159 related articles for article (PubMed ID: 32429388)
1. Retina-Targeted Delivery of 17β-Estradiol by the Topically Applied DHED Prodrug.
Prokai-Tatrai K; Nguyen V; De La Cruz DL; Guerra R; Zaman K; Rahlouni F; Prokai L
Pharmaceutics; 2020 May; 12(5):. PubMed ID: 32429388
[TBL] [Abstract][Full Text] [Related]
2. Proteomics-Based Retinal Target Engagement Analysis and Retina-Targeted Delivery of 17β-Estradiol by the DHED Prodrug for Ocular Neurotherapy in Males.
Prokai-Tatrai K; Zaman K; Nguyen V; De La Cruz DL; Prokai L
Pharmaceutics; 2021 Sep; 13(9):. PubMed ID: 34575465
[TBL] [Abstract][Full Text] [Related]
3. 10β,17α-Dihydroxyestra-1,4-dien-3-one: A Bioprecursor Prodrug Preferentially Producing 17α-Estradiol in the Brain for Targeted Neurotherapy.
Prokai-Tatrai K; Nguyen V; Prokai L
ACS Chem Neurosci; 2018 Nov; 9(11):2528-2533. PubMed ID: 29843514
[TBL] [Abstract][Full Text] [Related]
4. The prodrug DHED selectively delivers 17β-estradiol to the brain for treating estrogen-responsive disorders.
Prokai L; Nguyen V; Szarka S; Garg P; Sabnis G; Bimonte-Nelson HA; McLaughlin KJ; Talboom JS; Conrad CD; Shughrue PJ; Gould TD; Brodie A; Merchenthaler I; Koulen P; Prokai-Tatrai K
Sci Transl Med; 2015 Jul; 7(297):297ra113. PubMed ID: 26203081
[TBL] [Abstract][Full Text] [Related]
5. Brain-Selective Estrogen Therapy Prevents Androgen Deprivation-Associated Hot Flushes in a Rat Model.
Merchenthaler I; Lane M; Stennett C; Zhan M; Nguyen V; Prokai-Tatrai K; Prokai L
Pharmaceuticals (Basel); 2020 Jun; 13(6):. PubMed ID: 32531919
[TBL] [Abstract][Full Text] [Related]
6. A comparative evaluation of treatments with 17β-estradiol and its brain-selective prodrug in a double-transgenic mouse model of Alzheimer's disease.
Tschiffely AE; Schuh RA; Prokai-Tatrai K; Prokai L; Ottinger MA
Horm Behav; 2016 Jul; 83():39-44. PubMed ID: 27210479
[TBL] [Abstract][Full Text] [Related]
7. Treatment with a brain-selective prodrug of 17β-estradiol improves cognitive function in Alzheimer's disease mice by regulating klf5-NF-κB pathway.
Yan W; Wu J; Song B; Luo Q; Xu Y
Naunyn Schmiedebergs Arch Pharmacol; 2019 Jul; 392(7):879-886. PubMed ID: 30879099
[TBL] [Abstract][Full Text] [Related]
8. Treatment with an orally bioavailable prodrug of 17β-estradiol alleviates hot flushes without hormonal effects in the periphery.
Merchenthaler I; Lane M; Sabnis G; Brodie A; Nguyen V; Prokai L; Prokai-Tatrai K
Sci Rep; 2016 Aug; 6():30721. PubMed ID: 27477453
[TBL] [Abstract][Full Text] [Related]
9. Intranasal administration of DHED protects against exhaustive exercise-induced brain injury in rats.
Peng G; Zheng H; Wu C; Wu C; Ma X; Xiong J; Hou J; Zhang L; Yang L; Pan H
Brain Res; 2021 Dec; 1772():147665. PubMed ID: 34562473
[TBL] [Abstract][Full Text] [Related]
10. A Novel Prodrug Approach for Central Nervous System-Selective Estrogen Therapy.
Prokai-Tatrai K; Prokai L
Molecules; 2019 Nov; 24(22):. PubMed ID: 31752337
[TBL] [Abstract][Full Text] [Related]
11. An exploratory investigation of brain-selective estrogen treatment in males using a mouse model of Alzheimer's disease.
Tschiffely AE; Schuh RA; Prokai-Tatrai K; Ottinger MA; Prokai L
Horm Behav; 2018 Feb; 98():16-21. PubMed ID: 29183688
[TBL] [Abstract][Full Text] [Related]
12. A Green Blue LED-Driven Two-Liquid-Phase One-Pot Procedure for the Synthesis of Estrogen-Related Quinol Prodrugs.
De Marchi E; Botta L; Bizzarri BM; Saladino R
Molecules; 2022 Dec; 27(24):. PubMed ID: 36558094
[TBL] [Abstract][Full Text] [Related]
13. The impact of 17β-estradiol on the estrogen-deficient female brain: from mechanisms to therapy with hot flushes as target symptoms.
Prokai-Tatrai K; Prokai L
Front Endocrinol (Lausanne); 2023; 14():1310432. PubMed ID: 38260155
[TBL] [Abstract][Full Text] [Related]
14. Brain Specific Estrogen Ameliorates Cognitive Effects of Surgical Menopause in Mice.
Salinero AE; Abi-Ghanem C; Venkataganesh H; Sura A; Smith RM; Thrasher CA; Kelly RD; Hatcher KM; NyBlom V; Shamlian V; Kyaw NR; Belanger KM; Gannon OJ; Stephens SBZ; Zuloaga DG; Zuloaga KL
bioRxiv; 2023 Aug; ():. PubMed ID: 37609180
[TBL] [Abstract][Full Text] [Related]
15. 17β-estradiol eye drops protect the retinal ganglion cell layer and preserve visual function in an in vivo model of glaucoma.
Prokai-Tatrai K; Xin H; Nguyen V; Szarka S; Blazics B; Prokai L; Koulen P
Mol Pharm; 2013 Aug; 10(8):3253-61. PubMed ID: 23841874
[TBL] [Abstract][Full Text] [Related]
16. Practical one-pot conversion of 17beta-estradiol to 10beta-hydroxy- (p-quinol) and 10beta-chloro-17beta-hydroxyestra-1,4-dien-3-one.
Lista L; Manini P; Napolitano A; Pezzella A; d'Ischia M
Steroids; 2006 Aug; 71(8):670-3. PubMed ID: 16730767
[TBL] [Abstract][Full Text] [Related]
17. Development of a Δ9-Tetrahydrocannabinol Amino Acid-Dicarboxylate Prodrug With Improved Ocular Bioavailability.
Adelli GR; Bhagav P; Taskar P; Hingorani T; Pettaway S; Gul W; ElSohly MA; Repka MA; Majumdar S
Invest Ophthalmol Vis Sci; 2017 Apr; 58(4):2167-2179. PubMed ID: 28399267
[TBL] [Abstract][Full Text] [Related]
18. Bioavailability and anticataract effects of a topical ocular drug delivery system containing disulfiram and hydroxypropyl-beta-cyclodextrin on selenite-treated rats.
Wang S; Li D; Ito Y; Nabekura T; Wang S; Zhang J; Wu C
Curr Eye Res; 2004 Jul; 29(1):51-8. PubMed ID: 15370367
[TBL] [Abstract][Full Text] [Related]
19. 17β-Estradiol Delivered in Eye Drops: Evidence of Impact on Protein Networks and Associated Biological Processes in the Rat Retina through Quantitative Proteomics.
Prokai L; Zaman K; Nguyen V; Prokai-Tatrai K
Pharmaceutics; 2020 Jan; 12(2):. PubMed ID: 32012756
[TBL] [Abstract][Full Text] [Related]
20. "All in the mind"? Brain-targeting chemical delivery system of 17β-estradiol (Estredox) produces significant uterotrophic side effect.
Prokai-Tatrai K; Szarka S; Nguyen V; Sahyouni F; Walker C; White S; Talamantes T; Prokai L
Pharm Anal Acta; 2012; Suppl 7():. PubMed ID: 24380028
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]