BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 32440000)

  • 1. Dual roles of the sterol recognition region in Hedgehog protein modification.
    Purohit R; Peng DS; Vielmas E; Ondrus AE
    Commun Biol; 2020 May; 3(1):250. PubMed ID: 32440000
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hedgehog proteins create a dynamic cholesterol interface.
    Mafi A; Purohit R; Vielmas E; Lauinger AR; Lam B; Cheng YS; Zhang T; Huang Y; Kim SK; Goddard WA; Ondrus AE
    PLoS One; 2021; 16(2):e0246814. PubMed ID: 33630857
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Mechanism of Cholesterol Modification of Hedgehog Ligand.
    Banavali NK
    J Comput Chem; 2020 Mar; 41(6):520-527. PubMed ID: 31823413
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sterol A-ring plasticity in hedgehog protein cholesterolysis supports a primitive substrate selectivity mechanism.
    Ciulla DA; Wagner AG; Liu X; Cooper CL; Jorgensen MT; Wang C; Goyal P; Banavali NK; Pezzullo JL; Giner JL; Callahan BP
    Chem Commun (Camb); 2019 Feb; 55(12):1829-1832. PubMed ID: 30672911
    [TBL] [Abstract][Full Text] [Related]  

  • 5. CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids.
    Lo M; Sharir A; Paul MD; Torosyan H; Agnew C; Li A; Neben C; Marangoni P; Xu L; Raleigh DR; Jura N; Klein OD
    Nat Commun; 2022 May; 13(1):2407. PubMed ID: 35504891
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Förster resonance energy transfer-based cholesterolysis assay identifies a novel hedgehog inhibitor.
    Owen TS; Ngoje G; Lageman TJ; Bordeau BM; Belfort M; Callahan BP
    Anal Biochem; 2015 Nov; 488():1-5. PubMed ID: 26095399
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cholesterol and its derivatives in Sonic Hedgehog signaling and cancer.
    Riobo NA
    Curr Opin Pharmacol; 2012 Dec; 12(6):736-41. PubMed ID: 22832232
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Inseparable Relationship Between Cholesterol and Hedgehog Signaling.
    Siebold C; Rohatgi R
    Annu Rev Biochem; 2023 Jun; 92():273-298. PubMed ID: 37001135
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Greased hedgehogs: new links between hedgehog signaling and cholesterol metabolism.
    Breitling R
    Bioessays; 2007 Nov; 29(11):1085-94. PubMed ID: 17935218
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural basis of sterol recognition by human hedgehog receptor PTCH1.
    Qi C; Di Minin G; Vercellino I; Wutz A; Korkhov VM
    Sci Adv; 2019 Sep; 5(9):eaaw6490. PubMed ID: 31555730
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dispatching Sonic Hedgehog: Molecular Mechanisms Controlling Deployment.
    Hall ET; Cleverdon ER; Ogden SK
    Trends Cell Biol; 2019 May; 29(5):385-395. PubMed ID: 30852081
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A Single Aspartate Coordinates Two Catalytic Steps in Hedgehog Autoprocessing.
    Xie J; Owen T; Xia K; Callahan B; Wang C
    J Am Chem Soc; 2016 Aug; 138(34):10806-9. PubMed ID: 27529645
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structures of human Patched and its complex with native palmitoylated sonic hedgehog.
    Qi X; Schmiege P; Coutavas E; Wang J; Li X
    Nature; 2018 Aug; 560(7716):128-132. PubMed ID: 29995851
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Protein-Nucleic Acid Conjugation with Sterol Linkers Using Hedgehog Autoprocessing.
    Zhang X; Xu Z; Moumin DS; Ciulla DA; Owen TS; Mancusi RA; Giner JL; Wang C; Callahan BP
    Bioconjug Chem; 2019 Nov; 30(11):2799-2804. PubMed ID: 31600061
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage.
    Ali SA; Al-Jazrawe M; Ma H; Whetstone H; Poon R; Farr S; Naples M; Adeli K; Alman BA
    Arthritis Rheumatol; 2016 Jan; 68(1):127-37. PubMed ID: 26315393
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling.
    Xiao X; Tang JJ; Peng C; Wang Y; Fu L; Qiu ZP; Xiong Y; Yang LF; Cui HW; He XL; Yin L; Qi W; Wong CC; Zhao Y; Li BL; Qiu WW; Song BL
    Mol Cell; 2017 Apr; 66(1):154-162.e10. PubMed ID: 28344083
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hedgehog Cholesterolysis: Specialized Gatekeeper to Oncogenic Signaling.
    Callahan BP; Wang C
    Cancers (Basel); 2015 Oct; 7(4):2037-53. PubMed ID: 26473928
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metabolites in vertebrate Hedgehog signaling.
    Roberg-Larsen H; Strand MF; Krauss S; Wilson SR
    Biochem Biophys Res Commun; 2014 Apr; 446(3):669-74. PubMed ID: 24486313
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Posttranslational Modifications and Secretion of the Hedgehog (Hh) Proteins. Preface.
    Ho L; Riobo NA
    Methods Mol Biol; 2015; 1322():v-xi. PubMed ID: 26380847
    [No Abstract]   [Full Text] [Related]  

  • 20. A high-throughput, homogeneous, fluorescence polarization assay for inhibitors of hedgehog protein autoprocessing.
    Jiang SQ; Paulus H
    J Biomol Screen; 2010 Oct; 15(9):1082-7. PubMed ID: 20930213
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.