These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

116 related articles for article (PubMed ID: 32402249)

  • 1. Flanking Regions Determine the Structure of the Poly-Glutamine in Huntingtin through Mechanisms Common among Glutamine-Rich Human Proteins.
    Urbanek A; Popovic M; Morató A; Estaña A; Elena-Real CA; Mier P; Fournet A; Allemand F; Delbecq S; Andrade-Navarro MA; Cortés J; Sibille N; Bernadó P
    Structure; 2020 Jul; 28(7):733-746.e5. PubMed ID: 32402249
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The structure of pathogenic huntingtin exon 1 defines the bases of its aggregation propensity.
    Elena-Real CA; Sagar A; Urbanek A; Popovic M; Morató A; Estaña A; Fournet A; Doucet C; Lund XL; Shi ZD; Costa L; Thureau A; Allemand F; Swenson RE; Milhiet PE; Crehuet R; Barducci A; Cortés J; Sinnaeve D; Sibille N; Bernadó P
    Nat Struct Mol Biol; 2023 Mar; 30(3):309-320. PubMed ID: 36864173
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The folding equilibrium of huntingtin exon 1 monomer depends on its polyglutamine tract.
    Bravo-Arredondo JM; Kegulian NC; Schmidt T; Pandey NK; Situ AJ; Ulmer TS; Langen R
    J Biol Chem; 2018 Dec; 293(51):19613-19623. PubMed ID: 30315108
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The 17-residue-long N terminus in huntingtin controls stepwise aggregation in solution and on membranes via different mechanisms.
    Pandey NK; Isas JM; Rawat A; Lee RV; Langen J; Pandey P; Langen R
    J Biol Chem; 2018 Feb; 293(7):2597-2605. PubMed ID: 29282287
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An Expanded Polyproline Domain Maintains Mutant Huntingtin Soluble
    Pigazzini ML; Lawrenz M; Margineanu A; Kaminski Schierle GS; Kirstein J
    Front Mol Neurosci; 2021; 14():721749. PubMed ID: 34720872
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dynamics of the Proline-Rich C-Terminus of Huntingtin Exon-1 Fibrils.
    Caulkins BG; Cervantes SA; Isas JM; Siemer AB
    J Phys Chem B; 2018 Oct; 122(41):9507-9515. PubMed ID: 30252478
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Multi-site-specific isotopic labeling accelerates high-resolution structural investigations of pathogenic huntingtin exon-1.
    Elena-Real CA; Urbanek A; Lund XL; Morató A; Sagar A; Fournet A; Estaña A; Bellande T; Allemand F; Cortés J; Sibille N; Melki R; Bernadó P
    Structure; 2023 Jun; 31(6):644-650.e5. PubMed ID: 37119819
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glassy dynamics in mutant huntingtin proteins.
    Kang H; Luan B; Zhou R
    J Chem Phys; 2018 Aug; 149(7):072333. PubMed ID: 30134683
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Flanking polyproline sequences inhibit beta-sheet structure in polyglutamine segments by inducing PPII-like helix structure.
    Darnell G; Orgel JP; Pahl R; Meredith SC
    J Mol Biol; 2007 Nov; 374(3):688-704. PubMed ID: 17945257
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Is there codon usage bias for poly-Q stretches in the human proteome?
    Galzitskaya OV; Novikov GS; Dovidchenko NV; Lobanov MY
    J Bioinform Comput Biol; 2019 Feb; 17(1):1950010. PubMed ID: 30866735
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural insights into the aggregation mechanism of huntingtin exon 1 protein fragment with different polyQ-lengths.
    Priya SB; Gromiha MM
    J Cell Biochem; 2019 Jun; 120(6):10519-10529. PubMed ID: 30672003
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure and Dynamics of the Huntingtin Exon-1 N-Terminus: A Solution NMR Perspective.
    Baias M; Smith PE; Shen K; Joachimiak LA; Żerko S; Koźmiński W; Frydman J; Frydman L
    J Am Chem Soc; 2017 Jan; 139(3):1168-1176. PubMed ID: 28085263
    [TBL] [Abstract][Full Text] [Related]  

  • 13. When Less Is More: Combining Site-Specific Isotope Labeling and NMR Unravels Structural Details of Huntingtin Repeats.
    Delhommel F; Sattler M
    Structure; 2020 Jul; 28(7):730-732. PubMed ID: 32640252
    [TBL] [Abstract][Full Text] [Related]  

  • 14. N-terminal Huntingtin (Htt) phosphorylation is a molecular switch regulating Htt aggregation, helical conformation, internalization, and nuclear targeting.
    DeGuire SM; Ruggeri FS; Fares MB; Chiki A; Cendrowska U; Dietler G; Lashuel HA
    J Biol Chem; 2018 Nov; 293(48):18540-18558. PubMed ID: 30185623
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis of pathological and nonpathological human exon 1 huntingtin.
    Singer D; Zauner T; Genz M; Hoffmann R; Zuchner T
    J Pept Sci; 2010 Jul; 16(7):358-63. PubMed ID: 20552561
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Modeling protein homopolymeric repeats: possible polyglutamine structural motifs for Huntington's disease.
    Lathrop RH; Casale M; Tobias DJ; Marsh JL; Thompson LM
    Proc Int Conf Intell Syst Mol Biol; 1998; 6():105-14. PubMed ID: 9783215
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Atomistic mechanisms of huntingtin N-terminal fragment insertion on a phospholipid bilayer revealed by molecular dynamics simulations.
    Côté S; Wei G; Mousseau N
    Proteins; 2014 Jul; 82(7):1409-27. PubMed ID: 24415136
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protofilament Structure and Supramolecular Polymorphism of Aggregated Mutant Huntingtin Exon 1.
    Boatz JC; Piretra T; Lasorsa A; Matlahov I; Conway JF; van der Wel PCA
    J Mol Biol; 2020 Jul; 432(16):4722-4744. PubMed ID: 32598938
    [TBL] [Abstract][Full Text] [Related]  

  • 19. All-atom stability and oligomerization simulations of polyglutamine nanotubes with and without the 17-amino-acid N-terminal fragment of the Huntingtin protein.
    Côté S; Wei G; Mousseau N
    J Phys Chem B; 2012 Oct; 116(40):12168-79. PubMed ID: 22978784
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Conformational dynamics and self-association of intrinsically disordered Huntingtin exon 1 in cells.
    Büning S; Sharma A; Vachharajani S; Newcombe E; Ormsby A; Gao M; Gnutt D; Vöpel T; Hatters DM; Ebbinghaus S
    Phys Chem Chem Phys; 2017 May; 19(17):10738-10747. PubMed ID: 28094373
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.