BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

260 related articles for article (PubMed ID: 32437509)

  • 1. PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2.
    Xu X; Hou B; Fulzele A; Masubuchi T; Zhao Y; Wu Z; Hu Y; Jiang Y; Ma Y; Wang H; Bennett EJ; Fu G; Hui E
    J Cell Biol; 2020 Jun; 219(6):. PubMed ID: 32437509
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular features underlying differential SHP1/SHP2 binding of immune checkpoint receptors.
    Xu X; Masubuchi T; Cai Q; Zhao Y; Hui E
    Elife; 2021 Nov; 10():. PubMed ID: 34734802
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy.
    Celis-Gutierrez J; Blattmann P; Zhai Y; Jarmuzynski N; Ruminski K; Grégoire C; Ounoughene Y; Fiore F; Aebersold R; Roncagalli R; Gstaiger M; Malissen B
    Cell Rep; 2019 Jun; 27(11):3315-3330.e7. PubMed ID: 31189114
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A THEMIS:SHP1 complex promotes T-cell survival.
    Paster W; Bruger AM; Katsch K; Grégoire C; Roncagalli R; Fu G; Gascoigne NR; Nika K; Cohnen A; Feller SM; Simister PC; Molder KC; Cordoba SP; Dushek O; Malissen B; Acuto O
    EMBO J; 2015 Feb; 34(3):393-409. PubMed ID: 25535246
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Themis-associated phosphatase activity controls signaling in T cell development.
    Mehta M; Brzostek J; Chen EW; Tung DWH; Chen S; Sankaran S; Yap J; Rybakin V; Gascoigne NRJ
    Proc Natl Acad Sci U S A; 2018 Nov; 115(48):E11331-E11340. PubMed ID: 30413615
    [TBL] [Abstract][Full Text] [Related]  

  • 6. B and T lymphocyte attenuator-mediated signal transduction provides a potent inhibitory signal to primary human CD4 T cells that can be initiated by multiple phosphotyrosine motifs.
    Chemnitz JM; Lanfranco AR; Braunstein I; Riley JL
    J Immunol; 2006 Jun; 176(11):6603-14. PubMed ID: 16709818
    [TBL] [Abstract][Full Text] [Related]  

  • 7. THEMIS promotes T cell development and maintenance by rising the signaling threshold of the inhibitory receptor BTLA.
    Mélique S; Vadel A; Rouquié N; Yang C; Bories C; Cotineau C; Saoudi A; Fazilleau N; Lesourne R
    Proc Natl Acad Sci U S A; 2024 May; 121(20):e2318773121. PubMed ID: 38713628
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Affinity purification mass spectrometry analysis of PD-1 uncovers SAP as a new checkpoint inhibitor.
    Peled M; Tocheva AS; Sandigursky S; Nayak S; Philips EA; Nichols KE; Strazza M; Azoulay-Alfaguter I; Askenazi M; Neel BG; Pelzek AJ; Ueberheide B; Mor A
    Proc Natl Acad Sci U S A; 2018 Jan; 115(3):E468-E477. PubMed ID: 29282323
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The BTLA and PD-1 signaling pathways independently regulate the proliferation and cytotoxicity of human peripheral blood γδ T cells.
    Hwang HJ; Lee JJ; Kang SH; Suh JK; Choi ES; Jang S; Hwang SH; Koh KN; Im HJ; Kim N
    Immun Inflamm Dis; 2021 Mar; 9(1):274-287. PubMed ID: 33332777
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1.
    Watanabe N; Gavrieli M; Sedy JR; Yang J; Fallarino F; Loftin SK; Hurchla MA; Zimmerman N; Sim J; Zang X; Murphy TL; Russell JH; Allison JP; Murphy KM
    Nat Immunol; 2003 Jul; 4(7):670-9. PubMed ID: 12796776
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tyrosine phosphatases Shp1 and Shp2 have unique and opposing roles in oligodendrocyte development.
    Kuo E; Park DK; Tzvetanova ID; Leiton CV; Cho BS; Colognato H
    J Neurochem; 2010 Apr; 113(1):200-12. PubMed ID: 20132481
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Exploration of T cell immune responses by expression of a dominant-negative SHP1 and SHP2.
    Taylor J; Bulek A; Gannon I; Robson M; Kokalaki E; Grothier T; McKenzie C; El-Kholy M; Stavrou M; Traynor-White C; Lim WC; Panagiotou P; Srivastava S; Baldan V; Sillibourne J; Ferrari M; Pule M; Thomas S
    Front Immunol; 2023; 14():1119350. PubMed ID: 37334382
    [TBL] [Abstract][Full Text] [Related]  

  • 13. HTLV-1 bZIP Factor Enhances T-Cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory Receptors.
    Kinosada H; Yasunaga JI; Shimura K; Miyazato P; Onishi C; Iyoda T; Inaba K; Matsuoka M
    PLoS Pathog; 2017 Jan; 13(1):e1006120. PubMed ID: 28046066
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Uncoupling ITIM receptor G6b-B from tyrosine phosphatases Shp1 and Shp2 disrupts murine platelet homeostasis.
    Geer MJ; van Geffen JP; Gopalasingam P; Vögtle T; Smith CW; Heising S; Kuijpers MJE; Tullemans BME; Jarvis GE; Eble JA; Jeeves M; Overduin M; Heemskerk JWM; Mazharian A; Senis YA
    Blood; 2018 Sep; 132(13):1413-1425. PubMed ID: 29891536
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of phosphotyrosine binding motifs in the cytoplasmic domain of B and T lymphocyte attenuator required for association with protein tyrosine phosphatases SHP-1 and SHP-2.
    Gavrieli M; Watanabe N; Loftin SK; Murphy TL; Murphy KM
    Biochem Biophys Res Commun; 2003 Dec; 312(4):1236-43. PubMed ID: 14652006
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dephosphorylation of ZAP-70 and inhibition of T cell activation by activated SHP1.
    Brockdorff J; Williams S; Couture C; Mustelin T
    Eur J Immunol; 1999 Aug; 29(8):2539-50. PubMed ID: 10458769
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SHP2 Targets ITK Downstream of PD-1 to Inhibit T Cell Function.
    Strazza M; Adam K; Lerrer S; Straube J; Sandigursky S; Ueberheide B; Mor A
    Inflammation; 2021 Aug; 44(4):1529-1539. PubMed ID: 33624224
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2.
    Yokosuka T; Takamatsu M; Kobayashi-Imanishi W; Hashimoto-Tane A; Azuma M; Saito T
    J Exp Med; 2012 Jun; 209(6):1201-17. PubMed ID: 22641383
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dual inhibition of BTLA and PD-1 can enhance therapeutic efficacy of paclitaxel on intraperitoneally disseminated tumors.
    Sun WZ; Lin HW; Chen WY; Chien CL; Lai YL; Chen J; Chen YL; Cheng WF
    J Immunother Cancer; 2023 Jul; 11(7):. PubMed ID: 37463789
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis.
    Mintz MA; Felce JH; Chou MY; Mayya V; Xu Y; Shui JW; An J; Li Z; Marson A; Okada T; Ware CF; Kronenberg M; Dustin ML; Cyster JG
    Immunity; 2019 Aug; 51(2):310-323.e7. PubMed ID: 31204070
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.