These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

254 related articles for article (PubMed ID: 32435917)

  • 1. Constitutive androstane receptor (CAR) mediates dieldrin-induced liver tumorigenesis in mouse.
    Wang Z; Wu Q; Li X; Klaunig JE
    Arch Toxicol; 2020 Aug; 94(8):2873-2884. PubMed ID: 32435917
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis.
    Fisher CD; Jackson JP; Lickteig AJ; Augustine LM; Cherrington NJ
    Arch Toxicol; 2008 Dec; 82(12):959-64. PubMed ID: 18488193
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The role of mouse and human peroxisome proliferator-activated receptor-α in modulating the hepatic effects of perfluorooctane sulfonate in mice.
    Su S; Billy LJ; Chang S; Gonzalez FJ; Patterson AD; Peters JM
    Toxicology; 2022 Jan; 465():153056. PubMed ID: 34861291
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Perfluorocarboxylic acids induce cytochrome P450 enzymes in mouse liver through activation of PPAR-alpha and CAR transcription factors.
    Cheng X; Klaassen CD
    Toxicol Sci; 2008 Nov; 106(1):29-36. PubMed ID: 18648086
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Toxaphene-induced mouse liver tumorigenesis is mediated by the constitutive androstane receptor.
    Wang Z; Li X; Wu Q; Lamb JC; Klaunig JE
    J Appl Toxicol; 2017 Aug; 37(8):967-975. PubMed ID: 28218408
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor.
    Ren H; Aleksunes LM; Wood C; Vallanat B; George MH; Klaassen CD; Corton JC
    Toxicol Sci; 2010 Jan; 113(1):45-59. PubMed ID: 19850644
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice.
    Shizu R; Benoki S; Numakura Y; Kodama S; Miyata M; Yamazoe Y; Yoshinari K
    PLoS One; 2013; 8(4):e61802. PubMed ID: 23626729
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response.
    Wei P; Zhang J; Dowhan DH; Han Y; Moore DD
    Pharmacogenomics J; 2002; 2(2):117-26. PubMed ID: 12049174
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Methyl isobutyl ketone-induced hepatocellular carcinogenesis in B6C3F
    Hughes BJ; Thomas J; Lynch AM; Borghoff SJ; Green S; Mensing T; Sarang SS; LeBaron MJ
    Regul Toxicol Pharmacol; 2016 Nov; 81():421-429. PubMed ID: 27664318
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human constitutive androstane receptor (CAR) and pregnane X receptor (PXR) support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogens phenobarbital and chlordane in vivo.
    Ross J; Plummer SM; Rode A; Scheer N; Bower CC; Vogel O; Henderson CJ; Wolf CR; Elcombe CR
    Toxicol Sci; 2010 Aug; 116(2):452-66. PubMed ID: 20403969
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of nuclear receptor-mediated murine hepatocarcinogenesis of the herbicide pronamide and its human relevance.
    LeBaron MJ; Rasoulpour RJ; Gollapudi BB; Sura R; Kan HL; Schisler MR; Pottenger LH; Papineni S; Eisenbrandt DL
    Toxicol Sci; 2014 Nov; 142(1):74-92. PubMed ID: 25092647
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chemical Activation of the Constitutive Androstane Receptor Leads to Activation of Oxidant-Induced Nrf2.
    Rooney JP; Oshida K; Kumar R; Baldwin WS; Corton JC
    Toxicol Sci; 2019 Jan; 167(1):172-189. PubMed ID: 30203046
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Involvement of Mouse Constitutive Androstane Receptor in Acifluorfen-Induced Liver Injury and Subsequent Tumor Development.
    Kuwata K; Inoue K; Ichimura R; Takahashi M; Kodama Y; Shibutani M; Yoshida M
    Toxicol Sci; 2016 Jun; 151(2):271-85. PubMed ID: 26928356
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of hepatic xenosensor function by HNF4alpha.
    Kotulkar M; Paine-Cabrera D; Robarts DR; Apte U
    Toxicol Sci; 2024 Aug; 200(2):346-356. PubMed ID: 38810120
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Stilbene compound trans-3,4,5,4´-tetramethoxystilbene, a potential anticancer drug, regulates constitutive androstane receptor (Car) target genes, but does not possess proliferative activity in mouse liver.
    Dusek J; Skoda J; Holas O; Horvatova A; Smutny T; Linhartova L; Hirsova P; Kucera O; Micuda S; Braeuning A; Pavek P
    Toxicol Lett; 2019 Oct; 313():1-10. PubMed ID: 31170421
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Essential role of constitutive androstane receptor in Ginkgo biloba extract induced liver hypertrophy and hepatocarcinogenesis.
    Maeda J; Inoue K; Ichimura R; Takahashi M; Kodama Y; Saito N; Yoshida M
    Food Chem Toxicol; 2015 Sep; 83():201-9. PubMed ID: 26115596
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Induction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor alpha synthetic ligands in mouse liver.
    Guo D; Sarkar J; Suino-Powell K; Xu Y; Matsumoto K; Jia Y; Yu S; Khare S; Haldar K; Rao MS; Foreman JE; Monga SP; Peters JM; Xu HE; Reddy JK
    J Biol Chem; 2007 Dec; 282(50):36766-76. PubMed ID: 17962186
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Investigation of the mechanism of triclosan induced mouse liver tumors.
    Wang Z; Li X; Klaunig JE
    Regul Toxicol Pharmacol; 2017 Jun; 86():137-147. PubMed ID: 28267557
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Piperonyl butoxide: Mode of action analysis for mouse liver tumour formation and human relevance.
    Lake BG; Price RJ; Scott MP; Chatham LR; Vardy A; Osimitz TG
    Toxicology; 2020 Jun; 439():152465. PubMed ID: 32320717
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mode of action of dieldrin-induced liver tumors: application to human risk assessment.
    Klaunig JE; Cohen SM
    Crit Rev Toxicol; 2024 Oct; 54(9):634-658. PubMed ID: 39077834
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.