peptide receptor 1 exerts a tumor suppressor function in human gastric cancer by inhibiting angiogenesis.
    Prevete N; Liotti F; Visciano C; Marone G; Melillo RM; de Paulis A
    Oncogene; 2015 Jul; 34(29):3826-38. PubMed ID: 25263443
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 4-Aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-ones as N-formyl peptide receptor 1 (FPR1) antagonists.
    Kirpotina LN; Schepetkin IA; Khlebnikov AI; Ruban OI; Ge Y; Ye RD; Kominsky DJ; Quinn MT
    Biochem Pharmacol; 2017 Oct; 142():120-132. PubMed ID: 28690139
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 6-methyl-2,4-disubstituted pyridazin-3(2H)-ones: a novel class of small-molecule agonists for formyl peptide receptors.
    Cilibrizzi A; Quinn MT; Kirpotina LN; Schepetkin IA; Holderness J; Ye RD; Rabiet MJ; Biancalani C; Cesari N; Graziano A; Vergelli C; Pieretti S; Dal Piaz V; Giovannoni MP
    J Med Chem; 2009 Aug; 52(16):5044-57. PubMed ID: 19639995
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The formyl peptide receptor agonist FPRa14 induces differentiation of Neuro2a mouse neuroblastoma cells into multiple distinct morphologies which can be specifically inhibited with FPR antagonists and FPR knockdown using siRNA.
    Cussell PJG; Howe MS; Illingworth TA; Gomez Escalada M; Milton NGN; Paterson AWJ
    PLoS One; 2019; 14(6):e0217815. PubMed ID: 31170199
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Functional and signaling characterization of the neutrophil FPR2 selective agonist Act-389949.
    Lind S; Sundqvist M; Holmdahl R; Dahlgren C; Forsman H; Olofsson P
    Biochem Pharmacol; 2019 Aug; 166():163-173. PubMed ID: 31085160
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.