BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 32427588)

  • 1. Inhibition of DNAJ-HSP70 interaction improves strength in muscular dystrophy.
    Bengoechea R; Findlay AR; Bhadra AK; Shao H; Stein KC; Pittman SK; Daw JA; Gestwicki JE; True HL; Weihl CC
    J Clin Invest; 2020 Aug; 130(8):4470-4485. PubMed ID: 32427588
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disease-associated mutations within the yeast DNAJB6 homolog Sis1 slow conformer-specific substrate processing and can be corrected by the modulation of nucleotide exchange factors.
    Bhadra AK; Rau MJ; Daw JA; Fitzpatrick JAJ; Weihl CC; True HL
    Nat Commun; 2022 Aug; 13(1):4570. PubMed ID: 35931773
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Myofibrillar disruption and RNA-binding protein aggregation in a mouse model of limb-girdle muscular dystrophy 1D.
    Bengoechea R; Pittman SK; Tuck EP; True HL; Weihl CC
    Hum Mol Genet; 2015 Dec; 24(23):6588-602. PubMed ID: 26362252
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DNAJB6 mutants display toxic gain of function through unregulated interaction with Hsp70 chaperones.
    Abayev-Avraham M; Salzberg Y; Gliksberg D; Oren-Suissa M; Rosenzweig R
    Nat Commun; 2023 Nov; 14(1):7066. PubMed ID: 37923706
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Myopathy-causing mutations in an HSP40 chaperone disrupt processing of specific client conformers.
    Stein KC; Bengoechea R; Harms MB; Weihl CC; True HL
    J Biol Chem; 2014 Jul; 289(30):21120-30. PubMed ID: 24920671
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Exome sequencing identifies a DNAJB6 mutation in a family with dominantly-inherited limb-girdle muscular dystrophy.
    Couthouis J; Raphael AR; Siskind C; Findlay AR; Buenrostro JD; Greenleaf WJ; Vogel H; Day JW; Flanigan KM; Gitler AD
    Neuromuscul Disord; 2014 May; 24(5):431-5. PubMed ID: 24594375
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutations affecting the cytoplasmic functions of the co-chaperone DNAJB6 cause limb-girdle muscular dystrophy.
    Sarparanta J; Jonson PH; Golzio C; Sandell S; Luque H; Screen M; McDonald K; Stajich JM; Mahjneh I; Vihola A; Raheem O; Penttilä S; Lehtinen S; Huovinen S; Palmio J; Tasca G; Ricci E; Hackman P; Hauser M; Katsanis N; Udd B
    Nat Genet; 2012 Feb; 44(4):450-5, S1-2. PubMed ID: 22366786
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel mutations in DNAJB6 gene cause a very severe early-onset limb-girdle muscular dystrophy 1D disease.
    Palmio J; Jonson PH; Evilä A; Auranen M; Straub V; Bushby K; Sarkozy A; Kiuru-Enari S; Sandell S; Pihko H; Hackman P; Udd B
    Neuromuscul Disord; 2015 Nov; 25(11):835-42. PubMed ID: 26338452
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Genetic interaction of hnRNPA2B1 and DNAJB6 in a Drosophila model of multisystem proteinopathy.
    Li S; Zhang P; Freibaum BD; Kim NC; Kolaitis RM; Molliex A; Kanagaraj AP; Yabe I; Tanino M; Tanaka S; Sasaki H; Ross ED; Taylor JP; Kim HJ
    Hum Mol Genet; 2016 Mar; 25(5):936-50. PubMed ID: 26744327
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Exome sequencing reveals DNAJB6 mutations in dominantly-inherited myopathy.
    Harms MB; Sommerville RB; Allred P; Bell S; Ma D; Cooper P; Lopate G; Pestronk A; Weihl CC; Baloh RH
    Ann Neurol; 2012 Mar; 71(3):407-16. PubMed ID: 22334415
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel mutation in DNAJB6, p.(Phe91Leu), in childhood-onset LGMD1D with a severe phenotype.
    Nam TS; Li W; Heo SH; Lee KH; Cho A; Shin JH; Kim YO; Chae JH; Kim DS; Kim MK; Choi SY
    Neuromuscul Disord; 2015 Nov; 25(11):843-51. PubMed ID: 26371419
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Complete loss of the DNAJB6 G/F domain and novel missense mutations cause distal-onset DNAJB6 myopathy.
    Ruggieri A; Brancati F; Zanotti S; Maggi L; Pasanisi MB; Saredi S; Terracciano C; Antozzi C; D Apice MR; Sangiuolo F; Novelli G; Marshall CR; Scherer SW; Morandi L; Federici L; Massa R; Mora M; Minassian BA
    Acta Neuropathol Commun; 2015 Jul; 3():44. PubMed ID: 26205529
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Emerging roles and underlying molecular mechanisms of DNAJB6 in cancer.
    Meng E; Shevde LA; Samant RS
    Oncotarget; 2016 Aug; 7(33):53984-53996. PubMed ID: 27276715
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNAJB6 myopathy in an Asian cohort and cytoplasmic/nuclear inclusions.
    Sato T; Hayashi YK; Oya Y; Kondo T; Sugie K; Kaneda D; Houzen H; Yabe I; Sasaki H; Noguchi S; Nonaka I; Osawa M; Nishino I
    Neuromuscul Disord; 2013 Mar; 23(3):269-76. PubMed ID: 23394708
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pathology of frontotemporal dementia with limb girdle muscular dystrophy caused by a DNAJB6 mutation.
    Yabe I; Tanino M; Yaguchi H; Takiyama A; Cai H; Kanno H; Takahashi I; Hayashi YK; Watanabe M; Takahashi H; Hatakeyama S; Tanaka S; Sasaki H
    Clin Neurol Neurosurg; 2014 Dec; 127():10-2. PubMed ID: 25306414
    [No Abstract]   [Full Text] [Related]  

  • 16. Client processing is altered by novel myopathy-causing mutations in the HSP40 J domain.
    Pullen MY; Weihl CC; True HL
    PLoS One; 2020; 15(6):e0234207. PubMed ID: 32497100
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNAJB6 isoform specific knockdown: Therapeutic potential for limb girdle muscular dystrophy D1.
    Findlay AR; Paing MM; Daw JA; Haller M; Bengoechea R; Pittman SK; Li S; Wang F; Miller TM; True HL; Chou TF; Weihl CC
    Mol Ther Nucleic Acids; 2023 Jun; 32():937-948. PubMed ID: 37346979
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel mutations in DNAJB6 cause LGMD1D and distal myopathy in French families.
    Jonson PH; Palmio J; Johari M; Penttilä S; Evilä A; Nelson I; Bonne G; Wiart N; Meyer V; Boland A; Deleuze JF; Masson C; Stojkovic T; Chapon F; Romero NB; Solé G; Ferrer X; Ferreiro A; Hackman P; Richard I; Udd B
    Eur J Neurol; 2018 May; 25(5):790-794. PubMed ID: 29437287
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Intrafamilial variability of limb-girdle muscular dystrophy, LGMD1D type.
    Zima J; Eaton A; Pál E; Till Á; Ito YA; Warman-Chardon J; Hartley T; Cagnone G; Melegh BI; ; Boycott KM; Melegh B; Hadzsiev K
    Eur J Med Genet; 2020 Feb; 63(2):103655. PubMed ID: 31034989
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Versatile members of the DNAJ family show Hsp70 dependent anti-aggregation activity on RING1 mutant parkin C289G.
    Kakkar V; Kuiper EF; Pandey A; Braakman I; Kampinga HH
    Sci Rep; 2016 Oct; 6():34830. PubMed ID: 27713507
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.