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2. Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas. Pajtler KW; Wen J; Sill M; Lin T; Orisme W; Tang B; Hübner JM; Ramaswamy V; Jia S; Dalton JD; Haupfear K; Rogers HA; Punchihewa C; Lee R; Easton J; Wu G; Ritzmann TA; Chapman R; Chavez L; Boop FA; Klimo P; Sabin ND; Ogg R; Mack SC; Freibaum BD; Kim HJ; Witt H; Jones DTW; Vo B; Gajjar A; Pounds S; Onar-Thomas A; Roussel MF; Zhang J; Taylor JP; Merchant TE; Grundy R; Tatevossian RG; Taylor MD; Pfister SM; Korshunov A; Kool M; Ellison DW Acta Neuropathol; 2018 Aug; 136(2):211-226. PubMed ID: 29909548 [TBL] [Abstract][Full Text] [Related]
3. EZHIP/CXorf67 mimics K27M mutated oncohistones and functions as an intrinsic inhibitor of PRC2 function in aggressive posterior fossa ependymoma. Hübner JM; Müller T; Papageorgiou DN; Mauermann M; Krijgsveld J; Russell RB; Ellison DW; Pfister SM; Pajtler KW; Kool M Neuro Oncol; 2019 Jul; 21(7):878-889. PubMed ID: 30923826 [TBL] [Abstract][Full Text] [Related]
4. Into Thin Air: Hypoxia Drives Metabolic and Epigenomic Deregulation of Lethal Pediatric Ependymoma. Englinger B; Hack OA; Filbin MG Dev Cell; 2020 Jul; 54(2):134-136. PubMed ID: 32693052 [TBL] [Abstract][Full Text] [Related]
5. Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome. Panwalkar P; Clark J; Ramaswamy V; Hawes D; Yang F; Dunham C; Yip S; Hukin J; Sun Y; Schipper MJ; Chavez L; Margol A; Pekmezci M; Chung C; Banda A; Bayliss JM; Curry SJ; Santi M; Rodriguez FJ; Snuderl M; Karajannis MA; Saratsis AM; Horbinski CM; Carret AS; Wilson B; Johnston D; Lafay-Cousin L; Zelcer S; Eisenstat D; Silva M; Scheinemann K; Jabado N; McNeely PD; Kool M; Pfister SM; Taylor MD; Hawkins C; Korshunov A; Judkins AR; Venneti S Acta Neuropathol; 2017 Nov; 134(5):705-714. PubMed ID: 28733933 [TBL] [Abstract][Full Text] [Related]
6. H3 K27M mutations are extremely rare in posterior fossa group A ependymoma. Ryall S; Guzman M; Elbabaa SK; Luu B; Mack SC; Zapotocky M; Taylor MD; Hawkins C; Ramaswamy V Childs Nerv Syst; 2017 Jul; 33(7):1047-1051. PubMed ID: 28623522 [TBL] [Abstract][Full Text] [Related]
7. EZHIP: a new piece of the puzzle towards understanding pediatric posterior fossa ependymoma. Jenseit A; Camgöz A; Pfister SM; Kool M Acta Neuropathol; 2022 Jan; 143(1):1-13. PubMed ID: 34762160 [TBL] [Abstract][Full Text] [Related]
8. Evidence of H3 K27M mutations in posterior fossa ependymomas. Gessi M; Capper D; Sahm F; Huang K; von Deimling A; Tippelt S; Fleischhack G; Scherbaum D; Alfer J; Juhnke BO; von Hoff K; Rutkowski S; Warmuth-Metz M; Chavez L; Pfister SM; Pietsch T; Jones DT; Sturm D Acta Neuropathol; 2016 Oct; 132(4):635-7. PubMed ID: 27539613 [No Abstract] [Full Text] [Related]
9. EZHIP is a specific diagnostic biomarker for posterior fossa ependymomas, group PFA and diffuse midline gliomas H3-WT with EZHIP overexpression. Antin C; Tauziède-Espariat A; Debily MA; Castel D; Grill J; Pagès M; Ayrault O; Chrétien F; Gareton A; Andreiuolo F; Lechapt E; Varlet P Acta Neuropathol Commun; 2020 Nov; 8(1):183. PubMed ID: 33153494 [No Abstract] [Full Text] [Related]
10. Common molecular features of H3K27M DMGs and PFA ependymomas map to hindbrain developmental pathways. Pun M; Pratt D; Nano PR; Joshi PK; Jiang L; Englinger B; Rao A; Cieslik M; Chinnaiyan AM; Aldape K; Pfister S; Filbin MG; Bhaduri A; Venneti S Acta Neuropathol Commun; 2023 Feb; 11(1):25. PubMed ID: 36759899 [TBL] [Abstract][Full Text] [Related]
11. Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas. Bayliss J; Mukherjee P; Lu C; Jain SU; Chung C; Martinez D; Sabari B; Margol AS; Panwalkar P; Parolia A; Pekmezci M; McEachin RC; Cieslik M; Tamrazi B; Garcia BA; La Rocca G; Santi M; Lewis PW; Hawkins C; Melnick A; David Allis C; Thompson CB; Chinnaiyan AM; Judkins AR; Venneti S Sci Transl Med; 2016 Nov; 8(366):366ra161. PubMed ID: 27881822 [TBL] [Abstract][Full Text] [Related]
12. Understanding the Deadly Silence of Posterior Fossa A Ependymoma. Lin GL; Monje M Mol Cell; 2020 Jun; 78(6):999-1001. PubMed ID: 32559429 [TBL] [Abstract][Full Text] [Related]
13. Epigenomic alterations define lethal CIMP-positive ependymomas of infancy. Mack SC; Witt H; Piro RM; Gu L; Zuyderduyn S; Stütz AM; Wang X; Gallo M; Garzia L; Zayne K; Zhang X; Ramaswamy V; Jäger N; Jones DT; Sill M; Pugh TJ; Ryzhova M; Wani KM; Shih DJ; Head R; Remke M; Bailey SD; Zichner T; Faria CC; Barszczyk M; Stark S; Seker-Cin H; Hutter S; Johann P; Bender S; Hovestadt V; Tzaridis T; Dubuc AM; Northcott PA; Peacock J; Bertrand KC; Agnihotri S; Cavalli FM; Clarke I; Nethery-Brokx K; Creasy CL; Verma SK; Koster J; Wu X; Yao Y; Milde T; Sin-Chan P; Zuccaro J; Lau L; Pereira S; Castelo-Branco P; Hirst M; Marra MA; Roberts SS; Fults D; Massimi L; Cho YJ; Van Meter T; Grajkowska W; Lach B; Kulozik AE; von Deimling A; Witt O; Scherer SW; Fan X; Muraszko KM; Kool M; Pomeroy SL; Gupta N; Phillips J; Huang A; Tabori U; Hawkins C; Malkin D; Kongkham PN; Weiss WA; Jabado N; Rutka JT; Bouffet E; Korbel JO; Lupien M; Aldape KD; Bader GD; Eils R; Lichter P; Dirks PB; Pfister SM; Korshunov A; Taylor MD Nature; 2014 Feb; 506(7489):445-50. PubMed ID: 24553142 [TBL] [Abstract][Full Text] [Related]
14. Elevated CXorf67 Expression in PFA Ependymomas Suppresses DNA Repair and Sensitizes to PARP Inhibitors. Han J; Yu M; Bai Y; Yu J; Jin F; Li C; Zeng R; Peng J; Li A; Song X; Li H; Wu D; Li L Cancer Cell; 2020 Dec; 38(6):844-856.e7. PubMed ID: 33186520 [TBL] [Abstract][Full Text] [Related]
15. TERT promoter mutation and chromosome 6 loss define a high-risk subtype of ependymoma evolving from posterior fossa subependymoma. Thomas C; Thierfelder F; Träger M; Soschinski P; Müther M; Edelmann D; Förster A; Geiler C; Kim HY; Filipski K; Harter PN; Schittenhelm J; Eckert F; Ntoulias G; May SA; Stummer W; Onken J; Vajkoczy P; Schüller U; Heppner FL; Capper D; Koch A; Kaul D; Paulus W; Hasselblatt M; Schweizer L Acta Neuropathol; 2021 Jun; 141(6):959-970. PubMed ID: 33755803 [TBL] [Abstract][Full Text] [Related]
16. TULIPs decorate the three-dimensional genome of PFA ependymoma. Johnston MJ; Lee JJY; Hu B; Nikolic A; Hasheminasabgorji E; Baguette A; Paik S; Chen H; Kumar S; Chen CCL; Jessa S; Balin P; Fong V; Zwaig M; Michealraj KA; Chen X; Zhang Y; Varadharajan S; Billon P; Juretic N; Daniels C; Rao AN; Giannini C; Thompson EM; Garami M; Hauser P; Pocza T; Ra YS; Cho BK; Kim SK; Wang KC; Lee JY; Grajkowska W; Perek-Polnik M; Agnihotri S; Mack S; Ellezam B; Weil A; Rich J; Bourque G; Chan JA; Yong VW; Lupien M; Ragoussis J; Kleinman C; Majewski J; Blanchette M; Jabado N; Taylor MD; Gallo M Cell; 2024 Sep; 187(18):4926-4945.e22. PubMed ID: 38986619 [TBL] [Abstract][Full Text] [Related]
17. Molecular genetics of ependymomas and pediatric diffuse gliomas: a short review. Nobusawa S; Hirato J; Yokoo H Brain Tumor Pathol; 2014 Oct; 31(4):229-33. PubMed ID: 25182241 [TBL] [Abstract][Full Text] [Related]
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19. Chromosome 1q gain and tenascin-C expression are candidate markers to define different risk groups in pediatric posterior fossa ependymoma. Araki A; Chocholous M; Gojo J; Dorfer C; Czech T; Heinzl H; Dieckmann K; Ambros IM; Ambros PF; Slavc I; Haberler C Acta Neuropathol Commun; 2016 Aug; 4(1):88. PubMed ID: 27550150 [TBL] [Abstract][Full Text] [Related]