BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

218 related articles for article (PubMed ID: 32439803)

  • 21. Case report of a rare purine synthesis disorder due to 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICAR) deficiency.
    Joy P; Madhuri V; Palocaren T; Das S; Susan Cleave Abraham S; Korula S; Koshy B; Jose J; Chandran M; Danda S
    Brain Dev; 2022 Oct; 44(9):645-649. PubMed ID: 35637059
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Relationship between the catalytic sites of human bifunctional IMP synthase.
    Szabados E; Christopherson RI
    Int J Biochem Cell Biol; 1998 Aug; 30(8):933-42. PubMed ID: 9744084
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Catalytic mechanism of the cyclohydrolase activity of human aminoimidazole carboxamide ribonucleotide formyltransferase/inosine monophosphate cyclohydrolase.
    Vergis JM; Beardsley GP
    Biochemistry; 2004 Feb; 43(5):1184-92. PubMed ID: 14756554
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The last enzyme of the de novo purine synthesis pathway 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC) plays a central role in insulin signaling and the Golgi/endosomes protein network.
    Boutchueng-Djidjou M; Collard-Simard G; Fortier S; Hébert SS; Kelly I; Landry CR; Faure RL
    Mol Cell Proteomics; 2015 Apr; 14(4):1079-92. PubMed ID: 25687571
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Plasticity in the purine-thiamine metabolic network of Salmonella.
    Bazurto JV; Downs DM
    Genetics; 2011 Feb; 187(2):623-31. PubMed ID: 21135073
    [TBL] [Abstract][Full Text] [Related]  

  • 26. GPCRs regulate the assembly of a multienzyme complex for purine biosynthesis.
    Verrier F; An S; Ferrie AM; Sun H; Kyoung M; Deng H; Fang Y; Benkovic SJ
    Nat Chem Biol; 2011 Oct; 7(12):909-15. PubMed ID: 22020552
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Characterization of AICAR transformylase/IMP cyclohydrolase (ATIC) from Staphylococcus lugdunensis.
    Verma P; Kar B; Varshney R; Roy P; Sharma AK
    FEBS J; 2017 Dec; 284(24):4233-4261. PubMed ID: 29063699
    [TBL] [Abstract][Full Text] [Related]  

  • 28. CRISPR-Cas9 induced mutations along de novo purine synthesis in HeLa cells result in accumulation of individual enzyme substrates and affect purinosome formation.
    Baresova V; Krijt M; Skopova V; Souckova O; Kmoch S; Zikanova M
    Mol Genet Metab; 2016 Nov; 119(3):270-277. PubMed ID: 27590927
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Purinosome formation as a function of the cell cycle.
    Chan CY; Zhao H; Pugh RJ; Pedley AM; French J; Jones SA; Zhuang X; Jinnah H; Huang TJ; Benkovic SJ
    Proc Natl Acad Sci U S A; 2015 Feb; 112(5):1368-73. PubMed ID: 25605889
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Detecting Purinosome Metabolon Formation with Fluorescence Microscopy.
    Pedley AM; Benkovic SJ
    Methods Mol Biol; 2018; 1764():279-289. PubMed ID: 29605921
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALCL.
    Boccalatte FE; Voena C; Riganti C; Bosia A; D'Amico L; Riera L; Cheng M; Ruggeri B; Jensen ON; Goss VL; Lee K; Nardone J; Rush J; Polakiewicz RD; Comb MJ; Chiarle R; Inghirami G
    Blood; 2009 Mar; 113(12):2776-90. PubMed ID: 18845790
    [TBL] [Abstract][Full Text] [Related]  

  • 32. De novo purine nucleotide biosynthesis: cloning, sequencing and expression of a chicken PurH cDNA encoding 5-aminoimidazole-4-carboxamide-ribonucleotide transformylase-IMP cyclohydrolase.
    Ni L; Guan K; Zalkin H; Dixon JE
    Gene; 1991 Oct; 106(2):197-205. PubMed ID: 1937050
    [TBL] [Abstract][Full Text] [Related]  

  • 33. AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans.
    Wizrah MSI; Chua SMH; Luo Z; Manik MK; Pan M; Whyte JML; Robertson AAB; Kappler U; Kobe B; Fraser JA
    J Biol Chem; 2022 Oct; 298(10):102453. PubMed ID: 36063996
    [TBL] [Abstract][Full Text] [Related]  

  • 34. ATIC-Associated De Novo Purine Synthesis Is Critically Involved in Proliferative Arterial Disease.
    Ma Q; Yang Q; Xu J; Zhang X; Kim D; Liu Z; Da Q; Mao X; Zhou Y; Cai Y; Pareek V; Kim HW; Wu G; Dong Z; Song WL; Gan L; Zhang C; Hong M; Benkovic SJ; Weintraub NL; Fulton D; Asara JM; Ben-Sahra I; Huo Y
    Circulation; 2022 Nov; 146(19):1444-1460. PubMed ID: 36073366
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Analysis of substrate binding in individual active sites of bifunctional human ATIC.
    Witkowska D; Cox HL; Hall TC; Wildsmith GC; Machin DC; Webb ME
    Biochim Biophys Acta Proteins Proteom; 2018 Feb; 1866(2):254-263. PubMed ID: 29042184
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Substrate channelling by human IMP synthase.
    Szabados E; Wilson PK; Christopherson RI
    Adv Exp Med Biol; 1998; 431():241-4. PubMed ID: 9598067
    [No Abstract]   [Full Text] [Related]  

  • 37. An unusual arrangement of pur and lpx genes in the photosynthetic purple sulfur bacterium Allochromatium vinosum.
    Chen YL; Dincturk HB; Knaff DB
    Mol Biol Rep; 1999 Aug; 26(3):195-9. PubMed ID: 10532315
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Colocalization and Sequential Enzyme Activity in Aqueous Biphasic Systems: Experiments and Modeling.
    Davis BW; Aumiller WM; Hashemian N; An S; Armaou A; Keating CD
    Biophys J; 2015 Nov; 109(10):2182-94. PubMed ID: 26588576
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Role of HSP90 in the Regulation of de Novo Purine Biosynthesis.
    Pedley AM; Karras GI; Zhang X; Lindquist S; Benkovic SJ
    Biochemistry; 2018 Jun; 57(23):3217-3221. PubMed ID: 29553718
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Genetic and metabolomic analysis of AdeD and AdeI mutants of de novo purine biosynthesis: cellular models of de novo purine biosynthesis deficiency disorders.
    Duval N; Luhrs K; Wilkinson TG; Baresova V; Skopova V; Kmoch S; Vacano GN; Zikanova M; Patterson D
    Mol Genet Metab; 2013 Mar; 108(3):178-189. PubMed ID: 23394948
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.