BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 32393662)

  • 1. Therapeutic Targeting of the Secreted Lysophospholipase D Autotaxin Suppresses Tuberous Sclerosis Complex-Associated Tumorigenesis.
    Feng Y; Mischler WJ; Gurung AC; Kavanagh TR; Androsov G; Sadow PM; Herbert ZT; Priolo C
    Cancer Res; 2020 Jul; 80(13):2751-2763. PubMed ID: 32393662
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Urokinase-type plasminogen activator (uPA) is critical for progression of tuberous sclerosis complex 2 (TSC2)-deficient tumors.
    Stepanova V; Dergilev KV; Holman KR; Parfyonova YV; Tsokolaeva ZI; Teter M; Atochina-Vasserman EN; Volgina A; Zaitsev SV; Lewis SP; Zabozlaev FG; Obraztsova K; Krymskaya VP; Cines DB
    J Biol Chem; 2017 Dec; 292(50):20528-20543. PubMed ID: 28972182
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rapamycin-insensitive up-regulation of adipocyte phospholipase A2 in tuberous sclerosis and lymphangioleiomyomatosis.
    Li C; Zhang E; Sun Y; Lee PS; Zhan Y; Guo Y; Osorio JC; Rosas IO; Xu KF; Kwiatkowski DJ; Yu JJ
    PLoS One; 2014; 9(10):e104809. PubMed ID: 25347447
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tuberin regulates E-cadherin localization: implications in epithelial-mesenchymal transition.
    Barnes EA; Kenerson HL; Jiang X; Yeung RS
    Am J Pathol; 2010 Oct; 177(4):1765-78. PubMed ID: 20813961
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Renal disease in tuberous sclerosis complex: pathogenesis and therapy.
    Lam HC; Siroky BJ; Henske EP
    Nat Rev Nephrol; 2018 Nov; 14(11):704-716. PubMed ID: 30232410
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Vps34-mediated macropinocytosis in Tuberous Sclerosis Complex 2-deficient cells supports tumorigenesis.
    Filippakis H; Belaid A; Siroky B; Wu C; Alesi N; Hougard T; Nijmeh J; Lam HC; Henske EP
    Sci Rep; 2018 Sep; 8(1):14161. PubMed ID: 30242175
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Therapeutic Targeting of DGKA-Mediated Macropinocytosis Leads to Phospholipid Reprogramming in Tuberous Sclerosis Complex.
    Kovalenko A; Sanin A; Kosmas K; Zhang L; Wang J; Akl EW; Giannikou K; Probst CK; Hougard TR; Rue RW; Krymskaya VP; Asara JM; Lam HC; Kwiatkowski DJ; Henske EP; Filippakis H
    Cancer Res; 2021 Apr; 81(8):2086-2100. PubMed ID: 33593821
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rapamycin-upregulated miR-29b promotes mTORC1-hyperactive cell growth in TSC2-deficient cells by downregulating tumor suppressor retinoic acid receptor β (RARβ).
    Liu HJ; Lam HC; Baglini CV; Nijmeh J; Cottrill AA; Chan SY; Henske EP
    Oncogene; 2019 Dec; 38(49):7367-7383. PubMed ID: 31420607
    [TBL] [Abstract][Full Text] [Related]  

  • 9. mTORC1 enhancement of STIM1-mediated store-operated Ca2+ entry constrains tuberous sclerosis complex-related tumor development.
    Peng H; Liu J; Sun Q; Chen R; Wang Y; Duan J; Li C; Li B; Jing Y; Chen X; Mao Q; Xu KF; Walker CL; Li J; Wang J; Zhang H
    Oncogene; 2013 Sep; 32(39):4702-11. PubMed ID: 23108404
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TSC2 Interacts with HDLBP/Vigilin and Regulates Stress Granule Formation.
    Kosmas K; Filippakis H; Khabibullin D; Turkiewicz M; Lam HC; Yu J; Kedersha NL; Anderson PJ; Henske EP
    Mol Cancer Res; 2021 Aug; 19(8):1389-1397. PubMed ID: 33888601
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tyrosine Kinase Inhibitors Diminish Renal Neoplasms in a Tuberous Sclerosis Model Via Induction of Apoptosis.
    Unachukwu U; Sonett J; Woode D; Shiomi T; Chada K; D'Armiento JM
    Mol Cancer Ther; 2023 Jul; 22(7):844-858. PubMed ID: 37127876
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TSC2-deficient tumors have evidence of T cell exhaustion and respond to anti-PD-1/anti-CTLA-4 immunotherapy.
    Liu HJ; Lizotte PH; Du H; Speranza MC; Lam HC; Vaughan S; Alesi N; Wong KK; Freeman GJ; Sharpe AH; Henske EP
    JCI Insight; 2018 Apr; 3(8):. PubMed ID: 29669930
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Upregulation of 6-phosphofructo-2-kinase (PFKFB3) by hyperactivated mammalian target of rapamycin complex 1 is critical for tumor growth in tuberous sclerosis complex.
    Wang Y; Tang S; Wu Y; Wan X; Zhou M; Li H; Zha X
    IUBMB Life; 2020 May; 72(5):965-977. PubMed ID: 31958214
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Signaling events downstream of mammalian target of rapamycin complex 2 are attenuated in cells and tumors deficient for the tuberous sclerosis complex tumor suppressors.
    Huang J; Wu S; Wu CL; Manning BD
    Cancer Res; 2009 Aug; 69(15):6107-14. PubMed ID: 19602587
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tuberous sclerosis complex and DNA repair.
    Habib SL
    Adv Exp Med Biol; 2010; 685():84-94. PubMed ID: 20687497
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tuberin Regulates Prostaglandin Receptor-Mediated Viability, via Rheb, in mTORC1-Hyperactive Cells.
    Li C; Liu X; Liu Y; Zhang E; Medepalli K; Masuda K; Li N; Wikenheiser-Brokamp KA; Osterburg A; Borchers MT; Kopras EJ; Plas DR; Sun J; Franz DN; Capal JK; Mays M; Sun Y; Kwiatkowski DJ; Alayev A; Holz MK; Krueger DA; Siroky BJ; Yu JJ
    Mol Cancer Res; 2017 Oct; 15(10):1318-1330. PubMed ID: 28710231
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Real-time monitoring of tumorigenesis, dissemination, & drug response in a preclinical model of lymphangioleiomyomatosis/tuberous sclerosis complex.
    Liu F; Lunsford EP; Tong J; Ashitate Y; Gibbs SL; Yu J; Choi HS; Henske EP; Frangioni JV
    PLoS One; 2012; 7(6):e38589. PubMed ID: 22719903
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Autophagy: an 'Achilles' heel of tumorigenesis in TSC and LAM.
    Yu J; Parkhitko A; Henske EP
    Autophagy; 2011 Nov; 7(11):1400-1. PubMed ID: 21997371
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development.
    Giannikou K; Malinowska IA; Pugh TJ; Yan R; Tseng YY; Oh C; Kim J; Tyburczy ME; Chekaluk Y; Liu Y; Alesi N; Finlay GA; Wu CL; Signoretti S; Meyerson M; Getz G; Boehm JS; Henske EP; Kwiatkowski DJ
    PLoS Genet; 2016 Aug; 12(8):e1006242. PubMed ID: 27494029
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Renal disease in adults with TSC2/PKD1 contiguous gene syndrome.
    Martignoni G; Bonetti F; Pea M; Tardanico R; Brunelli M; Eble JN
    Am J Surg Pathol; 2002 Feb; 26(2):198-205. PubMed ID: 11812941
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.