151 related articles for article (PubMed ID: 32422249)
1. Generating therapeutic monoclonal antibodies to complex multi-spanning membrane targets: Overcoming the antigen challenge and enabling discovery strategies.
Dodd R; Schofield DJ; Wilkinson T; Britton ZT
Methods; 2020 Aug; 180():111-126. PubMed ID: 32422249
[TBL] [Abstract][Full Text] [Related]
2. Therapeutic Monoclonal Antibodies to Complex Membrane Protein Targets: Antigen Generation and Antibody Discovery Strategies.
Dodd RB; Wilkinson T; Schofield DJ
BioDrugs; 2018 Aug; 32(4):339-355. PubMed ID: 29934752
[TBL] [Abstract][Full Text] [Related]
3. Discovery of functional monoclonal antibodies targeting G-protein-coupled receptors and ion channels.
Wilkinson TC
Biochem Soc Trans; 2016 Jun; 44(3):831-7. PubMed ID: 27284048
[TBL] [Abstract][Full Text] [Related]
4. Development of therapeutic antibodies to G protein-coupled receptors and ion channels: Opportunities, challenges and their therapeutic potential in respiratory diseases.
Douthwaite JA; Finch DK; Mustelin T; Wilkinson TC
Pharmacol Ther; 2017 Jan; 169():113-123. PubMed ID: 27153991
[TBL] [Abstract][Full Text] [Related]
5. Development of a biochemical and biophysical suite for integral membrane protein targets: A review.
Haffke M; Duckely M; Bergsdorf C; Jaakola VP; Shrestha B
Protein Expr Purif; 2020 Mar; 167():105545. PubMed ID: 31778786
[TBL] [Abstract][Full Text] [Related]
6. A cell-cell interaction format for selection of high-affinity antibodies to membrane proteins.
Yang Z; Wan Y; Tao P; Qiang M; Dong X; Lin CW; Yang G; Zheng T; Lerner RA
Proc Natl Acad Sci U S A; 2019 Jul; 116(30):14971-14978. PubMed ID: 31285332
[TBL] [Abstract][Full Text] [Related]
7. Membrane protein production and formulation for drug discovery.
Gulezian E; Crivello C; Bednenko J; Zafra C; Zhang Y; Colussi P; Hussain S
Trends Pharmacol Sci; 2021 Aug; 42(8):657-674. PubMed ID: 34270922
[TBL] [Abstract][Full Text] [Related]
8. Rapid identification of highly potent human anti-GPCR antagonist monoclonal antibodies.
Scott MJ; Jowett A; Orecchia M; Ertl P; Ouro-Gnao L; Ticehurst J; Gower D; Yates J; Poulton K; Harris C; Mullin MJ; Smith KJ; Lewis AP; Barton N; Washburn ML; de Wildt R
MAbs; 2020; 12(1):1755069. PubMed ID: 32343620
[TBL] [Abstract][Full Text] [Related]
9. Discovery of functional antibodies targeting ion channels.
Wilkinson TC; Gardener MJ; Williams WA
J Biomol Screen; 2015 Apr; 20(4):454-67. PubMed ID: 25473082
[TBL] [Abstract][Full Text] [Related]
10. Screening Strategies for the Discovery of Ion Channel Monoclonal Antibodies.
Colley CS; England E; Linley JE; Wilkinson TCI
Curr Protoc Pharmacol; 2018 Sep; 82(1):e44. PubMed ID: 30168908
[TBL] [Abstract][Full Text] [Related]
11. Engineering therapeutic antibodies targeting G-protein-coupled receptors.
Jo M; Jung ST
Exp Mol Med; 2016 Feb; 48(2):e207. PubMed ID: 26846450
[TBL] [Abstract][Full Text] [Related]
12. A review of antibody-based therapeutics targeting G protein-coupled receptors: an update.
Hutchings CJ
Expert Opin Biol Ther; 2020 Aug; 20(8):925-935. PubMed ID: 32264722
[TBL] [Abstract][Full Text] [Related]
13. Antigen Design for Successful Isolation of Highly Challenging Therapeutic Anti-GPCR Antibodies.
Ju MS; Jung ST
Int J Mol Sci; 2020 Nov; 21(21):. PubMed ID: 33153215
[TBL] [Abstract][Full Text] [Related]
14. Ion channels as therapeutic antibody targets.
Hutchings CJ; Colussi P; Clark TG
MAbs; 2019; 11(2):265-296. PubMed ID: 30526315
[TBL] [Abstract][Full Text] [Related]
15. Drugability of extracellular targets: discovery of small molecule drugs targeting allosteric, functional, and subunit-selective sites on GPCRs and ion channels.
Grigoriadis DE; Hoare SR; Lechner SM; Slee DH; Williams JA
Neuropsychopharmacology; 2009 Jan; 34(1):106-25. PubMed ID: 18800070
[TBL] [Abstract][Full Text] [Related]
16. Opportunities for therapeutic antibodies directed at G-protein-coupled receptors.
Hutchings CJ; Koglin M; Olson WC; Marshall FH
Nat Rev Drug Discov; 2017 Sep; 16(9):787-810. PubMed ID: 28706220
[TBL] [Abstract][Full Text] [Related]
17. Editorial - Membrane protein tools for drug discovery.
Jawhari A
Methods; 2020 Aug; 180():1-2. PubMed ID: 32736003
[No Abstract] [Full Text] [Related]
18. Arrayed protein library technology for therapeutic biologic discovery.
Mao H; Graziano J; Smider VV
Biotechnol Genet Eng Rev; 2012; 28():131-45. PubMed ID: 22616485
[No Abstract] [Full Text] [Related]
19. Production of membrane proteins in industry: The example of GPCRs.
Errey JC; Fiez-Vandal C
Protein Expr Purif; 2020 May; 169():105569. PubMed ID: 31945417
[TBL] [Abstract][Full Text] [Related]
20. Development of an Antigen-Antibody Co-Display System for Detecting Interaction of G-Protein-Coupled Receptors and Single-Chain Variable Fragments.
Zhang Y; Wu BJ; Yu X; Luo P; Ye H; Yu Y; Han W; Li J
Int J Mol Sci; 2021 Apr; 22(9):. PubMed ID: 33946798
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]