BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

256 related articles for article (PubMed ID: 32405891)

  • 1. Hemocompatible LAT1-inhibitor can induce apoptosis in cancer cells without affecting brain amino acid homeostasis.
    Markowicz-Piasecka M; Huttunen J; Montaser A; Huttunen KM
    Apoptosis; 2020 Jun; 25(5-6):426-440. PubMed ID: 32405891
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metformin enhances anti-tumor effect of L-type amino acid transporter 1 (LAT1) inhibitor.
    Ueno S; Kimura T; Yamaga T; Kawada A; Ochiai T; Endou H; Sakurai H
    J Pharmacol Sci; 2016 Jun; 131(2):110-7. PubMed ID: 27262901
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of the amino-acid transporter LAT1 demonstrates anti-neoplastic activity in medulloblastoma.
    Cormerais Y; Pagnuzzi-Boncompagni M; Schrötter S; Giuliano S; Tambutté E; Endou H; Wempe MF; Pagès G; Pouysségur J; Picco V
    J Cell Mol Med; 2019 Apr; 23(4):2711-2718. PubMed ID: 30784173
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Selective and Slowly Reversible Inhibitor of l-Type Amino Acid Transporter 1 (LAT1) Potentiates Antiproliferative Drug Efficacy in Cancer Cells.
    Huttunen KM; Gynther M; Huttunen J; Puris E; Spicer JA; Denny WA
    J Med Chem; 2016 Jun; 59(12):5740-51. PubMed ID: 27253989
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hemocompatible L-Type amino acid transporter 1 (LAT1)-Utilizing prodrugs of perforin inhibitors can accumulate into the pancreas and alleviate inflammation-induced apoptosis.
    Tampio J; Markowicz-Piasecka M; Huttunen KM
    Chem Biol Interact; 2021 Aug; 345():109560. PubMed ID: 34153225
    [TBL] [Abstract][Full Text] [Related]  

  • 6. L-Type Amino Acid Transporter 1 Regulates Cancer Stemness and the Expression of Programmed Cell Death 1 Ligand 1 in Lung Cancer Cells.
    Liu YH; Li YL; Shen HT; Chien PJ; Sheu GT; Wang BY; Chang WW
    Int J Mol Sci; 2021 Oct; 22(20):. PubMed ID: 34681614
    [TBL] [Abstract][Full Text] [Related]  

  • 7. L-type amino acid transporter 1 (LAT1)-utilizing efflux transporter inhibitors can improve the brain uptake and apoptosis-inducing effects of vinblastine in cancer cells.
    Montaser A; Markowicz-Piasecka M; Sikora J; Jalkanen A; Huttunen KM
    Int J Pharm; 2020 Aug; 586():119585. PubMed ID: 32599132
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-activity relations of leucine derivatives reveal critical moieties for cellular uptake and activation of mTORC1-mediated signaling.
    Nagamori S; Wiriyasermkul P; Okuda S; Kojima N; Hari Y; Kiyonaka S; Mori Y; Tominaga H; Ohgaki R; Kanai Y
    Amino Acids; 2016 Apr; 48(4):1045-1058. PubMed ID: 26724922
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Expression of L-type amino acid transporter 1 as a molecular target for prognostic and therapeutic indicators in bladder carcinoma.
    Maimaiti M; Sakamoto S; Yamada Y; Sugiura M; Rii J; Takeuchi N; Imamura Y; Furihata T; Ando K; Higuchi K; Xu M; Sazuka T; Nakamura K; Kaneda A; Kanai Y; Kyprianou N; Ikehara Y; Anzai N; Ichikawa T
    Sci Rep; 2020 Jan; 10(1):1292. PubMed ID: 31992742
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-activity relationship of a novel series of inhibitors for cancer type transporter L-type amino acid transporter 1 (LAT1).
    Kongpracha P; Nagamori S; Wiriyasermkul P; Tanaka Y; Kaneda K; Okuda S; Ohgaki R; Kanai Y
    J Pharmacol Sci; 2017 Feb; 133(2):96-102. PubMed ID: 28242177
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel therapeutic approach for anaplastic thyroid cancer through inhibition of LAT1.
    Enomoto K; Sato F; Tamagawa S; Gunduz M; Onoda N; Uchino S; Muragaki Y; Hotomi M
    Sci Rep; 2019 Oct; 9(1):14616. PubMed ID: 31601917
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Aryl hydrocarbon receptor (AHR) regulation of L-Type Amino Acid Transporter 1 (LAT-1) expression in MCF-7 and MDA-MB-231 breast cancer cells.
    Tomblin JK; Arthur S; Primerano DA; Chaudhry AR; Fan J; Denvir J; Salisbury TB
    Biochem Pharmacol; 2016 Apr; 106():94-103. PubMed ID: 26944194
    [TBL] [Abstract][Full Text] [Related]  

  • 13. JPH203, an L-type amino acid transporter 1-selective compound, induces apoptosis of YD-38 human oral cancer cells.
    Yun DW; Lee SA; Park MG; Kim JS; Yu SK; Park MR; Kim SG; Oh JS; Kim CS; Kim HJ; Kim JS; Chun HS; Kanai Y; Endou H; Wempe MF; Kim DK
    J Pharmacol Sci; 2014; 124(2):208-17. PubMed ID: 24492461
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Different Response Profiles of Gastrointestinal Cancer Cells to an L-Type Amino Acid Transporter Inhibitor, JPH203.
    Muto Y; Furihata T; Kaneko M; Higuchi K; Okunushi K; Morio H; Reien Y; Uesato M; Matsubara H; Anzai N
    Anticancer Res; 2019 Jan; 39(1):159-165. PubMed ID: 30591453
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MicroRNA-126-3p Inhibits Angiogenic Function of Human Lung Microvascular Endothelial Cells via LAT1 (L-Type Amino Acid Transporter 1)-Mediated mTOR (Mammalian Target of Rapamycin) Signaling.
    Cao D; Mikosz AM; Ringsby AJ; Anderson KC; Beatman EL; Koike K; Petrache I
    Arterioscler Thromb Vasc Biol; 2020 May; 40(5):1195-1206. PubMed ID: 32212853
    [TBL] [Abstract][Full Text] [Related]  

  • 16. LAT1 acts as a crucial transporter of amino acids in human thymic carcinoma cells.
    Hayashi K; Jutabha P; Maeda S; Supak Y; Ouchi M; Endou H; Fujita T; Chida M; Anzai N
    J Pharmacol Sci; 2016 Nov; 132(3):201-204. PubMed ID: 27567475
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation.
    Quan L; Ohgaki R; Hara S; Okuda S; Wei L; Okanishi H; Nagamori S; Endou H; Kanai Y
    J Exp Clin Cancer Res; 2020 Nov; 39(1):266. PubMed ID: 33256804
    [TBL] [Abstract][Full Text] [Related]  

  • 18. JPH203, a newly developed anti-cancer drug, shows a preincubation inhibitory effect on L-type amino acid transporter 1 function.
    Okunushi K; Furihata T; Morio H; Muto Y; Higuchi K; Kaneko M; Otsuka Y; Ohno Y; Watanabe Y; Reien Y; Nakagawa K; Sakamoto S; Wakashin H; Shimojo N; Anzai N
    J Pharmacol Sci; 2020 Sep; 144(1):16-22. PubMed ID: 32653341
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Platelet-derived growth factor stimulates LAT1 gene expression in vascular smooth muscle: role in cell growth.
    Liu XM; Reyna SV; Ensenat D; Peyton KJ; Wang H; Schafer AI; Durante W
    FASEB J; 2004 Apr; 18(6):768-70. PubMed ID: 14977877
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The LAT1 inhibitor JPH203 reduces growth of thyroid carcinoma in a fully immunocompetent mouse model.
    Häfliger P; Graff J; Rubin M; Stooss A; Dettmer MS; Altmann KH; Gertsch J; Charles RP
    J Exp Clin Cancer Res; 2018 Sep; 37(1):234. PubMed ID: 30241549
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.