BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

102 related articles for article (PubMed ID: 3243791)

  • 1. High-performance liquid chromatographic assay for mexiletine hydroxylation in microsomes of human liver.
    Broly F; Libersa C; Lhermitte M
    J Chromatogr; 1988 Oct; 431(2):369-78. PubMed ID: 3243791
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Simultaneous determination of mexiletine and four hydroxylated metabolites in human serum by high-performance liquid chromatography and its application to pharmacokinetic studies.
    Paczkowski D; Filipek M; Mielniczuk Z; Andrzejczak J; Popławska W; Sitkiewicz D
    J Chromatogr; 1992 Jan; 573(2):235-46. PubMed ID: 1601956
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibitory studies of mexiletine and dextromethorphan oxidation in human liver microsomes.
    Broly F; Libersa C; Lhermitte M; Dupuis B
    Biochem Pharmacol; 1990 Mar; 39(6):1045-53. PubMed ID: 2322292
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Direct analysis of the enantiomers of mexiletine and its metabolites in plasma and urine using an HPLC-CSP.
    Fieger H; Wainer IW
    J Pharm Biomed Anal; 1993; 11(11-12):1173-9. PubMed ID: 8123732
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Influence of the CYP2D6*10 allele on the metabolism of mexiletine by human liver microsomes.
    Senda C; Yamaura Y; Kobayashi K; Fujii H; Minami H; Sasaki Y; Igarashi T; Chiba K
    Br J Clin Pharmacol; 2001 Jul; 52(1):100-3. PubMed ID: 11453897
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mexiletine metabolism in vitro by human liver.
    Broly F; Libersa C; Lhermitte M
    Drug Metab Dispos; 1990; 18(3):362-8. PubMed ID: 1974200
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Stereoselective metabolism of rac-mexiletine by the fungus Cunninghamella echinulata yields the major human metabolites hydroxymethylmexiletine and p-hydroxymexiletine.
    Freitag DG; Foster RT; Coutts RT; Pickard MA; Pasutto FM
    Drug Metab Dispos; 1997 Jun; 25(6):685-92. PubMed ID: 9193869
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacokinetics of mexiletine and its metabolites, hydroxymethylmexiletine and p-hydroxymexiletine, after single oral administration in healthy subjects.
    Paczkowski D; Sadowski Z; Filipek M; Koliński P
    Pol J Pharmacol Pharm; 1990; 42(4):365-75. PubMed ID: 2097598
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enantioselective determination of the hydroxylated metabolites of mexiletine in human plasma.
    Lanchote VL; Bonato PS; Cesarino EJ; Mere Júnior YA; Cavani SR; Santos J; Bertucci C
    Chirality; 1997; 9(8):732-8. PubMed ID: 9435098
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Enantioselective determination of mexiletine and its metabolites p-hydroxymexiletine and hydroxymethylmexiletine in rat plasma by normal-phase liquid chromatography-tandem mass spectrometry: application to pharmacokinetics.
    Godoy AL; Parisi CC; Marques MP; Coelho EB; Lanchote VL
    Chirality; 2009 Jul; 21(7):648-56. PubMed ID: 18973279
    [TBL] [Abstract][Full Text] [Related]  

  • 11. High-performance liquid chromatographic method for resolving the enantiomers of mexiletine and two major metabolites isolated from microbial fermentation media.
    Freitag DG; Foster RT; Coutts RT; Pasutto FM
    J Chromatogr; 1993 Jul; 616(2):253-9. PubMed ID: 8376507
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The metabolism of mexiletine in relation to the debrisoquine/sparteine-type polymorphism of drug oxidation.
    Broly F; Vandamme N; Libersa C; Lhermitte M
    Br J Clin Pharmacol; 1991 Oct; 32(4):459-66. PubMed ID: 1958440
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of cigarette smoking on mexiletine kinetics.
    Grech-Bélanger O; Gilbert M; Turgeon J; LeBlanc PP
    Clin Pharmacol Ther; 1985 Jun; 37(6):638-43. PubMed ID: 4006363
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Meta-hydroxymexiletine, a new metabolite of mexiletine. Isolation, characterization, and species differences in its formation.
    Grech-Bélanger O; Turgeon J; Lalande M; Bélanger PM
    Drug Metab Dispos; 1991; 19(2):458-61. PubMed ID: 1676654
    [TBL] [Abstract][Full Text] [Related]  

  • 15. NADPH-dependent metabolism of estrone by human liver microsomes.
    Lee AJ; Mills LH; Kosh JW; Conney AH; Zhu BT
    J Pharmacol Exp Ther; 2002 Mar; 300(3):838-49. PubMed ID: 11861789
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Determination of species-difference in microsomal metabolism of amitriptyline using a predictive MRM-IDA-EPI method.
    Lee JY; Lee SY; Lee K; Oh SJ; Kim SK
    Chem Biol Interact; 2015 Mar; 229():109-18. PubMed ID: 25623954
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of the NADPH-dependent metabolism of 17beta-estradiol to multiple metabolites by human liver microsomes and selectively expressed human cytochrome P450 3A4 and 3A5.
    Lee AJ; Kosh JW; Conney AH; Zhu BT
    J Pharmacol Exp Ther; 2001 Aug; 298(2):420-32. PubMed ID: 11454902
    [TBL] [Abstract][Full Text] [Related]  

  • 18. High-performance liquid chromatographic separation of potential hydroxylated metabolites of estradiol 17-sulfate by female rat liver microsomes.
    Itoh Y; Takanashi K; Itoh S; Yoshizawa I
    Anal Sci; 2001 May; 17(5):659-61. PubMed ID: 11708150
    [No Abstract]   [Full Text] [Related]  

  • 19. Validation of a novel in vitro assay using ultra performance liquid chromatography-mass spectrometry (UPLC/MS) to detect and quantify hydroxylated metabolites of BDE-99 in rat liver microsomes.
    Erratico CA; Szeitz A; Bandiera SM
    J Chromatogr B Analyt Technol Biomed Life Sci; 2010 Jun; 878(19):1562-8. PubMed ID: 20451473
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Simultaneous quantitation of lidocaine and its four metabolites by high-performance liquid chromatography: application to studies on in vitro and in vivo metabolism of lidocaine in rats.
    Kawai R; Fujita S; Suzuki T
    J Pharm Sci; 1985 Nov; 74(11):1219-24. PubMed ID: 4087184
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.