209 related articles for article (PubMed ID: 32439803)
1. Hypoxia drives the assembly of the multienzyme purinosome complex.
Doigneaux C; Pedley AM; Mistry IN; Papayova M; Benkovic SJ; Tavassoli A
J Biol Chem; 2020 Jul; 295(28):9551-9566. PubMed ID: 32439803
[TBL] [Abstract][Full Text] [Related]
2. Mutations of ATIC and ADSL affect purinosome assembly in cultured skin fibroblasts from patients with AICA-ribosiduria and ADSL deficiency.
Baresova V; Skopova V; Sikora J; Patterson D; Sovova J; Zikanova M; Kmoch S
Hum Mol Genet; 2012 Apr; 21(7):1534-43. PubMed ID: 22180458
[TBL] [Abstract][Full Text] [Related]
3. AMPK Activation via Modulation of De Novo Purine Biosynthesis with an Inhibitor of ATIC Homodimerization.
Asby DJ; Cuda F; Beyaert M; Houghton FD; Cagampang FR; Tavassoli A
Chem Biol; 2015 Jul; 22(7):838-48. PubMed ID: 26144885
[TBL] [Abstract][Full Text] [Related]
4. Bifunctional enzyme ATIC promotes propagation of hepatocellular carcinoma by regulating AMPK-mTOR-S6 K1 signaling.
Li M; Jin C; Xu M; Zhou L; Li D; Yin Y
Cell Commun Signal; 2017 Dec; 15(1):52. PubMed ID: 29246230
[TBL] [Abstract][Full Text] [Related]
5. Quantitative analysis of purine nucleotides indicates that purinosomes increase de novo purine biosynthesis.
Zhao H; Chiaro CR; Zhang L; Smith PB; Chan CY; Pedley AM; Pugh RJ; French JB; Patterson AD; Benkovic SJ
J Biol Chem; 2015 Mar; 290(11):6705-13. PubMed ID: 25605736
[TBL] [Abstract][Full Text] [Related]
6. High-glucose toxicity is mediated by AICAR-transformylase/IMP cyclohydrolase and mitigated by AMP-activated protein kinase in
Riedinger C; Mendler M; Schlotterer A; Fleming T; Okun J; Hammes HP; Herzig S; Nawroth PP
J Biol Chem; 2018 Mar; 293(13):4845-4859. PubMed ID: 29414769
[TBL] [Abstract][Full Text] [Related]
7. Structural analyses of a purine biosynthetic enzyme from Mycobacterium tuberculosis reveal a novel bound nucleotide.
Le Nours J; Bulloch EM; Zhang Z; Greenwood DR; Middleditch MJ; Dickson JM; Baker EN
J Biol Chem; 2011 Nov; 286(47):40706-16. PubMed ID: 21956117
[TBL] [Abstract][Full Text] [Related]
8. Characterization of two 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase isozymes from Saccharomyces cerevisiae.
Tibbetts AS; Appling DR
J Biol Chem; 2000 Jul; 275(27):20920-7. PubMed ID: 10877846
[TBL] [Abstract][Full Text] [Related]
9. Dynamic architecture of the purinosome involved in human de novo purine biosynthesis.
Kyoung M; Russell SJ; Kohnhorst CL; Esemoto NN; An S
Biochemistry; 2015 Jan; 54(3):870-80. PubMed ID: 25540829
[TBL] [Abstract][Full Text] [Related]
10. Inv(2)(p23q35) in anaplastic large-cell lymphoma induces constitutive anaplastic lymphoma kinase (ALK) tyrosine kinase activation by fusion to ATIC, an enzyme involved in purine nucleotide biosynthesis.
Ma Z; Cools J; Marynen P; Cui X; Siebert R; Gesk S; Schlegelberger B; Peeters B; De Wolf-Peeters C; Wlodarska I; Morris SW
Blood; 2000 Mar; 95(6):2144-9. PubMed ID: 10706887
[TBL] [Abstract][Full Text] [Related]
11. AICA-ribosiduria: a novel, neurologically devastating inborn error of purine biosynthesis caused by mutation of ATIC.
Marie S; Heron B; Bitoun P; Timmerman T; Van Den Berghe G; Vincent MF
Am J Hum Genet; 2004 Jun; 74(6):1276-81. PubMed ID: 15114530
[TBL] [Abstract][Full Text] [Related]
12. Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis.
Greasley SE; Horton P; Ramcharan J; Beardsley GP; Benkovic SJ; Wilson IA
Nat Struct Biol; 2001 May; 8(5):402-6. PubMed ID: 11323713
[TBL] [Abstract][Full Text] [Related]
13. Study of purinosome assembly in cell-based model systems with de novo purine synthesis and salvage pathway deficiencies.
Baresova V; Skopova V; Souckova O; Krijt M; Kmoch S; Zikanova M
PLoS One; 2018; 13(7):e0201432. PubMed ID: 30059557
[TBL] [Abstract][Full Text] [Related]
14. AICA-ribosiduria due to ATIC deficiency: Delineation of the phenotype with three novel cases, and long-term update on the first case.
Ramond F; Rio M; Héron B; Imbard A; Marie S; Billiemaz K; Denommé-Pichon AS; Kuentz P; Ceballos I; Piraud M; Vincent MF; Touraine R
J Inherit Metab Dis; 2020 Nov; 43(6):1254-1264. PubMed ID: 32557644
[TBL] [Abstract][Full Text] [Related]
15. Mapping of the bovine genes of the de novo AMP synthesis pathway.
Bønsdorff T; Gautier M; Farstad W; Rønningen K; Lingaas F; Olsaker I
Anim Genet; 2004 Dec; 35(6):438-44. PubMed ID: 15566465
[TBL] [Abstract][Full Text] [Related]
16. Identification of ATIC as a Novel Target for Chemoradiosensitization.
Liu X; Paila UD; Teraoka SN; Wright JA; Huang X; Quinlan AR; Gatti RA; Concannon P
Int J Radiat Oncol Biol Phys; 2018 Jan; 100(1):162-173. PubMed ID: 29029884
[TBL] [Abstract][Full Text] [Related]
17. Human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase. A bifunctional protein requiring dimerization for transformylase activity but not for cyclohydrolase activity.
Vergis JM; Bulock KG; Fleming KG; Beardsley GP
J Biol Chem; 2001 Mar; 276(11):7727-33. PubMed ID: 11096114
[TBL] [Abstract][Full Text] [Related]
18. A novel function for the N-terminal nucleophile hydrolase fold demonstrated by the structure of an archaeal inosine monophosphate cyclohydrolase.
Kang YN; Tran A; White RH; Ealick SE
Biochemistry; 2007 May; 46(17):5050-62. PubMed ID: 17407260
[TBL] [Abstract][Full Text] [Related]
19. ATIC inhibits autophagy in hepatocellular cancer through the AKT/FOXO3 pathway and serves as a prognostic signature for modeling patient survival.
Zhang H; Xia P; Liu J; Chen Z; Ma W; Yuan Y
Int J Biol Sci; 2021; 17(15):4442-4458. PubMed ID: 34803509
[No Abstract] [Full Text] [Related]
20. Case report of a rare purine synthesis disorder due to 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICAR) deficiency.
Joy P; Madhuri V; Palocaren T; Das S; Susan Cleave Abraham S; Korula S; Koshy B; Jose J; Chandran M; Danda S
Brain Dev; 2022 Oct; 44(9):645-649. PubMed ID: 35637059
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]