231 related articles for article (PubMed ID: 32407621)
1. Glycan-Mediated Technology for Obtaining Homogeneous Site-Specific Conjugated Antibody-Drug Conjugates: Synthesis and Analytical Characterization by Using Complementary Middle-up LC/HRMS Analysis.
Duivelshof BL; Deslignière E; Hernandez-Alba O; Ehkirch A; Toftevall H; Sjögren J; Cianferani S; Beck A; Guillarme D; D'Atri V
Anal Chem; 2020 Jun; 92(12):8170-8177. PubMed ID: 32407621
[TBL] [Abstract][Full Text] [Related]
2. Characterization of an antibody-drug conjugate by hydrophilic interaction chromatography coupled to mass spectrometry.
D'Atri V; Fekete S; Stoll D; Lauber M; Beck A; Guillarme D
J Chromatogr B Analyt Technol Biomed Life Sci; 2018 Mar; 1080():37-41. PubMed ID: 29477065
[TBL] [Abstract][Full Text] [Related]
3. Two-Dimensional Liquid Chromatography Coupled to High-Resolution Mass Spectrometry for the Analysis of ADCs.
Chapel S; Rouvière F; Sarrut M; Heinisch S
Methods Mol Biol; 2020; 2078():163-185. PubMed ID: 31643056
[TBL] [Abstract][Full Text] [Related]
4. A Combination of Native LC-MS Approaches for the Comprehensive Characterization of the Antibody-Drug Conjugate Trastuzumab Deruxtecan.
Deslignière E; Diemer H; Erb S; Coliat P; Pivot X; Detappe A; Hernandez-Alba O; Cianférani S
Front Biosci (Landmark Ed); 2022 Oct; 27(10):290. PubMed ID: 36336868
[TBL] [Abstract][Full Text] [Related]
5. Practical approaches for overcoming challenges in heightened characterization of antibody-drug conjugates with new methodologies and ultrahigh-resolution mass spectrometry.
Friese OV; Smith JN; Brown PW; Rouse JC
MAbs; 2018 Apr; 10(3):335-345. PubMed ID: 29393747
[TBL] [Abstract][Full Text] [Related]
6. [The Characterization of Drug-to-Antibody Ratio and Isoforms of ADCs Using LC and MS Technologies].
Iizuka R; Kotch F; Xu A; Porter T; Shion H; Birdsall R; Chen W
Yakugaku Zasshi; 2017; 137(5):525-528. PubMed ID: 28458283
[TBL] [Abstract][Full Text] [Related]
7. A rapid on-line method for mass spectrometric confirmation of a cysteine-conjugated antibody-drug-conjugate structure using multidimensional chromatography.
Birdsall RE; Shion H; Kotch FW; Xu A; Porter TJ; Chen W
MAbs; 2015; 7(6):1036-44. PubMed ID: 26305867
[TBL] [Abstract][Full Text] [Related]
8. Accurate determination of drug-to-antibody ratio of interchain cysteine-linked antibody-drug conjugates by LC-HRMS.
Li K; Zhang Z; Lin ZJ; Shi H; Ma Y
Anal Bioanal Chem; 2020 Feb; 412(4):833-840. PubMed ID: 31872274
[TBL] [Abstract][Full Text] [Related]
9. Conjugation site analysis of antibody-drug-conjugates (ADCs) by signature ion fingerprinting and normalized area quantitation approach using nano-liquid chromatography coupled to high resolution mass spectrometry.
Sang H; Lu G; Liu Y; Hu Q; Xing W; Cui D; Zhou F; Zhang J; Hao H; Wang G; Ye H
Anal Chim Acta; 2017 Feb; 955():67-78. PubMed ID: 28088282
[TBL] [Abstract][Full Text] [Related]
10. Custom-Designed Affinity Capture LC-MS F(ab')2 Assay for Biotransformation Assessment of Site-Specific Antibody Drug Conjugates.
Su D; Ng C; Khosraviani M; Yu SF; Cosino E; Kaur S; Xu K
Anal Chem; 2016 Dec; 88(23):11340-11346. PubMed ID: 27779866
[TBL] [Abstract][Full Text] [Related]
11. A native SEC-MS workflow and validation for analyzing drug-to-antibody ratio and drug load distribution in cysteine-linked antibody-drug conjugates.
Wu G; Yu C; Yin S; Du J; Zhang Y; Fu Z; Wang L; Wang J
J Chromatogr B Analyt Technol Biomed Life Sci; 2024 Jul; 1241():124167. PubMed ID: 38823148
[TBL] [Abstract][Full Text] [Related]
12. State-of-the-Art Native Mass Spectrometry and Ion Mobility Methods to Monitor Homogeneous Site-Specific Antibody-Drug Conjugates Synthesis.
Deslignière E; Ehkirch A; Duivelshof BL; Toftevall H; Sjögren J; Guillarme D; D'Atri V; Beck A; Hernandez-Alba O; Cianférani S
Pharmaceuticals (Basel); 2021 May; 14(6):. PubMed ID: 34073805
[TBL] [Abstract][Full Text] [Related]
13. Innovative native MS methodologies for antibody drug conjugate characterization: High resolution native MS and IM-MS for average DAR and DAR distribution assessment.
Debaene F; Boeuf A; Wagner-Rousset E; Colas O; Ayoub D; Corvaïa N; Van Dorsselaer A; Beck A; Cianférani S
Anal Chem; 2014 Nov; 86(21):10674-83. PubMed ID: 25270580
[TBL] [Abstract][Full Text] [Related]
14. Determination of drug-to-antibody ratio of antibody-drug conjugate in biological samples using microflow-liquid chromatography/high-resolution mass spectrometry.
Inoue K; Mochizuki T; Kasamori N; Komori T
Bioanalysis; 2022 Dec; 14(24):1533-1545. PubMed ID: 36825963
[TBL] [Abstract][Full Text] [Related]
15. Rapid Analysis of Reduced Antibody Drug Conjugate by Online LC-MS/MS with Fourier Transform Ion Cyclotron Resonance Mass Spectrometry.
Larson EJ; Zhu Y; Wu Z; Chen B; Zhang Z; Zhou S; Han L; Zhang Q; Ge Y
Anal Chem; 2020 Nov; 92(22):15096-15103. PubMed ID: 33108180
[TBL] [Abstract][Full Text] [Related]
16. Middle-Down Multi-Attribute Analysis of Antibody-Drug Conjugates with Electron Transfer Dissociation.
Chen B; Lin Z; Zhu Y; Jin Y; Larson E; Xu Q; Fu C; Zhang Z; Zhang Q; Pritts WA; Ge Y
Anal Chem; 2019 Sep; 91(18):11661-11669. PubMed ID: 31442030
[TBL] [Abstract][Full Text] [Related]
17. Site-specific glycan-conjugated NISTmAb antibody drug conjugate mimetics: synthesis, characterization, and utility.
Agnew B; Lin S; Zhang T; Aggeler R; Mouchahoir T; Schiel J
Anal Bioanal Chem; 2021 Aug; 413(20):4989-5001. PubMed ID: 34231000
[TBL] [Abstract][Full Text] [Related]
18. Insights from native mass spectrometry approaches for top- and middle- level characterization of site-specific antibody-drug conjugates.
Botzanowski T; Erb S; Hernandez-Alba O; Ehkirch A; Colas O; Wagner-Rousset E; Rabuka D; Beck A; Drake PM; Cianférani S
MAbs; 2017 Jul; 9(5):801-811. PubMed ID: 28406343
[TBL] [Abstract][Full Text] [Related]
19. Universal Affinity Capture Liquid Chromatography-Mass Spectrometry Assay for Evaluation of Biotransformation of Site-Specific Antibody Drug Conjugates in Preclinical Studies.
Kotapati S; Passmore D; Yamazoe S; Sanku RKK; Cong Q; Poudel YB; Chowdari NS; Gangwar S; Rao C; Rangan VS; Cardarelli PM; Deshpande S; Strop P; Dollinger G; Rajpal A
Anal Chem; 2020 Jan; 92(2):2065-2073. PubMed ID: 31860282
[TBL] [Abstract][Full Text] [Related]
20. Characterization of drug load variants in a thiol linked antibody-drug conjugate using multidimensional chromatography.
Gilroy JJ; Eakin CM
J Chromatogr B Analyt Technol Biomed Life Sci; 2017 Aug; 1060():182-189. PubMed ID: 28622622
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
