BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 32449219)

  • 1. Racemic total synthesis and evaluation of the biological activities of the isoquinoline-benzylisoquinoline alkaloid muraricine.
    Schütz R; Müller M; Gerndt S; Bartel K; Bracher F
    Arch Pharm (Weinheim); 2020 Jul; 353(7):e2000106. PubMed ID: 32449219
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis and biological evaluation of N-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-4-oxo-3,4-dihydrophthalazine-1-carboxamide derivatives as novel P-glycoprotein inhibitors reversing multidrug resistance.
    Qiu Q; Zhou J; Shi W; Kairuki M; Huang W; Qian H
    Bioorg Chem; 2019 May; 86():166-175. PubMed ID: 30710850
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and evaluation of Strychnos alkaloids as MDR reversal agents for cancer cell eradication.
    Munagala S; Sirasani G; Kokkonda P; Phadke M; Krynetskaia N; Lu P; Sharom FJ; Chaudhury S; Abdulhameed MD; Tawa G; Wallqvist A; Martinez R; Childers W; Abou-Gharbia M; Krynetskiy E; Andrade RB
    Bioorg Med Chem; 2014 Feb; 22(3):1148-55. PubMed ID: 24405813
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pyramidatine (Z88) Sensitizes Vincristine-Resistant Human Oral Cancer (KB/VCR) Cells to Chemotherapeutic Agents by Inhibition of P-glycoprotein.
    Liu Z; Zhu H; Qu S; Tang L; Cao L; Yu W; Yang X; Jiang S; Zhu D; Tan C; Yu L
    Anticancer Agents Med Chem; 2018; 18(2):286-294. PubMed ID: 28782465
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis and biological evaluation of novel tetrahydroisoquinoline derivatives as P-glycoprotein-mediated multidrug resistance inhibitors.
    Gao Y; Shi W; Cui J; Liu C; Bi X; Li Z; Huang W; Wang G; Qian H
    Bioorg Med Chem; 2018 May; 26(9):2420-2427. PubMed ID: 29631786
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cytotoxic isoquinoline alkaloids from the aerial parts of Corydalis incisa.
    Choi SU; Baek NI; Kim SH; Yang JH; Eun JS; Shin TY; Lim JP; Lee JH; Jeon H; Yun MY; Leem KH; Park HW; Kim DK
    Arch Pharm Res; 2007 Feb; 30(2):151-4. PubMed ID: 17366734
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Naturally occurring plant isoquinoline N-oxide alkaloids: their pharmacological and SAR activities.
    Dembitsky VM; Gloriozova TA; Poroikov VV
    Phytomedicine; 2015 Jan; 22(1):183-202. PubMed ID: 25636889
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Isolation of limonoids and alkaloids from Phellodendron amurense and their multidrug resistance (MDR) reversal activity.
    Min YD; Kwon HC; Yang MC; Lee KH; Choi SU; Lee KR
    Arch Pharm Res; 2007 Jan; 30(1):58-63. PubMed ID: 17328243
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A New Class of 1-Aryl-5,6-dihydropyrrolo[2,1-a]isoquinoline Derivatives as Reversers of P-Glycoprotein-Mediated Multidrug Resistance in Tumor Cells.
    Nevskaya AA; Matveeva MD; Borisova TN; Niso M; Colabufo NA; Boccarelli A; Purgatorio R; de Candia M; Cellamare S; Voskressensky LG; Altomare CD
    ChemMedChem; 2018 Aug; 13(15):1588-1596. PubMed ID: 29802687
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Baicalensines A and B, Two Isoquinoline Alkaloids from the Roots of
    Xue JJ; Jiang CY; Zou DL; Li BJ; Lu JC; Li DH; Lin B; Li ZL; Hua HM
    Org Lett; 2020 Oct; 22(19):7439-7442. PubMed ID: 32886519
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tetrandrine and fangchinoline, bisbenzylisoquinoline alkaloids from Stephania tetrandra can reverse multidrug resistance by inhibiting P-glycoprotein activity in multidrug resistant human cancer cells.
    Sun YF; Wink M
    Phytomedicine; 2014; 21(8-9):1110-9. PubMed ID: 24856768
    [TBL] [Abstract][Full Text] [Related]  

  • 12. P-gp Inhibition by XL019, a JAK2 Inhibitor, Increases Apoptosis of Vincristine-treated Resistant KBV20C Cells with Increased p21 and pH2AX Expression.
    Cheon JH; Kim JY; Lee BM; Kim HS; Yoon S
    Anticancer Res; 2017 Dec; 37(12):6761-6769. PubMed ID: 29187454
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hyperin Enhances the Sensitivity of HCT8/VCR Colon Cancer Cell Line to Vincristine by Down-Regulating P-Glycoprotein.
    Wang LM; Zhang MY; Zhu QS; Lu CF; Bai X
    Clin Lab; 2018 Mar; 64(3):269-275. PubMed ID: 29739100
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Topoisomerase I-mediated DNA cleavage as a guide to the development of antitumor agents derived from the marine alkaloid lamellarin D: triester derivatives incorporating amino acid residues.
    Tardy C; Facompré M; Laine W; Baldeyrou B; García-Gravalos D; Francesch A; Mateo C; Pastor A; Jiménez JA; Manzanares I; Cuevas C; Bailly C
    Bioorg Med Chem; 2004 Apr; 12(7):1697-712. PubMed ID: 15028262
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Multidrug resistance-selective antiproliferative activity of Piper amide alkaloids and synthetic analogues.
    Wang YH; Goto M; Wang LT; Hsieh KY; Morris-Natschke SL; Tang GH; Long CL; Lee KH
    Bioorg Med Chem Lett; 2014 Oct; 24(20):4818-21. PubMed ID: 25241925
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Total synthesis and biological evaluation of Amaryllidaceae alkaloids: narciclasine, ent-7-deoxypancratistatin, regioisomer of 7-deoxypancratistatin, 10b-epi-deoxypancratistatin, and truncated derivatives.
    Hudlicky T; Rinner U; Gonzalez D; Akgun H; Schilling S; Siengalewicz P; Martinot TA; Pettit GR
    J Org Chem; 2002 Dec; 67(25):8726-43. PubMed ID: 12467383
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Anticancer and Reversing Multidrug Resistance Activities of Natural Isoquinoline Alkaloids and their Structure-activity Relationship.
    Qing ZX; Huang JL; Yang XY; Liu JH; Cao HL; Xiang F; Cheng P; Zeng JG
    Curr Med Chem; 2018; 25(38):5088-5114. PubMed ID: 28933285
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antineoplastic agents. 454. Synthesis of the strong cancer cell growth inhibitors trans-dihydronarciclasine and 7-deoxy-trans-dihydronarciclasine (1a).
    Pettit GR; Ducki S; Eastham SA; Melody N
    J Nat Prod; 2009 Jul; 72(7):1279-82. PubMed ID: 19522518
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Alkaloid constituents from flower buds and leaves of sacred lotus (Nelumbo nucifera, Nymphaeaceae) with melanogenesis inhibitory activity in B16 melanoma cells.
    Nakamura S; Nakashima S; Tanabe G; Oda Y; Yokota N; Fujimoto K; Matsumoto T; Sakuma R; Ohta T; Ogawa K; Nishida S; Miki H; Matsuda H; Muraoka O; Yoshikawa M
    Bioorg Med Chem; 2013 Feb; 21(3):779-87. PubMed ID: 23270663
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Macroline-Sarpagine Bisindole Alkaloids with Antiproliferative Activity from
    Yeap JS; Saad HM; Tan CH; Sim KS; Lim SH; Low YY; Kam TS
    J Nat Prod; 2019 Nov; 82(11):3121-3132. PubMed ID: 31642315
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.