These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

105 related articles for article (PubMed ID: 32437601)

  • 1. Ionotropic Glutamate Receptor GluA2 in Complex with Bicyclic Pyrimidinedione-Based Compounds: When Small Compound Modifications Have Distinct Effects on Binding Interactions.
    Frydenvang K; Pickering DS; Kshirsagar GU; Chemi G; Gemma S; Sprogøe D; Kærn AM; Brogi S; Campiani G; Butini S; Kastrup JS
    ACS Chem Neurosci; 2020 Jun; 11(12):1791-1800. PubMed ID: 32437601
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure and Affinity of Two Bicyclic Glutamate Analogues at AMPA and Kainate Receptors.
    Møllerud S; Pinto A; Marconi L; Frydenvang K; Thorsen TS; Laulumaa S; Venskutonytė R; Winther S; Moral AMC; Tamborini L; Conti P; Pickering DS; Kastrup JS
    ACS Chem Neurosci; 2017 Sep; 8(9):2056-2064. PubMed ID: 28691798
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacological and structural characterization of conformationally restricted (S)-glutamate analogues at ionotropic glutamate receptors.
    Juknaitė L; Venskutonytė R; Assaf Z; Faure S; Gefflaut T; Aitken DJ; Nielsen B; Gajhede M; Kastrup JS; Bunch L; Frydenvang K; Pickering DS
    J Struct Biol; 2012 Oct; 180(1):39-46. PubMed ID: 22789682
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chemoenzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters.
    Assaf Z; Larsen AP; Venskutonytė R; Han L; Abrahamsen B; Nielsen B; Gajhede M; Kastrup JS; Jensen AA; Pickering DS; Frydenvang K; Gefflaut T; Bunch L
    J Med Chem; 2013 Feb; 56(4):1614-28. PubMed ID: 23414088
    [TBL] [Abstract][Full Text] [Related]  

  • 5. L-Asp is a useful tool in the purification of the ionotropic glutamate receptor A2 ligand-binding domain.
    Krintel C; Frydenvang K; Ceravalls de Rabassa A; Kaern AM; Gajhede M; Pickering DS; Kastrup JS
    FEBS J; 2014 May; 281(10):2422-30. PubMed ID: 24673938
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2.
    Krintel C; Frydenvang K; Olsen L; Kristensen MT; de Barrios O; Naur P; Francotte P; Pirotte B; Gajhede M; Kastrup JS
    Biochem J; 2012 Jan; 441(1):173-8. PubMed ID: 21895609
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and Pharmacology of Mono-, Di-, and Trialkyl-Substituted 7-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides Combined with X-ray Structure Analysis to Understand the Unexpected Structure-Activity Relationship at AMPA Receptors.
    Larsen AP; Francotte P; Frydenvang K; Tapken D; Goffin E; Fraikin P; Caignard DH; Lestage P; Danober L; Pirotte B; Kastrup JS
    ACS Chem Neurosci; 2016 Mar; 7(3):378-90. PubMed ID: 26771108
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Aryl- and heteroaryl-substituted phenylalanines as AMPA receptor ligands.
    Szymańska E; Chałupnik P; Johansen TN; Nielsen B; Cuñado Moral AM; Pickering DS; Więckowska A; Kieć-Kononowicz K
    Chem Biol Drug Des; 2017 Dec; 90(6):1271-1281. PubMed ID: 28636281
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural analysis of the positive AMPA receptor modulators CX516 and Me-CX516 in complex with the GluA2 ligand-binding domain.
    Krintel C; Harpsøe K; Zachariassen LG; Peters D; Frydenvang K; Pickering DS; Gajhede M; Kastrup JS
    Acta Crystallogr D Biol Crystallogr; 2013 Sep; 69(Pt 9):1645-52. PubMed ID: 23999288
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Quantifying water-mediated protein-ligand interactions in a glutamate receptor: a DFT study.
    Sahai MA; Biggin PC
    J Phys Chem B; 2011 Jun; 115(21):7085-96. PubMed ID: 21545106
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacological characterization and binding modes of novel racemic and optically active phenylalanine-based antagonists of AMPA receptors.
    Szymańska E; Nielsen B; Johansen TN; Cuñado Moral AM; Pickering DS; Szczepańska K; Mickowska A; Kieć-Kononowicz K
    Eur J Med Chem; 2017 Sep; 138():874-883. PubMed ID: 28738307
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2.
    Krintel C; Dorosz J; Larsen AH; Thorsen TS; Venskutonytė R; Mirza O; Gajhede M; Boesen T; Kastrup JS
    FEBS J; 2021 Feb; 288(3):995-1007. PubMed ID: 32543078
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Studies on Aryl-Substituted Phenylalanines: Synthesis, Activity, and Different Binding Modes at AMPA Receptors.
    Szymanska E; Frydenvang K; Pickering DS; Krintel C; Nielsen B; Kooshki A; Zachariassen LG; Olsen L; Kastrup JS; Johansen TN
    J Med Chem; 2016 Jan; 59(1):448-61. PubMed ID: 26653877
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Enthalpy-Entropy Compensation in the Binding of Modulators at Ionotropic Glutamate Receptor GluA2.
    Krintel C; Francotte P; Pickering DS; Juknaitė L; Pøhlsgaard J; Olsen L; Frydenvang K; Goffin E; Pirotte B; Kastrup JS
    Biophys J; 2016 Jun; 110(11):2397-2406. PubMed ID: 27276258
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural and pharmacological characterization of phenylalanine-based AMPA receptor antagonists at kainate receptors.
    Venskutonytė R; Frydenvang K; Valadés EA; Szymańska E; Johansen TN; Kastrup JS; Pickering DS
    ChemMedChem; 2012 Oct; 7(10):1793-8. PubMed ID: 22407805
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Small-angle neutron scattering studies on the AMPA receptor GluA2 in the resting, AMPA-bound and GYKI-53655-bound states.
    Larsen AH; Dorosz J; Thorsen TS; Johansen NT; Darwish T; Midtgaard SR; Arleth L; Kastrup JS
    IUCrJ; 2018 Nov; 5(Pt 6):780-793. PubMed ID: 30443361
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A comparative analysis of the role of water in the binding pockets of ionotropic glutamate receptors.
    Vijayan R; Sahai MA; Czajkowski T; Biggin PC
    Phys Chem Chem Phys; 2010 Nov; 12(42):14057-66. PubMed ID: 20856958
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure-Activity Relationship Study of Ionotropic Glutamate Receptor Antagonist (2S,3R)-3-(3-Carboxyphenyl)pyrrolidine-2-carboxylic Acid.
    Krogsgaard-Larsen N; Storgaard M; Møller C; Demmer CS; Hansen J; Han L; Monrad RN; Nielsen B; Tapken D; Pickering DS; Kastrup JS; Frydenvang K; Bunch L
    J Med Chem; 2015 Aug; 58(15):6131-50. PubMed ID: 26200741
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The structure of a mixed GluR2 ligand-binding core dimer in complex with (S)-glutamate and the antagonist (S)-NS1209.
    Kasper C; Pickering DS; Mirza O; Olsen L; Kristensen AS; Greenwood JR; Liljefors T; Schousboe A; Wätjen F; Gajhede M; Sigurskjold BW; Kastrup JS
    J Mol Biol; 2006 Apr; 357(4):1184-201. PubMed ID: 16483599
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutational Analysis and Modeling of Negative Allosteric Modulator Binding Sites in AMPA Receptors.
    Stenum-Berg C; Musgaard M; Chavez-Abiega S; Thisted CL; Barrella L; Biggin PC; Kristensen AS
    Mol Pharmacol; 2019 Dec; 96(6):835-850. PubMed ID: 31582576
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.