226 related articles for article (PubMed ID: 32476252)
21. IFNɣ but not IFNα increases recognition of insulin defective ribosomal product-derived antigen to amplify islet autoimmunity.
Thomaidou S; Munoz Garcia A; de Lange S; Gan J; van der Slik AR; Hoeben RC; Roep BO; Carlotti F; Zaldumbide A
Diabetologia; 2023 Nov; 66(11):2075-2086. PubMed ID: 37581620
[TBL] [Abstract][Full Text] [Related]
22. A novel highly selective allosteric inhibitor of tyrosine kinase 2 (TYK2) can block inflammation- and autoimmune-related pathways.
Chen CX; Zhang W; Qu S; Xia F; Zhu Y; Chen B
Cell Commun Signal; 2023 Oct; 21(1):287. PubMed ID: 37845748
[TBL] [Abstract][Full Text] [Related]
23. CDK11 Promotes Cytokine-Induced Apoptosis in Pancreatic Beta Cells Independently of Glucose Concentration and Is Regulated by Inflammation in the NOD Mouse Model.
Sala E; Vived C; Luna J; Saavedra-Ávila NA; Sengupta U; Castaño AR; Villar-Pazos S; Haba L; Verdaguer J; Ropero AB; Stratmann T; Pizarro J; Vázquez-Carrera M; Nadal A; Lahti JM; Mora C
Front Immunol; 2021; 12():634797. PubMed ID: 33664748
[TBL] [Abstract][Full Text] [Related]
24. The miRNAs miR-211-5p and miR-204-5p modulate ER stress in human beta cells.
Grieco FA; Schiavo AA; Brozzi F; Juan-Mateu J; Bugliani M; Marchetti P; Eizirik DL
J Mol Endocrinol; 2019 Aug; 63(2):139-149. PubMed ID: 31277072
[TBL] [Abstract][Full Text] [Related]
25. PTPN2 Regulates the Interferon Signaling and Endoplasmic Reticulum Stress Response in Pancreatic β-Cells in Autoimmune Diabetes.
Elvira B; Vandenbempt V; Bauzá-Martinez J; Crutzen R; Negueruela J; Ibrahim H; Winder ML; Brahma MK; Vekeriotaite B; Martens PJ; Singh SP; Rossello F; Lybaert P; Otonkoski T; Gysemans C; Wu W; Gurzov EN
Diabetes; 2022 Apr; 71(4):653-668. PubMed ID: 35044456
[TBL] [Abstract][Full Text] [Related]
26. BCL-XL Overexpression Protects Pancreatic β-Cells against Cytokine- and Palmitate-Induced Apoptosis.
Perez-Serna AA; Dos Santos RS; Ripoll C; Nadal A; Eizirik DL; Marroqui L
Int J Mol Sci; 2023 Mar; 24(6):. PubMed ID: 36982731
[TBL] [Abstract][Full Text] [Related]
27. Stearoyl CoA desaturase is a gatekeeper that protects human beta cells against lipotoxicity and maintains their identity.
Oshima M; Pechberty S; Bellini L; Göpel SO; Campana M; Rouch C; Dairou J; Cosentino C; Fantuzzi F; Toivonen S; Marchetti P; Magnan C; Cnop M; Le Stunff H; Scharfmann R
Diabetologia; 2020 Feb; 63(2):395-409. PubMed ID: 31796987
[TBL] [Abstract][Full Text] [Related]
28. The rs2304256 Polymorphism in TYK2 Gene Is Associated with Protection for Type 1 Diabetes Mellitus.
Pellenz FM; Dieter C; Duarte GCK; Canani LH; de Souza BM; Crispim D
Diabetes Metab J; 2021 Nov; 45(6):899-908. PubMed ID: 34225445
[TBL] [Abstract][Full Text] [Related]
29. ADAR1-dependent editing regulates human β cell transcriptome diversity during inflammation.
Szymczak F; Cohen-Fultheim R; Thomaidou S; de Brachène AC; Castela A; Colli M; Marchetti P; Levanon E; Eizirik D; Zaldumbide A
Front Endocrinol (Lausanne); 2022; 13():1058345. PubMed ID: 36518246
[TBL] [Abstract][Full Text] [Related]
30. Potent and Selective Knockdown of Tyrosine Kinase 2 by Antisense Oligonucleotides.
Tran NV; Nguyen LTA; Lim KW; Phan AT
Immunohorizons; 2021 Feb; 5(2):70-80. PubMed ID: 33542028
[TBL] [Abstract][Full Text] [Related]
31. Marburg virus evades interferon responses by a mechanism distinct from ebola virus.
Valmas C; Grosch MN; Schümann M; Olejnik J; Martinez O; Best SM; Krähling V; Basler CF; Mühlberger E
PLoS Pathog; 2010 Jan; 6(1):e1000721. PubMed ID: 20084112
[TBL] [Abstract][Full Text] [Related]
32. Endogenous mitochondrial double-stranded RNA is not an activator of the type I interferon response in human pancreatic beta cells.
Coomans de Brachène A; Castela A; Musuaya AE; Marselli L; Marchetti P; Eizirik DL
Auto Immun Highlights; 2021 Mar; 12(1):6. PubMed ID: 33773604
[TBL] [Abstract][Full Text] [Related]
33. Tyrosine kinase 2 modulates splenic B cells through type I IFN and TLR7 signaling.
Bodega-Mayor I; Delgado-Wicke P; Arrabal A; Alegría-Carrasco E; Nicolao-Gómez A; Jaén-Castaño M; Espadas C; Dopazo A; Martín-Gayo E; Gaspar ML; de Andrés B; Fernández-Ruiz E
Cell Mol Life Sci; 2024 Apr; 81(1):199. PubMed ID: 38683377
[TBL] [Abstract][Full Text] [Related]
34. Subtyping of Type 1 Diabetes as Classified by Anti-GAD Antibody, IgE Levels, and Tyrosine kinase 2 (TYK2) Promoter Variant in the Japanese.
Mine K; Hirakawa K; Kondo S; Minami M; Okada A; Tsutsu N; Yokogawa Y; Hibio Y; Kojima F; Fujimoto S; Kurisaki H; Anzai K; Yoshikai Y; Nagafuchi S;
EBioMedicine; 2017 Sep; 23():46-51. PubMed ID: 28826655
[TBL] [Abstract][Full Text] [Related]
35. MANF protects human pancreatic beta cells against stress-induced cell death.
Hakonen E; Chandra V; Fogarty CL; Yu NY; Ustinov J; Katayama S; Galli E; Danilova T; Lindholm P; Vartiainen A; Einarsdottir E; Krjutškov K; Kere J; Saarma M; Lindahl M; Otonkoski T
Diabetologia; 2018 Oct; 61(10):2202-2214. PubMed ID: 30032427
[TBL] [Abstract][Full Text] [Related]
36. DNA damage to β cells in culture recapitulates features of senescent β cells that accumulate in type 1 diabetes.
Brawerman G; Pipella J; Thompson PJ
Mol Metab; 2022 Aug; 62():101524. PubMed ID: 35660116
[TBL] [Abstract][Full Text] [Related]
37. C/EBP homologous protein contributes to cytokine-induced pro-inflammatory responses and apoptosis in β-cells.
Allagnat F; Fukaya M; Nogueira TC; Delaroche D; Welsh N; Marselli L; Marchetti P; Haefliger JA; Eizirik DL; Cardozo AK
Cell Death Differ; 2012 Nov; 19(11):1836-46. PubMed ID: 22653339
[TBL] [Abstract][Full Text] [Related]
38. Inhibition of TYK2 and JAK1 ameliorates imiquimod-induced psoriasis-like dermatitis by inhibiting IL-22 and the IL-23/IL-17 axis.
Works MG; Yin F; Yin CC; Yiu Y; Shew K; Tran TT; Dunlap N; Lam J; Mitchell T; Reader J; Stein PL; D'Andrea A
J Immunol; 2014 Oct; 193(7):3278-87. PubMed ID: 25156366
[TBL] [Abstract][Full Text] [Related]
39. The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines.
Eizirik DL; Sammeth M; Bouckenooghe T; Bottu G; Sisino G; Igoillo-Esteve M; Ortis F; Santin I; Colli ML; Barthson J; Bouwens L; Hughes L; Gregory L; Lunter G; Marselli L; Marchetti P; McCarthy MI; Cnop M
PLoS Genet; 2012; 8(3):e1002552. PubMed ID: 22412385
[TBL] [Abstract][Full Text] [Related]
40. Selective Tyk2 inhibitors as potential therapeutic agents: a patent review (2015-2018).
He X; Chen X; Zhang H; Xie T; Ye XY
Expert Opin Ther Pat; 2019 Feb; 29(2):137-149. PubMed ID: 30621465
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
