BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 32457113)

  • 1. IGF-1 receptor activity in the Golgi of migratory cancer cells depends on adhesion-dependent phosphorylation of Tyr
    Rieger L; O'Shea S; Godsmark G; Stanicka J; Kelly G; O'Connor R
    Sci Signal; 2020 May; 13(633):. PubMed ID: 32457113
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RACK1-mediated integration of adhesion and insulin-like growth factor I (IGF-I) signaling and cell migration are defective in cells expressing an IGF-I receptor mutated at tyrosines 1250 and 1251.
    Kiely PA; Leahy M; O'Gorman D; O'Connor R
    J Biol Chem; 2005 Mar; 280(9):7624-33. PubMed ID: 15611085
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The tale of a tail: The secret behind IGF-1R's oncogenic power.
    Crudden C; Girnita L
    Sci Signal; 2020 May; 13(633):. PubMed ID: 32457114
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Impaired Shc, Ras, and MAPK activation but normal Akt activation in FL5.12 cells expressing an insulin-like growth factor I receptor mutated at tyrosines 1250 and 1251.
    Leahy M; Lyons A; Krause D; O'Connor R
    J Biol Chem; 2004 Apr; 279(18):18306-13. PubMed ID: 14963047
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cooperative regulation of the invasive and metastatic phenotypes by different domains of the type I insulin-like growth factor receptor beta subunit.
    Brodt P; Fallavollita L; Khatib AM; Samani AA; Zhang D
    J Biol Chem; 2001 Sep; 276(36):33608-15. PubMed ID: 11445567
    [TBL] [Abstract][Full Text] [Related]  

  • 6. EGFR and IGF-1R in regulation of prostate cancer cell phenotype and polarity: opposing functions and modulation by T-cadherin.
    Maslova K; Kyriakakis E; Pfaff D; Frachet A; Frismantiene A; Bubendorf L; Ruiz C; Vlajnic T; Erne P; Resink TJ; Philippova M
    FASEB J; 2015 Feb; 29(2):494-507. PubMed ID: 25381040
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Insulin receptor (IR) and insulin-like growth factor receptor 1 (IGF-1R) signaling systems: novel treatment strategies for cancer.
    Singh P; Alex JM; Bast F
    Med Oncol; 2014 Jan; 31(1):805. PubMed ID: 24338270
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Controlled Signaling-Insulin-Like Growth Factor Receptor Endocytosis and Presence at Intracellular Compartments.
    Rieger L; O'Connor R
    Front Endocrinol (Lausanne); 2020; 11():620013. PubMed ID: 33584548
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Leukocyte antigen-related deficiency enhances insulin-like growth factor-1 signaling in vascular smooth muscle cells and promotes neointima formation in response to vascular injury.
    Niu XL; Li J; Hakim ZS; Rojas M; Runge MS; Madamanchi NR
    J Biol Chem; 2007 Jul; 282(27):19808-19. PubMed ID: 17500057
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FES-related tyrosine kinase activates the insulin-like growth factor-1 receptor at sites of cell adhesion.
    Stanicka J; Rieger L; O'Shea S; Cox O; Coleman M; O'Flanagan C; Addario B; McCabe N; Kennedy R; O'Connor R
    Oncogene; 2018 Jun; 37(23):3131-3150. PubMed ID: 29540831
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Insulin-like growth factor-1 (IGF-1) receptor-insulin receptor substrate complexes in the uterus. Altered signaling response to estradiol in the IGF-1(m/m) mouse.
    Richards RG; Walker MP; Sebastian J; DiAugustine RP
    J Biol Chem; 1998 May; 273(19):11962-9. PubMed ID: 9565625
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Serine phosphorylation of the insulin-like growth factor I (IGF-1) receptor C-terminal tail restrains kinase activity and cell growth.
    Kelly GM; Buckley DA; Kiely PA; Adams DR; O'Connor R
    J Biol Chem; 2012 Aug; 287(33):28180-94. PubMed ID: 22685298
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Complement component 1, q subcomponent binding protein (C1QBP) in lipid rafts mediates hepatic metastasis of pancreatic cancer by regulating IGF-1/IGF-1R signaling.
    Shi H; Fang W; Liu M; Fu D
    Int J Cancer; 2017 Oct; 141(7):1389-1401. PubMed ID: 28608366
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phosphatidylinositol 3-kinase (PI3K) activity bound to insulin-like growth factor-I (IGF-I) receptor, which is continuously sustained by IGF-I stimulation, is required for IGF-I-induced cell proliferation.
    Fukushima T; Nakamura Y; Yamanaka D; Shibano T; Chida K; Minami S; Asano T; Hakuno F; Takahashi S
    J Biol Chem; 2012 Aug; 287(35):29713-21. PubMed ID: 22767591
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Over-accumulation of nuclear IGF-1 receptor in tumor cells requires elevated expression of the receptor and the SUMO-conjugating enzyme Ubc9.
    Deng H; Lin Y; Badin M; Vasilcanu D; Strömberg T; Jernberg-Wiklund H; Sehat B; Larsson O
    Biochem Biophys Res Commun; 2011 Jan; 404(2):667-71. PubMed ID: 21147068
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The role of Shc and insulin-like growth factor 1 receptor in mediating the translocation of estrogen receptor alpha to the plasma membrane.
    Song RX; Barnes CJ; Zhang Z; Bao Y; Kumar R; Santen RJ
    Proc Natl Acad Sci U S A; 2004 Feb; 101(7):2076-81. PubMed ID: 14764897
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RACK1, an insulin-like growth factor I (IGF-I) receptor-interacting protein, modulates IGF-I-dependent integrin signaling and promotes cell spreading and contact with extracellular matrix.
    Hermanto U; Zong CS; Li W; Wang LH
    Mol Cell Biol; 2002 Apr; 22(7):2345-65. PubMed ID: 11884618
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The differential effects of pp120 (Ceacam 1) on the mitogenic action of insulin and insulin-like growth factor 1 are regulated by the nonconserved tyrosine 1316 in the insulin receptor.
    Soni P; Lakkis M; Poy MN; Fernström MA; Najjar SM
    Mol Cell Biol; 2000 Jun; 20(11):3896-905. PubMed ID: 10805733
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Compensatory insulin receptor (IR) activation on inhibition of insulin-like growth factor-1 receptor (IGF-1R): rationale for cotargeting IGF-1R and IR in cancer.
    Buck E; Gokhale PC; Koujak S; Brown E; Eyzaguirre A; Tao N; Rosenfeld-Franklin M; Lerner L; Chiu MI; Wild R; Epstein D; Pachter JA; Miglarese MR
    Mol Cancer Ther; 2010 Oct; 9(10):2652-64. PubMed ID: 20924128
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nuclear translocation of IGF-1R via p150(Glued) and an importin-β/RanBP2-dependent pathway in cancer cells.
    Packham S; Warsito D; Lin Y; Sadi S; Karlsson R; Sehat B; Larsson O
    Oncogene; 2015 Apr; 34(17):2227-38. PubMed ID: 24909165
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.