BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

239 related articles for article (PubMed ID: 32440158)

  • 1. Inhibition of Aurora Kinase A by Alisertib Reduces Cell Proliferation and Induces Apoptosis and Autophagy in HuH-6 Human Hepatoblastoma Cells.
    Tan J; Xu W; Lei L; Liu H; Wang H; Cao X; Xu M
    Onco Targets Ther; 2020; 13():3953-3963. PubMed ID: 32440158
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells.
    Yuan CX; Zhou ZW; Yang YX; He ZX; Zhang X; Wang D; Yang T; Wang NJ; Zhao RJ; Zhou SF
    Drug Des Devel Ther; 2015; 9():487-508. PubMed ID: 25609923
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Alisertib promotes apoptosis and autophagy in melanoma through p38 MAPK-mediated aurora a signaling.
    Shang YY; Yao M; Zhou ZW; Jian-Cui ; Li-Xia ; Hu RY; Yu YY; Qiong-Gao ; Biao-Yang ; Liu YX; Dang J; Zhou SF; Nan-Yu
    Oncotarget; 2017 Dec; 8(63):107076-107088. PubMed ID: 29291012
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Alisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cells.
    Ding YH; Zhou ZW; Ha CF; Zhang XY; Pan ST; He ZX; Edelman JL; Wang D; Yang YX; Zhang X; Duan W; Yang T; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():425-64. PubMed ID: 25624750
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells.
    Li JP; Yang YX; Liu QL; Pan ST; He ZX; Zhang X; Yang T; Chen XW; Wang D; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1627-52. PubMed ID: 25834401
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Alisertib induces G
    Liu Z; Wang F; Zhou ZW; Xia HC; Wang XY; Yang YX; He ZX; Sun T; Zhou SF
    Am J Transl Res; 2017; 9(3):845-873. PubMed ID: 28386317
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK; Wang ZL; Pan ST; Ding HQ; Au GH; He ZX; Zhou ZW; Xiao G; Yang YX; Zhang X; Yang T; Chen XW; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1555-84. PubMed ID: 25792811
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Alisertib Induces Cell Cycle Arrest, Apoptosis, Autophagy and Suppresses EMT in HT29 and Caco-2 Cells.
    Ren BJ; Zhou ZW; Zhu DJ; Ju YL; Wu JH; Ouyang MZ; Chen XW; Zhou SF
    Int J Mol Sci; 2015 Dec; 17(1):. PubMed ID: 26729093
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells.
    Wang F; Li H; Yan XG; Zhou ZW; Yi ZG; He ZX; Pan ST; Yang YX; Wang ZZ; Zhang X; Yang T; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():575-601. PubMed ID: 25632225
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of AURKA Reduces Proliferation and Survival of Gastrointestinal Cancer Cells With Activated KRAS by Preventing Activation of RPS6KB1.
    Wang-Bishop L; Chen Z; Gomaa A; Lockhart AC; Salaria S; Wang J; Lewis KB; Ecsedy J; Washington K; Beauchamp RD; El-Rifai W
    Gastroenterology; 2019 Feb; 156(3):662-675.e7. PubMed ID: 30342037
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Therapeutic Rationale to Target Highly Expressed Aurora kinase A Conferring Poor Prognosis in Cholangiocarcinoma.
    Ding X; Huang T; Peng C; Ahn KS; Andersen JB; Lewinska M; Cao Y; Xu G; Chen G; Kong B; Friess H; Shen S; Roberts LR; Wang L; Zou X
    J Cancer; 2020; 11(8):2241-2251. PubMed ID: 32127951
    [No Abstract]   [Full Text] [Related]  

  • 12. Inhibition of Aurora A Kinase by Alisertib Induces Autophagy and Cell Cycle Arrest and Increases Chemosensitivity in Human Hepatocellular Carcinoma HepG2 Cells.
    Zhu Q; Yu X; Zhou ZW; Zhou C; Chen XW; Zhou SF
    Curr Cancer Drug Targets; 2017; 17(4):386-401. PubMed ID: 27396604
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A proteomics-based investigation on the anticancer activity of alisertib, an Aurora kinase A inhibitor, in hepatocellular carcinoma Hep3B cells.
    Zhu Q; Luo M; Zhou C; Zhou Z; He Z; Yu X; Zhou S
    Am J Transl Res; 2017; 9(8):3558-3572. PubMed ID: 28861148
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Aurora kinase A inhibition and paclitaxel as targeted combination therapy for head and neck squamous cell carcinoma.
    Mazumdar A; Henderson YC; El-Naggar AK; Sen S; Clayman GL
    Head Neck; 2009 May; 31(5):625-34. PubMed ID: 19107951
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Combined inhibition of Aurora A and p21-activated kinase 1 as a new treatment strategy in breast cancer.
    Korobeynikov V; Borakove M; Feng Y; Wuest WM; Koval AB; Nikonova AS; Serebriiskii I; Chernoff J; Borges VF; Golemis EA; Shagisultanova E
    Breast Cancer Res Treat; 2019 Sep; 177(2):369-382. PubMed ID: 31254157
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MicroRNA-26-5p functions as a new inhibitor of hepatoblastoma by repressing lin-28 homolog B and aurora kinase a expression.
    Zhang Y; Zhao Y; Wu J; Liangpunsakul S; Niu J; Wang L
    Hepatol Commun; 2018 Jul; 2(7):861-871. PubMed ID: 30027143
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A SILAC-based proteomics elicits the molecular interactome of alisertib (MLN8237) in human erythroleukemia K562 cells.
    Shu LP; Zhou ZW; Zi D; He ZX; Zhou SF
    Am J Transl Res; 2015; 7(11):2442-61. PubMed ID: 26807190
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Silencing Aurora-kinase-A (AURKA) reinforced the sensitivity of diffuse large B-cell lymphoma cells to cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) via suppressing β-Catenin and RAS-extracellular signal-regulated protein kinase (ERK1/2) pathway.
    Wang S; Sun L
    Bioengineered; 2021 Dec; 12(1):8296-8308. PubMed ID: 34565287
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CDCA2 promotes melanoma progression by inhibiting ubiquitin-mediated degradation of Aurora kinase A.
    Sun W; Jin Y; Wei C; Xu Y; Liu W; Zhong J; Zou Z; Lin X; Xiang Y; Chen Y
    Eur J Cancer; 2023 Jul; 188():49-63. PubMed ID: 37196484
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The CNS-penetrating taxane drug TPI 287 potentiates antiglioma activity of the AURKA inhibitor alisertib in vivo.
    Sak M; Williams BJ; Zumbar CT; Teer L; Al-Kawaaz MNG; Kakar A; Hey AJ; Wilson MJ; Schier LM; Chen J; Lehman NL
    Cancer Chemother Pharmacol; 2023 Feb; 91(2):191-201. PubMed ID: 36694044
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.